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Search Results to Mark A. Abney

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One or more keywords matched the following properties of Abney, Mark A.

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keywords Computational Biology
overview My research focus is on developing both new statistical methods and computational techniques to overcome the difficult problems in the analysis of genetic and genomic data. A primary interest is on developing models and approximations that are highly computationally efficient while leveraging as much of the information in the data as possible. As novel technologies are developed to collect ever larger and more specific genetic and genomic data, there arises a concurrent need for innovative methods to extract scientific insight from the data. My research focuses on developing such methods.

One or more keywords matched the following items that are connected to Abney, Mark A.

Item TypeName
Concept Models, Genetic
Concept Linear Models
Concept Models, Statistical
Concept Logistic Models
Academic Article Broad and narrow heritabilities of quantitative traits in a founder population.
Academic Article Quantitative-trait homozygosity and association mapping and empirical genomewide significance in large, complex pedigrees: fasting serum-insulin level in the Hutterites.
Academic Article The genetic dissection of complex traits in a founder population.
Academic Article Testing for Hardy-Weinberg equilibrium in samples with related individuals.
Academic Article Heritability estimation of sex-specific effects on human quantitative traits.
Academic Article GLOGS: a fast and powerful method for GWAS of binary traits with risk covariates in related populations.
Academic Article Genetic variance components estimation for binary traits using multiple related individuals.
Academic Article A graphical algorithm for fast computation of identity coefficients and generalized kinship coefficients.
Academic Article Genome-wide association studies and the problem of relatedness among advanced intercross lines and other highly recombinant populations.
Academic Article Identity by descent estimation with dense genome-wide genotype data.
Academic Article Estimation of variance components of quantitative traits in inbred populations.
Academic Article QTLRel: an R package for genome-wide association studies in which relatedness is a concern.
Academic Article Using identity by descent estimation with dense genotype data to detect positive selection.
Academic Article Practical considerations regarding the use of genotype and pedigree data to model relatedness in the context of genome-wide association studies.
Academic Article PRIMAL: Fast and accurate pedigree-based imputation from sequence data in a founder population.
Academic Article Permutation testing in the presence of polygenic variation.

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  • Computational
  • modeling