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One or more keywords matched the following properties of Chiu, Brian Chih-Hung
keywords Multiple Myeloma
overview Dr. Chiu investigates the causes and outcomes of lymphoma and multiple myeloma in racial/ethnic and geographically diverse populations using integrated modern molecular techniques and epidemiologic approaches. His current main focus areas are: (1) developing novel epigenetics-based biomarkers in circulating cell-free DNA for prognostication and management of cancers, especially multiple myeloma, (2) identifying lifestyle, biological, and treatment factors that influence the survival and outcomes of multiple myeloma patients, and (3) studying lifestyles, environmental exposures, genetics, and epigenetics that are associated with risks of developing non-Hodgkin lymphoma and multiple myeloma. He is also an active researcher in large international consortia, including the International Lymphoma Epidemiology Consortium (InterLymph), International Multiple Myeloma Consortium (now InterLymph-Myeloma Working Group), and the NCI AsiaLymph. Dr. Chiu’s ongoing NIH-funded and other major research projects include: • Epidemiology of Multiple Myeloma Outcomes at UChicago (EMMOC): Dr. Chiu and his colleagues are enrolling patients with multiple myeloma at the UChicago Medical Center to characterize serial epigenetic signatures in circulating cell-free DNA and evaluate integration with quantitative image-based markers for minimally-invasive assessment of response to myeloma treatment. • Study at UChicago for Cancer Epigenetic EpiDemiology (SUCCEED): Dr. Chiu and his team use a sensitive single-base epigenetic profiling technology to characterize epigenetic modifications in cancers for liquid biopsy-based biomarker discovery in cancer detection and monitoring. • UChicago Myeloma Epidemiology Study: In this clinic-based cohort study at the University of Chicago, Dr. Chiu and his team investigate lifestyle, diet, cytogenetics, genetics, and epigenetic modifications, particularly 5-hydroxymethylcytosine, implicated in the racial/ethnic disparities in the development and outcomes of multiple myeloma. • International Lymphoma Epidemiology Consortium (InterLymph) and AsiaLymph: Dr. Chiu is collaborating with a large group of multi-institute international investigators to investigate the role of environmental exposures and genetic factors in the development of lymphoid malignancies. One of the ongoing major multi-institute initiatives is the InterLymph Genome-Wide Association Study of Lymphoid Malignancies and Related Disorders. Dr. Chiu was also the principal investigator of Taiwan Center for the NCI AsiaLymph study to investigate the contribution of environmental, occupational, and genetic factors to lymphoma risk in Eastern Asia.
One or more keywords matched the following items that are connected to Chiu, Brian Chih-Hung
Item TypeName
Academic Article Body mass index, abnormal glucose metabolism, and mortality from hematopoietic cancer.
Academic Article A pooled analysis of cigarette smoking and risk of multiple myeloma from the international multiple myeloma consortium.
Academic Article A pooled analysis of alcohol consumption and risk of multiple myeloma in the international multiple myeloma consortium.
Academic Article Multiple myeloma and occupation: a pooled analysis by the International Multiple Myeloma Consortium.
Academic Article Multiple myeloma and family history of lymphohaematopoietic cancers: Results from the International Multiple Myeloma Consortium.
Academic Article A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci.
Academic Article Young Adult and Usual Adult Body Mass Index and Multiple Myeloma Risk: A Pooled Analysis in the International Multiple Myeloma Consortium (IMMC).
Academic Article Pooled study of occupational exposure to aromatic hydrocarbon solvents and risk of multiple myeloma.
Academic Article Depressive symptoms, mental health-related quality of life, and survival among older patients with multiple myeloma.
Academic Article A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry.
Academic Article Targets of biologic disease-modifying antirheumatic drugs and risk of multiple myeloma.
Academic Article Self-reported health and survival in older patients diagnosed with multiple myeloma.
Academic Article Variability in Cytogenetic Testing for Multiple Myeloma: A Comprehensive Analysis From Across the United States.
Academic Article Racial differences in treatment and outcomes in multiple myeloma: a multiple myeloma research foundation analysis.
Academic Article Sex differences in outcomes in multiple myeloma.
Academic Article Racial Disparities in Intravenous Bisphosphonate Use Among Older Patients With Multiple Myeloma Enrolled in Medicare.
Academic Article Evaluation of Frequency of Administration of Intravenous Bisphosphonate and Recurrent Skeletal-Related Events in Patients With Multiple Myeloma.
Academic Article Genome-wide profiling of 5-hydroxymethylcytosines in circulating cell-free DNA reveals population-specific pathways in the development of multiple myeloma.
Academic Article Body Mass Index and Overall Survival of Patients with Newly Diagnosed Multiple Myeloma.
Academic Article Geospatial analysis of population-based incidence of multiple myeloma in the United States.
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  • Multiple Myeloma