Item Type | Name |
Concept
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Hypoxia, Brain
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Concept
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Hypoxia
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Concept
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Hypoxia-Inducible Factor 1, alpha Subunit
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Concept
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Hypoxia-Inducible Factor 1
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Concept
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Cell Hypoxia
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Concept
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Hypoxia-Ischemia, Brain
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Concept
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Fetal Hypoxia
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Academic Article
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Heterogeneity in cytosolic calcium responses to hypoxia in carotid body cells.
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Academic Article
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Cell selective induction and transcriptional activation of immediate early genes by hypoxia.
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Academic Article
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Possible genomic mechanism involved in control systems responses to hypoxia.
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Academic Article
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Regulation of neuronal nitric oxide synthase gene expression by hypoxia. Role of nitric oxide in respiratory adaptation to low pO2.
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Academic Article
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G proteins in carotid body chemoreception.
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Academic Article
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Carotid body I1-imidazoline receptors: binding, visualization and modulatory function.
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Academic Article
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Activation of nitric oxide synthase gene expression by hypoxia in central and peripheral neurons.
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Academic Article
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NO and CO as second messengers in oxygen sensing in the carotid body.
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Academic Article
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Nitric oxide and ventilatory response to hypoxia.
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Academic Article
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Involvement of substance P in neutral endopeptidase modulation of carotid body sensory responses to hypoxia.
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Academic Article
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Induction of immediate early response genes by hypoxia. Possible molecular bases for systems adaptation to low pO2.
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Academic Article
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Dual influence of nitric oxide on gene regulation during hypoxia.
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Academic Article
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Oxygen sensing by the carotid body chemoreceptors.
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Academic Article
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Intracellular pathways linking hypoxia to activation of c-fos and AP-1.
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Academic Article
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Release of dopamine and norepinephrine by hypoxia from PC-12 cells.
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Academic Article
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Endogenous carbon monoxide in control of respiration.
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Academic Article
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Role of substance P in neutral endopeptidase modulation of hypoxic response of the carotid body.
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Academic Article
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Role of c-fos in hypoxia-induced AP-1 cis-element activity and tyrosine hydroxylase gene expression.
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Academic Article
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Selected Contribution: Improved anoxic tolerance in rat diaphragm following intermittent hypoxia.
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Academic Article
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Neural drives and breathing stability.
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Academic Article
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Chronic intermittent hypoxia enhances carotid body chemoreceptor response to low oxygen.
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Academic Article
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Neurotransmitter release from the rabbit carotid body: differential effects of hypoxia on substance P and acetylcholine release.
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Academic Article
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Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha.
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Academic Article
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Sleep apneas: an oxidative stress?
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Academic Article
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Blunted respiratory responses to hypoxia in mutant mice deficient in nitric oxide synthase-3.
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Academic Article
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The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation.
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Academic Article
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Ventilatory changes during intermittent hypoxia: importance of pattern and duration.
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Academic Article
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Augmentation of L-type calcium current by hypoxia in rabbit carotid body glomus cells: evidence for a PKC-sensitive pathway.
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Academic Article
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Intermittent hypoxia: cell to system.
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Academic Article
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Oxygen sensing during intermittent hypoxia: cellular and molecular mechanisms.
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Academic Article
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Mutant mice deficient in NOS-1 exhibit attenuated long-term facilitation and short-term potentiation in breathing.
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Academic Article
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Tachykinins in the control of breathing by hypoxia: pre- and post-genomic era.
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Academic Article
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Gene regulation during intermittent hypoxia: evidence for the involvement of reactive oxygen species.
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Academic Article
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Reactive oxygen species in the plasticity of respiratory behavior elicited by chronic intermittent hypoxia.
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Academic Article
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Release of substance P by low oxygen in the rabbit carotid body: evidence for the involvement of calcium channels.
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Academic Article
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Systemic and cellular responses to intermittent hypoxia: evidence for oxidative stress and mitochondrial dysfunction.
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Academic Article
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Peripheral chemoreceptors in health and disease.
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Academic Article
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Oxidative stress in the systemic and cellular responses to intermittent hypoxia.
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Academic Article
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Entrainment pattern between sympathetic and phrenic nerve activities in the Sprague-Dawley rat: hypoxia-evoked sympathetic activity during expiration.
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Academic Article
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Hypoxia does not uniformly facilitate the release of multiple transmitters from the carotid body.
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Academic Article
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CO(2) and pH independently modulate L-type Ca(2+) current in rabbit carotid body glomus cells.
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Academic Article
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Intermittent hypoxia augments carotid body and ventilatory response to hypoxia in neonatal rat pups.
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Academic Article
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Detection of oxygen sensing during intermittent hypoxia.
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Academic Article
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Acetylcholine release from the carotid body by hypoxia: evidence for the involvement of autoinhibitory receptors.
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Academic Article
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Impaired ventilatory acclimatization to hypoxia in mice lacking the immediate early gene fos B.
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Academic Article
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Cellular and molecular mechanisms associated with carotid body adaptations to chronic hypoxia.
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Academic Article
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Secretion of brain-derived neurotrophic factor from PC12 cells in response to oxidative stress requires autocrine dopamine signaling.
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Academic Article
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Regulation of gene expression by HIF-1.
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Academic Article
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Systemic, cellular and molecular analysis of chemoreflex-mediated sympathoexcitation by chronic intermittent hypoxia.
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Academic Article
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Comparative analysis of neonatal and adult rat carotid body responses to chronic intermittent hypoxia.
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Academic Article
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Acute lung injury augments hypoxic ventilatory response in the absence of systemic hypoxemia.
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Academic Article
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Altered carotid body function by intermittent hypoxia in neonates and adults: relevance to recurrent apneas.
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Academic Article
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Heterozygous HIF-1alpha deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia.
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Academic Article
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ROS signaling in systemic and cellular responses to chronic intermittent hypoxia.
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Academic Article
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Increased secretory capacity of mouse adrenal chromaffin cells by chronic intermittent hypoxia: involvement of protein kinase C.
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Academic Article
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Induction of HIF-1alpha expression by intermittent hypoxia: involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR.
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Academic Article
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HIF-1-dependent respiratory, cardiovascular, and redox responses to chronic intermittent hypoxia.
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Academic Article
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Transcriptional responses to intermittent hypoxia.
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Academic Article
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Role of oxidative stress in intermittent hypoxia-induced immediate early gene activation in rat PC12 cells.
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Academic Article
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Intermittent hypoxia degrades HIF-2alpha via calpains resulting in oxidative stress: implications for recurrent apnea-induced morbidities.
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Academic Article
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Role of substance P in hypercapnic excitation of carotid chemoreceptors.
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Academic Article
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Intermittent hypoxia activates peptidylglycine alpha-amidating monooxygenase in rat brain stem via reactive oxygen species-mediated proteolytic processing.
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Academic Article
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Pattern-specific sustained activation of tyrosine hydroxylase by intermittent hypoxia: role of reactive oxygen species-dependent downregulation of protein phosphatase 2A and upregulation of protein kinases.
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Academic Article
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NADPH oxidase is required for the sensory plasticity of the carotid body by chronic intermittent hypoxia.
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Academic Article
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Hypoxia inhibits maturation and trafficking of hERG K(+) channel protein: Role of Hsp90 and ROS.
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Academic Article
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Redox Pioneer: Professor Gregg L. Semenza.
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Academic Article
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O2 sensing at the mammalian carotid body: why multiple O2 sensors and multiple transmitters?
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Academic Article
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Long-term regulation of carotid body function: acclimatization and adaptation--invited article.
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Academic Article
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Neonatal intermittent hypoxia leads to long-lasting facilitation of acute hypoxia-evoked catecholamine secretion from rat chromaffin cells.
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Academic Article
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H2S mediates O2 sensing in the carotid body.
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Academic Article
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Sensing hypoxia: carotid body mechanisms and reflexes in health and disease.
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Academic Article
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NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: relevance to blood pressure changes in rats.
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Academic Article
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NADPH oxidase-dependent regulation of T-type Ca2+ channels and ryanodine receptors mediate the augmented exocytosis of catecholamines from intermittent hypoxia-treated neonatal rat chromaffin cells.
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Academic Article
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Intermittent hypoxia augments acute hypoxic sensing via HIF-mediated ROS.
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Academic Article
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Cellular mechanisms associated with intermittent hypoxia.
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Academic Article
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Sensory plasticity of the carotid body: role of reactive oxygen species and physiological significance.
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Academic Article
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Sympatho-adrenal activation by chronic intermittent hypoxia.
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Academic Article
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The role of hypoxia-inducible factors in oxygen sensing by the carotid body.
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Academic Article
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Hydrogen sulfide (H(2)S): a physiologic mediator of carotid body response to hypoxia.
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Academic Article
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Post-translational modification of proteins during intermittent hypoxia.
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Academic Article
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Comparison of the effects of hypercapnia on phrenic and hypoglossal activity in anesthetized decerebrate and decorticate animals.
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Academic Article
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Oxygen sensing in the body.
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Academic Article
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Reactive oxygen species-dependent endothelin signaling is required for augmented hypoxic sensory response of the neonatal carotid body by intermittent hypoxia.
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Academic Article
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Analysis of carotid chemoreceptor responses to substance P analogue in anaesthetized cats.
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Academic Article
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Effect of arterial chemoreceptor stimulation: role of norepinephrine in hypoxic chemotransmission.
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Academic Article
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Inhibitory sympathetic action on the carotid body responses to sustained hypoxia.
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Academic Article
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Contrasting effects of intermittent and continuous hypoxia on low O(2) evoked catecholamine secretion from neonatal rat chromaffin cells.
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Academic Article
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Enhanced neuropeptide Y synthesis during intermittent hypoxia in the rat adrenal medulla: role of reactive oxygen species-dependent alterations in precursor peptide processing.
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Academic Article
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Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia.
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Academic Article
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Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis.
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Academic Article
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Chronic intermittent hypoxia induces hypoxia-evoked catecholamine efflux in adult rat adrenal medulla via oxidative stress.
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Academic Article
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Differential regulation of tyrosine hydroxylase by continuous and intermittent hypoxia.
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Academic Article
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Hypoxia-inducible factor 2a (HIF-2a) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension.
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Academic Article
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Analysis of postinspiratory activity of phrenic motoneurons with chemical and vagal reflexes.
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Academic Article
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Effect of substance P antagonist on the hypoxia-induced carotid chemoreceptor activity.
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Academic Article
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Endothelin-1 mediates attenuated carotid baroreceptor activity by intermittent hypoxia.
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Academic Article
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Gas biology: small molecular medicine.
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Academic Article
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Tachykinin antagonists in carotid body responses to hypoxia and substance P in the rat.
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Academic Article
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Acute intermittent hypoxia increases both phrenic and sympathetic nerve activities in the rat.
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Academic Article
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Novel role for reactive oxygen species as amplifiers of intermittent hypoxia. Focus on "Reactive oxygen species mediate central cardiorespiratory network responses to acute intermittent hypoxia".
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Academic Article
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Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2.
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Academic Article
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Low PO2 dependency of neutral endopeptidase and acetylcholinesterase activities of the rat carotid body.
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Academic Article
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Role of substance P in rat carotid body responses to hypoxia and capsaicin.
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Academic Article
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Selective blockade of sensory response of the carotid body to hypoxia by NK-1 receptor antagonist CP-96,345.
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Academic Article
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Selective inhibition of the carotid body sensory response to hypoxia by the substance P receptor antagonist CP-96,345.
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Academic Article
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Intermittent hypoxia-mediated plasticity of acute O2 sensing requires altered red-ox regulation by HIF-1 and HIF-2.
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Academic Article
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Post-translational modification of glutamic acid decarboxylase 67 by intermittent hypoxia: evidence for the involvement of dopamine D1 receptor signaling.
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Academic Article
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Carbon monoxide (CO) and hydrogen sulfide (H(2)S) in hypoxic sensing by the carotid body.
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Academic Article
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Endogenous H2S is required for hypoxic sensing by carotid body glomus cells.
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Academic Article
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Altered respiratory responses to hypoxia in mutant mice deficient in neuronal nitric oxide synthase.
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Academic Article
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L-type Ca(2+) channel activation regulates induction of c-fos transcription by hypoxia.
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Academic Article
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Chemosensing at the carotid body. Involvement of a HERG-like potassium current in glomus cells.
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Academic Article
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Peripheral chemosensitivity in mutant mice deficient in nitric oxide synthase.
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Academic Article
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Augmentation of calcium current by hypoxia in carotid body glomus cells.
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Academic Article
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Role of alpha 2-adrenergic receptors in the carotid body response to isocapnic hypoxia.
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Academic Article
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Role of nitric oxide in short-term potentiation and long-term facilitation: involvement of NO in breathing stability.
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Academic Article
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Activation of tyrosine hydroxylase by intermittent hypoxia: involvement of serine phosphorylation.
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Academic Article
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Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneas.
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Academic Article
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Facilitation of dopamine and acetylcholine release by intermittent hypoxia in PC12 cells: involvement of calcium and reactive oxygen species.
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Academic Article
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Effect of two paradigms of chronic intermittent hypoxia on carotid body sensory activity.
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Academic Article
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Ca2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia.
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Academic Article
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Modulation of the hypoxic sensory response of the carotid body by 5-hydroxytryptamine: role of the 5-HT2 receptor.
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Academic Article
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Kv1.1 deletion augments the afferent hypoxic chemosensory pathway and respiration.
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Academic Article
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Cardiovascular alterations by chronic intermittent hypoxia: importance of carotid body chemoreflexes.
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Academic Article
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Neonatal intermittent hypoxia impairs neuronal nicotinic receptor expression and function in adrenal chromaffin cells.
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Academic Article
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Mechanisms of sympathetic activation and blood pressure elevation by intermittent hypoxia.
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Academic Article
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Gaseous messengers in oxygen sensing.
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Academic Article
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Influence of adrenaline and hypoxia on rat muscle receptors in vitro.
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Academic Article
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Developmental programming of O(2) sensing by neonatal intermittent hypoxia via epigenetic mechanisms.
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Academic Article
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Sensing hypoxia: physiology, genetics and epigenetics.
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Academic Article
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Peripheral chemoreceptors: function and plasticity of the carotid body.
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Academic Article
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Mutual antagonism between hypoxia-inducible factors 1a and 2a regulates oxygen sensing and cardio-respiratory homeostasis.
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Academic Article
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Regulation of hypoxia-inducible factor-a isoforms and redox state by carotid body neural activity in rats.
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Academic Article
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Is insulin the new intermittent hypoxia?
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Academic Article
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Inherent variations in CO-H2S-mediated carotid body O2 sensing mediate hypertension and pulmonary edema.
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Academic Article
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Gasotransmitter regulation of ion channels: a key step in O2 sensing by the carotid body.
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Academic Article
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TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.
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Academic Article
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Hypoxia-inducible factors regulate human and rat cystathionine ß-synthase gene expression.
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Academic Article
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Impairment of pancreatic ß-cell function by chronic intermittent hypoxia.
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Academic Article
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CaV3.2 T-type Ca²? channels in H2S-mediated hypoxic response of the carotid body.
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Academic Article
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Intermittent hypoxia-induced endothelial barrier dysfunction requires ROS-dependent MAP kinase activation.
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Academic Article
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Xanthine oxidase mediates hypoxia-inducible factor-2a degradation by intermittent hypoxia.
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Academic Article
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Role of oxidative stress-induced endothelin-converting enzyme activity in the alteration of carotid body function by chronic intermittent hypoxia.
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Academic Article
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Hypoxia-inducible factors and hypertension: lessons from sleep apnea syndrome.
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Academic Article
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Neuromolecular mechanisms mediating the effects of chronic intermittent hypoxia on adrenal medulla.
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Academic Article
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Peripheral chemoreception and arterial pressure responses to intermittent hypoxia.
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Academic Article
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Protein kinase G-regulated production of H2S governs oxygen sensing.
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Academic Article
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HIF-1a activation by intermittent hypoxia requires NADPH oxidase stimulation by xanthine oxidase.
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Academic Article
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The human carotid body releases acetylcholine, ATP and cytokines during hypoxia.
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Academic Article
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Epigenetic Regulation of Carotid Body Oxygen Sensing: Clinical Implications.
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Academic Article
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Carotid Body Chemoreflex Mediates Intermittent Hypoxia-Induced Oxidative Stress in the Adrenal Medulla.
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Academic Article
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Oxygen Sensing and Homeostasis.
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Academic Article
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Neural regulation of hypoxia-inducible factors and redox state drives the pathogenesis of hypertension in a rodent model of sleep apnea.
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Academic Article
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Regulation of carotid body oxygen sensing by hypoxia-inducible factors.
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Academic Article
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CaV3.2 T-type Ca2+ channels mediate the augmented calcium influx in carotid body glomus cells by chronic intermittent hypoxia.
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Academic Article
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Calpain activation by ROS mediates human ether-a-go-go-related gene protein degradation by intermittent hypoxia.
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Academic Article
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Chronic Intermittent Hypoxia Alters Local Respiratory Circuit Function at the Level of the preBötzinger Complex.
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Academic Article
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Carotid body chemoreflex: a driver of autonomic abnormalities in sleep apnoea.
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Academic Article
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Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients.
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Academic Article
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Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long-term intermittent hypoxia.
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Academic Article
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HIF-1a is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium.
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Academic Article
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Oxygen Sensing by the Carotid Body: Past and Present.
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Academic Article
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Measurement of Sensory Nerve Activity from the Carotid Body.
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Academic Article
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Reactive oxygen radicals and gaseous transmitters in carotid body activation by intermittent hypoxia.
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Academic Article
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H2S mediates carotid body response to hypoxia but not anoxia.
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Academic Article
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The role of hypoxia-inducible factors in carotid body (patho) physiology.
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Academic Article
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DNA methylation in the central and efferent limbs of the chemoreflex requires carotid body neural activity.
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Academic Article
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Epigenetic changes by DNA methylation in chronic and intermittent hypoxia.
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Academic Article
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Recent advances in understanding the physiology of hypoxic sensing by the carotid body.
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Academic Article
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Hypoxia induced hERG trafficking defect linked to cell cycle arrest in SH-SY5Y cells.
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Grant
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Integrative Consequences of Intermittent Hypoxia
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Academic Article
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Long-term facilitation of catecholamine secretion from adrenal chromaffin cells of neonatal rats by chronic intermittent hypoxia.
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Academic Article
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Neural Activation of Molecular Circuitry in Intermittent Hypoxia.
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Academic Article
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2019 Nobel Prize in Physiology or Medicine.
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Academic Article
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Olfactory receptor 78 participates in carotid body response to a wide range of low O2 levels but not severe hypoxia.
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Academic Article
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Hypoxia-inducible factors and obstructive sleep apnea.
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Academic Article
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Hypoxia-inducible factor-1 mediates pancreatic ß-cell dysfunction by intermittent hypoxia.
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Academic Article
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Olfactory receptor 78 regulates erythropoietin and cardiorespiratory responses to hypobaric hypoxia.
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Academic Article
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Gaseous transmitter regulation of hypoxia-evoked catecholamine secretion from murine adrenal chromaffin cells.
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Academic Article
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Role of olfactory receptor78 in carotid body-dependent sympathetic activation and hypertension in murine models of chronic intermittent hypoxia.
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Academic Article
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Histone Deacetylase 5 Is an Early Epigenetic Regulator of Intermittent Hypoxia Induced Sympathetic Nerve Activation and Blood Pressure.
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Academic Article
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Lysine demethylase KDM6B regulates HIF-1a-mediated systemic and cellular responses to intermittent hypoxia.
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Academic Article
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Intermittent Hypoxia-Induced Activation of Endothelial Cells Is Mediated via Sympathetic Activation-Dependent Catecholamine Release.
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Academic Article
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Protein phosphatase 1 regulates reactive oxygen species-dependent degradation of histone deacetylase 5 by intermittent hypoxia.
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Academic Article
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Carotid body responses to O2 and CO2 in hypoxia-tolerant naked mole rats.
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Academic Article
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Adaptive cardiorespiratory changes to chronic continuous and intermittent hypoxia.
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Academic Article
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Intermittent hypoxia inhibits epinephrine-induced transcriptional changes in human aortic endothelial cells.
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Academic Article
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A pleiotropic hypoxia-sensitive EPAS1 enhancer is disrupted by adaptive alleles in Tibetans.
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Academic Article
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Carotid body hypersensitivity in intermittent hypoxia and obtructive sleep apnoea.
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Academic Article
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Hypoxia sensing requires H2S-dependent persulfidation of olfactory receptor 78.
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Academic Article
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Editorial: Vascular pathophysiology in hypoxia.
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Academic Article
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P300/CBP Regulates HIF-1-Dependent Sympathetic Activation and Hypertension by Intermittent Hypoxia.
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Academic Article
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Correction: Hypoxia induced hERG trafficking defect linked to cell cycle arrest in SH-SY5Y cells.
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Academic Article
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Transcriptomic Analysis of Postnatal Rat Carotid Body Development.
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