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Hara, Manami

One or more keywords matched the following items that are connected to Hara, Manami

Item Type	Name
Concept	Diabetes Mellitus, Experimental
Concept	Diabetes Mellitus, Type 1
Concept	Diabetes Mellitus, Type 2
Concept	Insulin
Concept	Mutation
Concept	Insulin Resistance
Concept	Mutation, Missense
Concept	Insulin-Secreting Cells
Concept	Diabetes Mellitus
Academic Article	Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.
Academic Article	Mutations in the coding region of the insulin promoter factor 1 gene are not a common cause of maturity-onset diabetes of the young in Japanese subjects.
Academic Article	Beta-cell transcription factors and diabetes: mutations in the coding region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B) genes are not associated with maturity-onset diabetes of the young in Japanese.
Academic Article	Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymorphism in the PPARgamma gene.
Academic Article	Identification of three missense mutations in the peroxisome proliferator-activated receptor alpha gene in Japanese subjects with maturity-onset diabetes of the young.
Academic Article	No diabetes-associated mutations in the coding region of the hepatocyte nuclear factor-4gamma gene (HNF4G) in Japanese patients with MODY.
Academic Article	Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome.
Academic Article	Nestin-lineage cells contribute to the microvasculature but not endocrine cells of the islet.
Academic Article	A mouse model for studying intrahepatic islet transplantation.
Academic Article	Imaging endoplasmic reticulum calcium with a fluorescent biosensor in transgenic mice.
Academic Article	Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells.
Academic Article	The fusion of bone-marrow-derived proinsulin-expressing cells with nerve cells underlies diabetic neuropathy.
Academic Article	Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration.
Academic Article	Liver ischemia contributes to early islet failure following intraportal transplantation: benefits of liver ischemic-preconditioning.
Academic Article	Recovery of islet beta-cell function in streptozotocin- induced diabetic mice: an indirect role for the spleen.
Academic Article	Familial juvenile autoimmune hypothyroidism, pituitary enlargement, obesity, and insulin resistance.
Academic Article	Extrapancreatic insulin-producing cells in multiple organs in diabetes.
Academic Article	Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis.
Academic Article	Association of the (AU)AT-rich element polymorphism in PPP1R3 with hormonal and metabolic features of polycystic ovary syndrome.
Academic Article	No mantle formation in rodent islets -- the prototype of islet revisited.
Academic Article	Role of HNF-1alpha in regulating the expression of genes involved in cellular growth and proliferation in pancreatic beta-cells.
Academic Article	Insulin regulates islet alpha-cell function by reducing KATP channel sensitivity to adenosine 5'-triphosphate inhibition.
Academic Article	Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic a-cells in mouse models of ß-cell regeneration.
Academic Article	Characterization of an in vitro differentiation assay for pancreatic-like cell development from murine embryonic stem cells: detailed gene expression analysis.
Academic Article	Islet formation during the neonatal development in mice.
Academic Article	Altered islet composition and disproportionate loss of large islets in patients with type 2 diabetes.
Academic Article	Quantification of pancreatic islet distribution in situ in mice.
Academic Article	In situ quantification of pancreatic beta-cell mass in mice.
Academic Article	Islet architecture: A comparative study.
Academic Article	GSK-3 inactivation or depletion promotes ß-cell replication via down regulation of the CDK inhibitor, p27 (Kip1).
Academic Article	Quantification of islet size and architecture.
Academic Article	Generation of embryonic stem cells from mouse insulin I promoter-green fluorescent protein transgenic mice and characterization in a teratoma model.
Academic Article	Electrophysiological characterization of pancreatic islet cells in the mouse insulin promoter-green fluorescent protein mouse.
Academic Article	Imaging pancreatic beta-cells in the intact pancreas.
Academic Article	Glial cell line-derived neurotrophic factor increases beta-cell mass and improves glucose tolerance.
Academic Article	Quantitative analysis of pancreatic polypeptide cell distribution in the human pancreas.
Academic Article	Regional differences in islet distribution in the human pancreas--preferential beta-cell loss in the head region in patients with type 2 diabetes.
Academic Article	Distinct function of the head region of human pancreas in the pathogenesis of diabetes.
Academic Article	Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice.
Academic Article	Mathematical models of pancreatic islet size distributions.
Academic Article	Reduced Tyk2 gene expression in ß-cells due to natural mutation determines susceptibility to virus-induced diabetes.
Academic Article	Chronological analysis with fluorescent timer reveals unique features of newly generated ß-cells.
Academic Article	Systemic alterations in the metabolome of diabetic NOD mice delineate increased oxidative stress accompanied by reduced inflammation and hypertriglyceremia.
Academic Article	The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice.
Academic Article	Beta-cell destruction and preservation in childhood and adult onset type 1 diabetes.
Academic Article	The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans.
Academic Article	Design Principles of Pancreatic Islets: Glucose-Dependent Coordination of Hormone Pulses.
Academic Article	Adaptation of pancreatic islet cyto-architecture during development.
Academic Article	Tracing phenotypic reversibility of pancreatic ß-cells in vitro.
Academic Article	A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling.
Academic Article	Resting beta-cells - A functional reserve?
Academic Article	Dynamic recruitment of functionally distinct Swi/Snf chromatin remodeling complexes modulates Pdx1 activity in islet ß cells.
Academic Article	Diabetes Associated Metabolomic Perturbations in NOD Mice.
Academic Article	Preservation of Reduced Numbers of Insulin-Positive Cells in Sulfonylurea-Unresponsive KCNJ11-Related Diabetes.
Academic Article	Decrease in Ins+Glut2LO ß-cells with advancing age in mouse and human pancreas.
Academic Article	Three-Dimensional Analysis of the Human Pancreas.
Academic Article	Beta-cell hubs maintain Ca2+ oscillations in human and mouse islet simulations.
Academic Article	Quantitative analysis of intra- and inter-individual variability of human beta-cell mass.
Academic Article	Arsenic exposure induces glucose intolerance and alters global energy metabolism.
Academic Article	Pancreatic beta cell/islet mass and body mass index.
Academic Article	Heterogeneity of the Human Pancreatic Islet.
Academic Article	Developmental exposure to the endocrine disruptor tolylfluanid induces sex-specific later-life metabolic dysfunction.
Academic Article	The Local Paracrine Actions of the Pancreatic a-Cell.
Academic Article	Integrated Pancreatic Blood Flow: Bidirectional Microcirculation Between Endocrine and Exocrine Pancreas.
Academic Article	Pancreatic Islets and Gestalt Principles.
Academic Article	Implications of Integrated Pancreatic Microcirculation: Crosstalk between Endocrine and Exocrine Compartments.
Academic Article	Dynamin deficiency causes insulin secretion failure and hyperglycemia.
Grant	Quantitative analysis of aging in the human pancreas
Grant	Role of the environmental cues for beta-cell differentiation from ES cells
Academic Article	Erratum. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes 2023;72:433-448.
Academic Article	Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings.
Academic Article	Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings.
Academic Article	Geometric and topological characterization of the cytoarchitecture of islets of Langerhans.
Academic Article	Local Dialogues Between the Endocrine and Exocrine Cells in the Pancreas.

Search Criteria

Insulin
mutations
diabetes