Loading...
The University of Chicago Header Logo
Keywords
Last Name
Institution

Connection

Search Results to Jean Greenberg

This is a "connection" page, showing the details of why an item matched the keywords from your search.

                     
                     

One or more keywords matched the following properties of Greenberg, Jean

PropertyValue
overview Research My broad interest is in how organisms adapt to a changing environment. My lab studies this in the context of pathogen-host interactions using the gram negative pathogen Pseudomonas syringae and its interaction with several plants: the non-crop models Arabidopsis thaliana and Nicotiana benthamiana, and the crop plants tomato and snap beans. In response to infection, plants mount a complex local defense response involving cell suicide, changes at the plasma membrane, the crosslinking of cell wall components, production of antimicrobials and defense gene activation. Some leaf infections induce a primed state that allows plants to respond faster when a second infection occurs on distal leaves (systemic acquired resistance, SAR). Interactions of roots with beneficial microbes also induces a primed state in the aerial part of the plant (and induced systemic resistance, ISR). Although SAR and ISR were considered different immune programs, we have found that some of the same are proteins required for both systemic programs. These proteins are involved in mobilizing small molecule signals. The lab investigates plant defense and pathogen virulence mechanisms. We study how plants regulate their responses to pathogens by (1) using plant mutants that express one or more aspects of the defense response in the absence of pathogens or are compromised for local defense activation or SAR, (2) discovering and tracking the production and movement of novel defense signals and pathogen-derived molecules, and (3) exploiting secreted virulence effector proteins from the pathogen to discover immune components and discern how they are modified. This involves combining genetic analysis (including mosaic plants in which only some cells/tissues express specific defense components) with biochemistry and cell biology. We are very interested in how the defense response is coordinated and towards this end, we are investigating the sites of action at the tissue and subcellular levels of key SAR/ISR proteins. On the pathogen side, we are also characterizing how P. syringae uses its type III secretion apparatus and secreted effectors to modulate immunity and colonize plant tissue, including the surfaces of a leaf, a unique niche. We are using proteomic approaches to discern how pathogen effectors post-translationally modify both other pathogen effectors and host immune complexes to suppress signaling. We are interested in exploiting what we learn about P. syringae effectors to study orthologous effectors from diverse pathogens of both plants and animals. A recent additional interest is in peptide trafficking and signal output as it relates to development and microbial interactions. Our lab welcomes participants from all over the world and at many levels of education (high school, college, predoctoral, postdoctoral and teachers). Professional Activities and Service I have been a Senior Editor of The Plant Cell, a Reviewing Editor of eLIFE and Secretary to the Board of Directors of the International Society of Plant-Microbe Interactions. I am a member of the American Society of Plant Biology and the Society for Experimental Biology. I participated in developing and writing a recently published white paper concerning the promotion of plant heath: "Foundational and translational research opportunities to improve plant health." Currently I am a member of the Plant Biology Advisory Board for Landmarks. I am a strong advocate for diversity in science and serve on the University of Chicago Division of Biology's Diversity Committee and on the steering committee of the Molecular Genetics and Cell Biology Department's National Science Foundation-sponsored Research Education for Undergraduates program.

One or more keywords matched the following items that are connected to Greenberg, Jean

Item TypeName
Concept Bacterial Outer Membrane Proteins
Concept Bacterial Proteins
Concept DNA-Binding Proteins
Concept Heat-Shock Proteins
Concept Plant Proteins
Concept Repressor Proteins
Concept HSP70 Heat-Shock Proteins
Concept Apoptosis Regulatory Proteins
Concept Green Fluorescent Proteins
Concept Arabidopsis Proteins
Concept Recombinant Proteins
Concept Escherichia coli Proteins
Concept Intracellular Signaling Peptides and Proteins
Concept Carrier Proteins
Concept Recombinant Fusion Proteins
Academic Article Programmed cell death: a way of life for plants.
Academic Article The gain-of-function Arabidopsis acd6 mutant reveals novel regulation and function of the salicylic acid signaling pathway in controlling cell death, defenses, and cell growth.
Academic Article The Arabidopsis aberrant growth and death2 mutant shows resistance to Pseudomonas syringae and reveals a role for NPR1 in suppressing hypersensitive cell death.
Academic Article A role for salicylic acid and NPR1 in regulating cell growth in Arabidopsis.
Academic Article The Arabidopsis-accelerated cell death gene ACD2 encodes red chlorophyll catabolite reductase and suppresses the spread of disease symptoms.
Academic Article Functional analysis of the type III effectors AvrRpt2 and AvrRpm1 of Pseudomonas syringae with the use of a single-copy genomic integration system.
Academic Article Identifying type III effectors of plant pathogens and analyzing their interaction with plant cells.
Academic Article A functional screen for the type III (Hrp) secretome of the plant pathogen Pseudomonas syringae.
Academic Article ACD6, a novel ankyrin protein, is a regulator and an effector of salicylic acid signaling in the Arabidopsis defense response.
Academic Article Divergent roles in Arabidopsis thaliana development and defense of two homologous genes, aberrant growth and death2 and AGD2-LIKE DEFENSE RESPONSE PROTEIN1, encoding novel aminotransferases.
Academic Article A key role for ALD1 in activation of local and systemic defenses in Arabidopsis.
Academic Article The mitochondrion--an organelle commonly involved in programmed cell death in Arabidopsis thaliana.
Academic Article Bioinformatics correctly identifies many type III secretion substrates in the plant pathogen Pseudomonas syringae and the biocontrol isolate P. fluorescens SBW25.
Academic Article Structure-function analysis of the plasma membrane- localized Arabidopsis defense component ACD6.
Academic Article Signaling pathways that regulate the enhanced disease resistance of Arabidopsis "defense, no death" mutants.
Academic Article Proposed guidelines for a unified nomenclature and phylogenetic analysis of type III Hop effector proteins in the plant pathogen Pseudomonas syringae.
Academic Article The type III effector repertoire of Pseudomonas syringae pv. syringae B728a and its role in survival and disease on host and non-host plants.
Academic Article Pseudomonas syringae hijacks plant stress chaperone machinery for virulence.
Academic Article A key role for the Arabidopsis WIN3 protein in disease resistance triggered by Pseudomonas syringae that secrete AvrRpt2.
Academic Article Type III secretion and effectors shape the survival and growth pattern of Pseudomonas syringae on leaf surfaces.
Academic Article SGT1b is required for HopZ3-mediated suppression of the epiphytic growth of Pseudomonas syringae on N. benthamiana.
Academic Article Arabidopsis proteins important for modulating defense responses to Pseudomonas syringae that secrete HopW1-1.
Academic Article Genetic analysis of acd6-1 reveals complex defense networks and leads to identification of novel defense genes in Arabidopsis.
Academic Article Accelerated cell death 2 suppresses mitochondrial oxidative bursts and modulates cell death in Arabidopsis.
Academic Article Programmed cell death in plants: a pathogen-triggered response activated coordinately with multiple defense functions.
Academic Article Arabidopsis ACCELERATED CELL DEATH2 modulates programmed cell death.
Academic Article A J domain virulence effector of Pseudomonas syringae remodels host chloroplasts and suppresses defenses.
Academic Article Priming in systemic plant immunity.
Academic Article Comparative large-scale analysis of interactions between several crop species and the effector repertoires from multiple pathovars of Pseudomonas and Ralstonia.
Academic Article A conserved cysteine motif is critical for rice ceramide kinase activity and function.
Academic Article Positive control of a global antioxidant defense regulon activated by superoxide-generating agents in Escherichia coli.
Academic Article Loss of ceramide kinase in Arabidopsis impairs defenses and promotes ceramide accumulation and mitochondrial H2O2 bursts.
Academic Article Salicylic acid regulates Arabidopsis microbial pattern receptor kinase levels and signaling.
Academic Article Plant pathogenic bacteria target the actin microfilament network involved in the trafficking of disease defense components.
Academic Article ALD1 Regulates Basal Immune Components and Early Inducible Defense Responses in Arabidopsis.
Academic Article HopW1 from Pseudomonas syringae disrupts the actin cytoskeleton to promote virulence in Arabidopsis.
Academic Article Salicylic acid signaling controls the maturation and localization of the arabidopsis defense protein ACCELERATED CELL DEATH6.
Academic Article Arabidopsis AZI1 family proteins mediate signal mobilization for systemic defence priming.
Academic Article Linking pattern recognition and salicylic acid responses in Arabidopsis through ACCELERATED CELL DEATH6 and receptors.
Academic Article Acetylation of an NB-LRR Plant Immune-Effector Complex Suppresses Immunity.
Academic Article A Suite of Receptor-Like Kinases and a Putative Mechano-Sensitive Channel Are Involved in Autoimmunity and Plasma Membrane-Based Defenses in Arabidopsis.
Academic Article Flagellin peptide flg22 gains access to long-distance trafficking in Arabidopsis via its receptor, FLS2.
Grant Post-translational Modifications as Modulators of Crop Plant Defense Signaling: a Systems Approach
Grant Defense amplification and priming in Arabidopsis
Academic Article Posttranscriptional repression of Escherichia coli OmpF protein in response to redox stress: positive control of the micF antisense RNA by the soxRS locus.
Academic Article A global response induced in Escherichia coli by redox-cycling agents overlaps with that induced by peroxide stress.
Academic Article Overproduction of peroxide-scavenging enzymes in Escherichia coli suppresses spontaneous mutagenesis and sensitivity to redox-cycling agents in oxyR-mutants.
Academic Article Simple strategies to enhance discovery of acetylation post-translational modifications by quadrupole-orbitrap LC-MS/MS.
Academic Article PROHIBITIN3 Forms Complexes with ISOCHORISMATE SYNTHASE1 to Regulate Stress-Induced Salicylic Acid Biosynthesis in Arabidopsis.
Academic Article Kinases and protein motifs required for AZI1 plastid localization and trafficking during plant defense induction.
Academic Article ALD1 accumulation in Arabidopsis epidermal plastids confers local and non-autonomous disease resistance.
Academic Article Pseudomonas syringae effector HopZ3 suppresses the bacterial AvrPto1-tomato PTO immune complex via acetylation.

Search Criteria
  • Antimicrobial
  • proteins