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One or more keywords matched the following properties of Chiu, Brian Chih-Hung
PropertyValue
keywords Translational population research
overview Dr. Chiu investigates the causes and outcomes of lymphoma and multiple myeloma in racial/ethnic and geographically diverse populations using integrated modern molecular techniques and epidemiologic approaches. His current main focus areas are: (1) developing novel epigenetics-based biomarkers in circulating cell-free DNA for prognostication and management of cancers, especially multiple myeloma, (2) identifying lifestyle, biological, and treatment factors that influence the survival and outcomes of multiple myeloma patients, and (3) studying lifestyles, environmental exposures, genetics, and epigenetics that are associated with risks of developing non-Hodgkin lymphoma and multiple myeloma. He is also an active researcher in large international consortia, including the International Lymphoma Epidemiology Consortium (InterLymph), International Multiple Myeloma Consortium (now InterLymph-Myeloma Working Group), and the NCI AsiaLymph. Dr. Chiu’s ongoing NIH-funded and other major research projects include: • Epidemiology of Multiple Myeloma Outcomes at UChicago (EMMOC): Dr. Chiu and his colleagues are enrolling patients with multiple myeloma at the UChicago Medical Center to characterize serial epigenetic signatures in circulating cell-free DNA and evaluate integration with quantitative image-based markers for minimally-invasive assessment of response to myeloma treatment. • Study at UChicago for Cancer Epigenetic EpiDemiology (SUCCEED): Dr. Chiu and his team use a sensitive single-base epigenetic profiling technology to characterize epigenetic modifications in cancers for liquid biopsy-based biomarker discovery in cancer detection and monitoring. • UChicago Myeloma Epidemiology Study: In this clinic-based cohort study at the University of Chicago, Dr. Chiu and his team investigate lifestyle, diet, cytogenetics, genetics, and epigenetic modifications, particularly 5-hydroxymethylcytosine, implicated in the racial/ethnic disparities in the development and outcomes of multiple myeloma. • International Lymphoma Epidemiology Consortium (InterLymph) and AsiaLymph: Dr. Chiu is collaborating with a large group of multi-institute international investigators to investigate the role of environmental exposures and genetic factors in the development of lymphoid malignancies. One of the ongoing major multi-institute initiatives is the InterLymph Genome-Wide Association Study of Lymphoid Malignancies and Related Disorders. Dr. Chiu was also the principal investigator of Taiwan Center for the NCI AsiaLymph study to investigate the contribution of environmental, occupational, and genetic factors to lymphoma risk in Eastern Asia.
One or more keywords matched the following items that are connected to Chiu, Brian Chih-Hung
Item TypeName
Concept Treatment Outcome
Concept Biomedical Research
Concept Epidemiologic Research Design
Academic Article The challenges of epidemiologic research in non-Hodgkin lymphoma.
Academic Article InterLymph hierarchical classification of lymphoid neoplasms for epidemiologic research based on the WHO classification (2008): update and future directions.
Academic Article Long-term outcomes in patients with early stage nodular lymphocyte-predominant Hodgkin's lymphoma treated with radiotherapy.
Academic Article The impact of race, age, and sex in follicular lymphoma: A comprehensive SEER analysis across consecutive treatment eras.
Academic Article A systematic review of comparative schedule-related toxicities with maintenance rituximab in follicular and mantle cell lymphomas.
Academic Article Rationale and Design of the International Lymphoma Epidemiology Consortium (InterLymph) Non-Hodgkin Lymphoma Subtypes Project.
Academic Article The impact of race, ethnicity, age and sex on clinical outcome in chronic lymphocytic leukemia: a comprehensive Surveillance, Epidemiology, and End Results analysis in the modern era.
Academic Article Patterns of care and survival outcomes examining radiation therapy for advanced Hodgkin lymphoma.
Grant Illinois Precision Medicine Consortium (IPMC)
Academic Article Depressive symptoms, mental health-related quality of life, and survival among older patients with multiple myeloma.
Academic Article Racial differences in treatment and outcomes in multiple myeloma: a multiple myeloma research foundation analysis.
Academic Article Sex differences in outcomes in multiple myeloma.
Academic Article Evaluation of Frequency of Administration of Intravenous Bisphosphonate and Recurrent Skeletal-Related Events in Patients With Multiple Myeloma.
Grant ChicAgo Center for Health and EnvironmenT (CACHET)
Concept Patient Outcome Assessment
Grant Illinois Precision Medicine Consortium
Academic Article PETCH-DB: a Portal for Exploring Tissue-specific and Complex disease-associated 5-Hydroxymethylcytosines.
Academic Article PETCH-DB: a Portal for Exploring Tissue-specific and Complex disease-associated 5-Hydroxymethylcytosines.
Grant A highly sensitive linear amplification based DNA methylation profiling technique for clinical cancer research
Grant Risk of venous thromboembolism following diagnosis and treatment of multiple myeloma: differences by race
Grant Genome Wide Admixture Scan for Multiple Myeloma in African Americans
Grant Using epigenomic subtyping to understand the racial differences in lymphoma
Grant Postdoctoral Training Program in Cancer Epidemiology
Grant Impact of Lifestyle with Tumor Pathways and Microenvironment on Lymphoma Survival
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