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Ratain, Mark J.

One or more keywords matched the following items that are connected to Ratain, Mark J.

Item Type	Name
Concept	Pharmacogenetics
Academic Article	Individualizing dosing of cancer chemotherapy.
Academic Article	Individualized dosing of amonafide based on a pharmacodynamic model incorporating acetylator phenotype and gender.
Academic Article	Pharmacogenetics and cancer chemotherapy.
Academic Article	Pharmacogenetics in cancer etiology and chemotherapy.
Academic Article	Update on pharmacogenetics in cancer chemotherapy.
Academic Article	UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity.
Academic Article	Pharmacogenetics: a tool for individualizing antineoplastic therapy.
Academic Article	Phase I clinical and pharmacogenetic study of weekly TAS-103 in patients with advanced cancer.
Academic Article	Pharmacogenetics of anticancer agents: lessons from amonafide and irinotecan.
Academic Article	Pharmacogenetics in cancer treatment.
Academic Article	Pharmacogenomics: road to anticancer therapeutics nirvana?
Academic Article	Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups.
Academic Article	UGT pharmacogenomics: implications for cancer risk and cancer therapeutics.
Academic Article	Personalized medicine: building the GPS to take us there.
Academic Article	Hepatocyte nuclear factor-1 alpha is associated with UGT1A1, UGT1A9 and UGT2B7 mRNA expression in human liver.
Academic Article	From bedside to bench to bedside to clinical practice: an odyssey with irinotecan.
Academic Article	Pharmacogenomics: challenges and opportunities.
Academic Article	Irinogenetics: what is the right star?
Academic Article	Interpreting disparate responses to cancer therapy: the role of human population genetics.
Academic Article	Genetic nondiscrimination legislation: a critical prerequisite for pharmacogenomics data sharing.
Academic Article	The pharmacogenetics research network: from SNP discovery to clinical drug response.
Academic Article	Interpreting P values in pharmacogenetic studies: a call for process and perspective.
Academic Article	Pharmacogenomic and pharmacokinetic determinants of erlotinib toxicity.
Academic Article	Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans.
Academic Article	EGFR pharmacogenomics: the story continues to mutate and evolve.
Academic Article	Study of the genetic determinants of UGT1A1 inducibility by phenobarbital in cultured human hepatocytes.
Academic Article	Pharmacodynamic genes do not influence risk of neutropenia in cancer patients treated with moderately high-dose irinotecan.
Academic Article	The cancer and leukemia group B pharmacology and experimental therapeutics committee: a historical perspective.
Academic Article	A pharmacogenetic study of vorinostat glucuronidation.
Academic Article	Vascular endothelial growth factor pathway.
Academic Article	Cancer pharmacogenomics and pharmacoepidemiology: setting a research agenda to accelerate translation.
Academic Article	The 1200 patients project: creating a new medical model system for clinical implementation of pharmacogenomics.
Academic Article	Pharmacogenomics: will the promise be fulfilled?
Academic Article	TPMT, UGT1A1 and DPYD: genotyping to ensure safer cancer therapy?
Academic Article	Germline pharmacogenomics in oncology: decoding the patient for targeting therapy.
Academic Article	Pharmacogenomics and patient care: one size does not fit all.
Academic Article	The HapMap Resource is Providing New Insights into Ourselves and its Application to Pharmacogenomics.
Academic Article	Pharmacogenetics and pharmacogenomics of anticancer agents.
Academic Article	Drug-metabolizing enzymes: evidence for clinical utility of pharmacogenomic tests.
Academic Article	The role of pharmacogenetics in cancer therapeutics.
Academic Article	Pharmacogenetics of irinotecan: clinical perspectives on the utility of genotyping.
Academic Article	Pharmacogenetic pathway analysis of irinotecan.
Academic Article	Pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 polymorphisms: are we there yet?
Academic Article	Creating and evaluating genetic tests predictive of drug response.
Academic Article	Cancer pharmacogenomics: strategies and challenges.
Academic Article	A genome-wide integrative study of microRNAs in human liver.
Academic Article	Preclinical discovery of candidate genes to guide pharmacogenetics during phase I development: the example of the novel anticancer agent ABT-751.
Academic Article	The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance).
Academic Article	Meaningful use of pharmacogenetics.
Academic Article	Institutional Profile: University of Chicago Center for Personalized Therapeutics: research, education and implementation science.
Academic Article	Functional characterization of ABCC2 promoter polymorphisms and allele-specific expression.
Academic Article	Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance).
Academic Article	Adoption of a clinical pharmacogenomics implementation program during outpatient care--initial results of the University of Chicago "1,200 Patients Project".
Academic Article	Establishment of CYP2D6 reference samples by multiple validated genotyping platforms.
Academic Article	A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469.
Academic Article	Evidence for Clinical Implementation of Pharmacogenomics in Cardiac Drugs.
Academic Article	Participation in Cancer Pharmacogenomic Studies: A Study of 8456 Patients Registered to Clinical Trials in the Cancer and Leukemia Group B (Alliance).
Academic Article	Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing.
Academic Article	Clinical validity of new genetic biomarkers of irinotecan neutropenia: an independent replication study.
Academic Article	The Outlier in All of Us: Why Implementing Pharmacogenomics Could Matter for Everyone.
Academic Article	Disease-drug database for pharmacogenomic-based prescribing.
Academic Article	Genomewide Association Studies in Pharmacogenomics: Meeting Report of the NIH Pharmacogenomics Research Network-RIKEN (PGRN-RIKEN) Collaboration.
Academic Article	ABC transporter polymorphisms are associated with irinotecan pharmacokinetics and neutropenia.
Academic Article	Genome-wide association studies of drug response and toxicity: an opportunity for genome medicine.
Academic Article	Patient Perceptions of Care as Influenced by a Large Institutional Pharmacogenomic Implementation Program.
Academic Article	The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Outcomes and Metrics of Pharmacogenetic Implementations Across Diverse Healthcare Systems.
Academic Article	Cellular transporter pharmacogenetics in metastatic colorectal cancer: Initial analysis of C80203.
Academic Article	Pharmacogenomics-Based Point-of-Care Clinical Decision Support Significantly Alters Drug Prescribing.
Academic Article	Analyzing the clinical actionability of germline pharmacogenomic findings in oncology.
Academic Article	Essential Characteristics of Pharmacogenomics Study Publications.
Academic Article	A Pharmacogenetic Prediction Model of Progression-Free Survival in Breast Cancer using Genome-Wide Genotyping Data from CALGB 40502 (Alliance).
Academic Article	Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy.
Academic Article	Simplifying the use of pharmacogenomics in clinical practice: Building the genomic prescribing system.
Academic Article	Assessment of provider-perceived barriers to clinical use of pharmacogenomics during participation in an institutional implementation study.
Academic Article	Analysis of comprehensive pharmacogenomic profiling to impact in-hospital prescribing.
Academic Article	Patient-provider communications about pharmacogenomic results increase patient recall of medication changes.
Academic Article	Pharmacogenomic considerations for medications in the perioperative setting.
Academic Article	The ImPreSS Trial: Implementation of Point-of-Care Pharmacogenomic Decision Support in Perioperative Care.
Academic Article	Assessment of Patient Knowledge and Perceptions of Pharmacogenomics Before and After Using a Mock Results Patient Web Portal.
Academic Article	Pharmacogenomic genotypes define genetic ancestry in patients and enable population-specific genomic implementation.
Academic Article	Pharmacogenomic-Based Decision Support to Predict Adherence to Medications.
Academic Article	Genomewide Meta-Analysis Validates a Role for S1PR1 in Microtubule Targeting Agent-Induced Sensory Peripheral Neuropathy.
Academic Article	Patient insights on features of an effective pharmacogenomics patient portal.
Academic Article	Impact and applicability of pharmacogenomics in rheumatology: an integrated analysis.
Academic Article	Validation of a Large Custom-Designed Pharmacogenomics Panel on an Array Genotyping Platform.
Academic Article	Appraisal and development of evidence-based clinical decision support to enable perioperative pharmacogenomic application.
Academic Article	Impact of CYP2D6 Pharmacogenomic Status on Pain Control Among Opioid-Treated Oncology Patients.
Academic Article	Creation of a pharmacogenomics patient portal complementary to an existing institutional provider-facing clinical decision support system.
Academic Article	Anesthesia providers as stakeholders to adoption of pharmacogenomic information in perioperative care.
Academic Article	Underrepresented patient views and perceptions of personalized medication treatment through pharmacogenomics.
Academic Article	Clinically actionable genotypes for anticancer prescribing among >1500 patients with pharmacogenomic testing.
Academic Article	Pilot Findings of Pharmacogenomics in Perioperative Care: Initial Results From the First Phase of the ImPreSS Trial.
Academic Article	Implementation of pharmacogenomics into inpatient general medicine.
Academic Article	Pharmacogenetic and clinical risk factors for bevacizumab-related gastrointestinal hemorrhage in prostate cancer patients treated on CALGB 90401 (Alliance).

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Pharmacogenomics