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One or more keywords matched the following items that are connected to Cohen, Ezra
Item TypeName
Concept Protein-Tyrosine Kinases
Concept Protein Kinases
Concept Mitogen-Activated Protein Kinases
Concept Receptor Protein-Tyrosine Kinases
Concept Mitogen-Activated Protein Kinase 3
Concept Cyclin-Dependent Kinase Inhibitor p16
Concept Protein Kinase C
Concept Class I Phosphatidylinositol 3-Kinases
Concept TOR Serine-Threonine Kinases
Concept Phosphatidylinositol 3-Kinases
Concept MAP Kinase Signaling System
Concept Ribosomal Protein S6 Kinases, 70-kDa
Concept Protein Kinase C-alpha
Concept Class Ib Phosphatidylinositol 3-Kinase
Concept Protein Kinase Inhibitors
Concept p38 Mitogen-Activated Protein Kinases
Academic Article Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck.
Academic Article A phase II trial of perifosine, an oral alkylphospholipid, in recurrent or metastatic head and neck cancer.
Academic Article Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase.
Academic Article The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma.
Academic Article A feed-forward loop involving protein kinase Calpha and microRNAs regulates tumor cell cycle.
Academic Article Response of some head and neck cancers to epidermal growth factor receptor tyrosine kinase inhibitors may be linked to mutation of ERBB2 rather than EGFR.
Academic Article A phase I study of sirolimus and bevacizumab in patients with advanced malignancies.
Academic Article Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer.
Academic Article Efficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context.
Academic Article Factors associated with clinical benefit from epidermal growth factor receptor inhibitors in recurrent and metastatic squamous cell carcinoma of the head and neck.
Academic Article Effect of complementary pathway blockade on efficacy of combination enzastaurin and rapamycin.
Academic Article Phase I studies of sirolimus alone or in combination with pharmacokinetic modulators in advanced cancer patients.
Academic Article Sorafenib inhibits MAPK-mediated proliferation in a Barrett's esophageal adenocarcinoma cell line.
Academic Article Cabozantinib for the treatment of advanced medullary thyroid cancer.
Academic Article mTOR: the mammalian target of replication.
Academic Article Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients.
Academic Article Mechanisms of resistance to EGFR inhibitors in head and neck cancer.
Academic Article New approaches to thyroid cancer.
Academic Article Novel molecular targeted therapies for refractory thyroid cancer.
Academic Article Forthcoming receptor tyrosine kinase inhibitors.
Academic Article Treatment of squamous cell carcinoma of the head and neck in the metastatic and refractory settings: advances in chemotherapy and the emergence of small molecule epidermal growth factor receptor kinase inhibitors.
Academic Article Molecular phenotype predicts sensitivity of squamous cell carcinoma of the head and neck to epidermal growth factor receptor inhibition.
Academic Article Epidermal growth factor receptor directed therapy in head and neck cancer.
Academic Article Role of epidermal growth factor receptor pathway-targeted therapy in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck.
Academic Article DNA repair biomarkers XPF and phospho-MAPKAP kinase 2 correlate with clinical outcome in advanced head and neck cancer.
Academic Article Pharmacokinetics of single-agent axitinib across multiple solid tumor types.
Academic Article Diarrhea associated with afatinib: an oral ErbB family blocker.
Academic Article Targeting the PI3K/AKT/mTOR pathway in squamous cell carcinoma of the head and neck.
Academic Article A Phase II trial of axitinib in patients with various histologic subtypes of advanced thyroid cancer: long-term outcomes and pharmacokinetic/pharmacodynamic analyses.
Academic Article Genetic profiling of advanced radioactive iodine-resistant differentiated thyroid cancer and correlation with axitinib efficacy.
Academic Article Afatinib versus placebo as adjuvant therapy after chemoradiation in a double-blind, phase III study (LUX-Head & Neck 2) in patients with primary unresected, clinically intermediate-to-high-risk head and neck cancer: study protocol for a randomized controlled trial.
Academic Article Cabozantinib in progressive medullary thyroid cancer.
Academic Article An open-label single-arm, phase II trial of zalutumumab, a human monoclonal anti-EGFR antibody, in patients with platinum-refractory squamous cell carcinoma of the head and neck.
Academic Article A phase Ib trial of LY2584702 tosylate, a p70 S6 inhibitor, in combination with erlotinib or everolimus in patients with solid tumours.
Academic Article p62/SQSTM1 accumulation in squamous cell carcinoma of head and neck predicts sensitivity to phosphatidylinositol 3-kinase pathway inhibitors.
Academic Article Lenvatinib in Advanced, Radioactive Iodine-Refractory, Differentiated Thyroid Carcinoma.
Academic Article Phase II trial of dasatinib for recurrent or metastatic c-KIT expressing adenoid cystic carcinoma and for nonadenoid cystic malignant salivary tumors.
Academic Article Erlotinib and the Risk of Oral Cancer: The Erlotinib Prevention of Oral Cancer (EPOC) Randomized Clinical Trial.
Academic Article Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition.
Academic Article PI3K? is a molecular switch that controls immune suppression.
Academic Article Monitoring Daily Dynamics of Early Tumor Response to Targeted Therapy by Detecting Circulating Tumor DNA in Urine.
Academic Article A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancers.
Academic Article A pharmacodynamic study of sirolimus and metformin in patients with advanced solid tumors.
Academic Article Prognostic Role of p16 in Nonoropharyngeal Head and Neck Cancer.
Academic Article Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer.
Academic Article Hereditary oral squamous cell carcinoma associated with CDKN2A germline mutation: a case report.
Grant Maximizing Efficacy of EGFR Inhibitors by Defining Resistance Mechanisms
Grant Rapamycin as an Antineoplastic Agent
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