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Ratain, Mark J.
One or more keywords matched the following items that are connected to Ratain, Mark J.
Item TypeName
Concept Protein-Tyrosine Kinases
Concept Protein Kinases
Concept Mitogen-Activated Protein Kinases
Concept Receptor Protein-Tyrosine Kinases
Concept Cyclin-Dependent Kinase Inhibitor p21
Concept Phosphotransferases
Concept Protein Kinase C
Concept Class I Phosphatidylinositol 3-Kinases
Concept TOR Serine-Threonine Kinases
Concept Cyclin-Dependent Kinase Inhibitor p15
Concept Cyclin-Dependent Kinases
Concept Phosphatidylinositol 3-Kinases
Concept MAP Kinase Signaling System
Concept Janus Kinase 2
Concept Ribosomal Protein S6 Kinases, 70-kDa
Concept Protein Kinase C-alpha
Concept Protein Kinase Inhibitors
Academic Article Flavopiridol metabolism in cancer patients is associated with the occurrence of diarrhea.
Academic Article Phase I clinical and pharmacokinetic study of protein kinase C-alpha antisense oligonucleotide ISIS 3521 administered in combination with 5-fluorouracil and leucovorin in patients with advanced cancer.
Academic Article Phase I clinical trial of CEP-2563 dihydrochloride, a receptor tyrosine kinase inhibitor, in patients with refractory solid tumors.
Academic Article Relationship of EGFR mutations, expression, amplification, and polymorphisms to epidermal growth factor receptor inhibitors in the NCI60 cell lines.
Academic Article Inflammation of actinic keratoses subsequent to therapy with sorafenib, a multitargeted tyrosine-kinase inhibitor.
Academic Article Terminal ballistics of kinase inhibitors: there are no magic bullets.
Academic Article Pharmacogenomic and pharmacokinetic determinants of erlotinib toxicity.
Academic Article Phase I trial of orally administered CEP-701, a novel neurotrophin receptor-linked tyrosine kinase inhibitor.
Academic Article Genomic assessment of a multikinase inhibitor, sorafenib, in a rodent model of pulmonary hypertension.
Academic Article Genome-wide identification of genetic determinants for the cytotoxicity of perifosine.
Academic Article A phase I trial to determine the safety, tolerability, and maximum tolerated dose of deforolimus in patients with advanced malignancies.
Academic Article EGFR pharmacogenomics: the story continues to mutate and evolve.
Academic Article A survey of the population genetic variation in the human kinome.
Academic Article Comparison of the drug-drug interactions potential of erlotinib and gefitinib via inhibition of UDP-glucuronosyltransferases.
Academic Article A dosing/cross-development study of the multikinase inhibitor sorafenib in patients with pulmonary arterial hypertension.
Academic Article A phase I study of sirolimus and bevacizumab in patients with advanced malignancies.
Academic Article A functional common polymorphism in a Sp1 recognition site of the epidermal growth factor receptor gene promoter.
Academic Article Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer.
Academic Article The UGT1A1*28 polymorphism correlates with erlotinib's effect on SN-38 glucuronidation.
Academic Article Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.
Academic Article Rapamycin: something old, something new, sometimes borrowed and now renewed.
Academic Article Inhibition of paracetamol glucuronidation by tyrosine kinase inhibitors.
Academic Article Phase I studies of sirolimus alone or in combination with pharmacokinetic modulators in advanced cancer patients.
Academic Article Playing Russian roulette with tyrosine kinase inhibitors.
Academic Article A novel fully automated molecular diagnostic system (AMDS) for colorectal cancer mutation detection.
Academic Article Preventing adverse drug-drug interactions: a need for improved data and logistics.
Academic Article A phase I and pharmacodynamic study of the histone deacetylase inhibitor belinostat plus azacitidine in advanced myeloid neoplasia.
Academic Article Vemurafenib oral bioavailability: an insoluble problem.
Academic Article Obviating the Need for Serial Biopsies Through Random Assignment.
Academic Article A phase I study of XL184, a RET, VEGFR2, and MET kinase inhibitor, in patients (pts) with advanced malignancies, including pts with medullary thyroid cancer (MTC).
Academic Article A pharmacodynamic study of sirolimus and metformin in patients with advanced solid tumors.
Academic Article Intraindividual Pharmacokinetic Variability: Focus on Small-Molecule Kinase Inhibitors.
Academic Article Clinical pharmacodynamic/exposure characterisation of the multikinase inhibitor ilorasertib (ABT-348) in a phase 1 dose-escalation trial.
Academic Article Influence of N-acetyltransferase 2 gene polymorphisms on the in vitro metabolism of the epidermal growth factor receptor inhibitor rociletinib.
Academic Article Subcutaneous Atezolizumab: A Jab Without a Benefit.
Academic Article Lorlatinib Exposed: A Far From Optimal Dose.
Academic Article The dosing of ibrutinib and related Bruton's tyrosine kinase inhibitors: eliminating the use of brute force.
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