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One or more keywords matched the following properties of Kline, Justin P.
keywords Stem Cell Transplantation, Hematopoietic
keywords CAR T cell therapy
overview Dr. Kline is a medical oncologist who specializes in the treatment of patients with Hodgkin and non-Hodgkin lymphoma, including stem cell transplantation and CAR T cell therapy. He has expertise in the development and use of immunotherapy, and his lab research is focused on overcoming immune evasion pathways activated in blood cancers and on improving the effectiveness of immune-based treatments for people with lymphoma.
One or more keywords matched the following items that are connected to Kline, Justin P.
Item TypeName
Concept Combined Modality Therapy
Concept Drug Therapy, Combination
Concept Immune Tolerance
Concept Histocompatibility Testing
Concept Mice, Transgenic
Concept Neoplasm Transplantation
Concept Palliative Care
Concept Intensive Care Units
Concept Patient Care Team
Concept Preoperative Care
Concept Transcription Factors
Concept Respiratory Tract Infections
Concept Bone Marrow Transplantation
Concept Time Factors
Concept Tissue Donors
Concept Interferon Type I
Concept Terminal Care
Concept Hematopoietic Stem Cell Transplantation
Concept Tumor Cells, Cultured
Concept Salvage Therapy
Concept Stem Cell Transplantation
Concept T-Lymphocyte Subsets
Concept Treatment Outcome
Concept Guidelines as Topic
Concept Self Tolerance
Concept CD8-Positive T-Lymphocytes
Concept Transplantation Conditioning
Concept Basic-Leucine Zipper Transcription Factors
Concept Leukocyte Transfusion
Concept Peripheral Blood Stem Cell Transplantation
Concept Tumor Escape
Concept Adoptive Transfer
Concept STAT3 Transcription Factor
Concept Molecular Targeted Therapy
Concept Triazoles
Concept Treatment Failure
Concept Graft vs Tumor Effect
Concept T-Lymphocytes, Regulatory
Concept STAT1 Transcription Factor
Concept Cord Blood Stem Cell Transplantation
Concept Tumor Microenvironment
Concept Cell Line, Tumor
Concept Toll-Like Receptor 9
Concept fms-Like Tyrosine Kinase 3
Concept Standard of Care
Concept Clinical Trials as Topic
Concept Predictive Value of Tests
Concept Receptors, Antigen, T-Cell
Concept T-Lymphocytes
Concept Thymus Gland
Concept Translocation, Genetic
Concept Transplantation, Autologous
Concept Transplantation, Homologous
Concept Signal Transduction
Concept Leukemia, T-Cell
Concept Lymphoma, T-Cell, Peripheral
Concept Expressed Sequence Tags
Concept Maximum Tolerated Dose
Academic Article Pre-transplant ganciclovir and post transplant high-dose valacyclovir reduce CMV infections after alemtuzumab-based conditioning.
Academic Article Impact of disease burden at time of allogeneic stem cell transplantation in adults with acute myeloid leukemia and myelodysplastic syndromes.
Academic Article Homeostatic proliferation as an isolated variable reverses CD8+ T cell anergy and promotes tumor rejection.
Academic Article Gene expression profiles in acute myeloid leukemia with common translocations using SAGE.
Academic Article Nelarabine in the treatment of refractory T-cell malignant diseases.
Academic Article Autologous graft-versus-host disease: harnessing anti-tumor immunity through impaired self-tolerance.
Academic Article Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma.
Academic Article Allogeneic stem cell transplantation with alemtuzumab-based conditioning for patients with advanced chronic myelogenous leukemia.
Academic Article Will changing the face of WT1 make it more attractive to T cells?
Academic Article Immune resistance orchestrated by the tumor microenvironment.
Academic Article Costimulatory and coinhibitory receptors in anti-tumor immunity.
Academic Article Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions.
Academic Article Phase I-II study of clofarabine-melphalan-alemtuzumab conditioning for allogeneic hematopoietic cell transplantation.
Academic Article Clinical development of mAbs to block the PD1 pathway as an immunotherapy for cancer.
Academic Article Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells.
Academic Article Cellular and molecular requirements for rejection of B16 melanoma in the setting of regulatory T cell depletion and homeostatic proliferation.
Academic Article Clofarabine in the treatment of acute myeloid leukaemia and acute lymphoblastic leukaemia: a review.
Academic Article PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model.
Academic Article Phase II study of immunomodulation with granulocyte-macrophage colony-stimulating factor, interleukin-2, and rituximab following autologous stem cell transplant in patients with relapsed or refractory lymphomas.
Academic Article T-cell-depleted allogeneic transplant without donor leukocyte infusions results in excellent long-term survival in patients with multiply relapsed Lymphoma. Predictors for survival after transplant relapse.
Academic Article Molecular profiling to identify relevant immune resistance mechanisms in the tumor microenvironment.
Academic Article Influence of related donor age on outcomes after peripheral blood stem cell transplantation.
Academic Article CD40 ligation reverses T cell tolerance in acute myeloid leukemia.
Academic Article A dose-escalation study of recombinant human interleukin-18 in combination with rituximab in patients with non-Hodgkin lymphoma.
Academic Article Immune reconstitution after combined haploidentical and umbilical cord blood transplant.
Academic Article Therapeutic activity of high-dose intratumoral IFN-ß requires direct effect on the tumor vasculature.
Academic Article A phase I/II trial of bortezomib combined concurrently with gemcitabine for relapsed or refractory DLBCL and peripheral T-cell lymphomas.
Academic Article Leukemia cell-targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity.
Academic Article Targeting the innate immune system as immunotherapy for acute myeloid leukemia.
Academic Article Geriatric assessment to predict survival in older allogeneic hematopoietic cell transplantation recipients.
Academic Article PD-1 regulates extrathymic regulatory T-cell differentiation.
Academic Article Update on checkpoint blockade therapy for lymphoma.
Academic Article CD47 blockade triggers T cell-mediated destruction of immunogenic tumors.
Academic Article T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.
Academic Article Dendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells.
Academic Article Frequency and Risk Factors Associated with Cord Graft Failure after Transplant with Single-Unit Umbilical Cord Cells Supplemented by Haploidentical Cells with Reduced-Intensity Conditioning.
Academic Article MYC - a thorn in the side of cancer immunity.
Academic Article STING Pathway Activation Stimulates Potent Immunity against Acute Myeloid Leukemia.
Academic Article Incidence and predictors of respiratory viral infections by multiplex PCR in allogeneic hematopoietic cell transplant recipients 50 years and older including geriatric assessment.
Academic Article No Exit: Identifying Avoidable Terminal Oncology Intensive Care Unit Hospitalizations.
Academic Article Peripheral T-cell tolerance in hosts with acute myeloid leukemia.
Academic Article The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: multiple myeloma, lymphoma, and acute leukemia.
Academic Article Demonstration of ignition radiation temperatures in indirect-drive inertial confinement fusion hohlraums.
Academic Article Highly clonal regulatory T-cell population in follicular lymphoma - inverse correlation with the diversity of CD8+ T cells.
Academic Article PD-1 blockade induces remissions in relapsed classical Hodgkin lymphoma following allogeneic hematopoietic stem cell transplantation.
Academic Article Emerging role of checkpoint blockade therapy in lymphoma.
Academic Article Calreticulin promotes immunity and type I interferon-dependent survival in mice with acute myeloid leukemia.
Academic Article Mechanisms of Immune Tolerance in Leukemia and Lymphoma.
Academic Article Reduced-Intensity Allogeneic Transplant for Acute Myeloid Leukemia and Myelodysplastic Syndrome Using Combined CD34-Selected Haploidentical Graft and a Single Umbilical Cord Unit Compared with Matched Unrelated Donor Stem Cells in Older Adults.
Academic Article Combined Haploidentical and Umbilical Cord Blood Allogeneic Stem Cell Transplantation for High-Risk Lymphoma and Chronic Lymphoblastic Leukemia.
Academic Article Characterization of cancer comorbidity prior to allogeneic hematopoietic cell transplantation.
Academic Article Outcomes following second allogeneic stem cell transplant for disease relapse after T cell depleted transplant correlate with remission status and remission duration after the first transplant.
Academic Article Phase 1 study of lenalidomide plus dose-adjusted EPOCH-R in patients with aggressive B-cell lymphomas with deregulated MYC and BCL2.
Grant Homeostatic proliferation and regulatory T cell depletion as cancer immunotherapy
Grant Characterization of a T cell dysfunctional state induced in mice with AML
Academic Article Results from a multidisciplinary clinic guided by geriatric assessment before stem cell transplantation in older adults.
Academic Article Dose escalation prophylactic donor lymphocyte infusion after T-cell depleted matched related donor allogeneic hematopoietic cell transplantation is feasible and results in higher donor chimerism, faster immune re-constitution, and prolonged progression-free survival.
Academic Article Unexpected Toxicities When Nivolumab Was Given as Maintenance Therapy following Allogeneic Stem Cell Transplantation.
Academic Article Recommendations and outcomes from a geriatric assessment guided multidisciplinary clinic prior to autologous stem cell transplant in older patients.
Academic Article Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of lymphoma.
Academic Article The immune landscape and response to immune checkpoint blockade therapy in lymphoma.
Academic Article Gal9/Tim-3 expression level is higher in AML patients who fail chemotherapy.
Academic Article Primary resistance to CD19-directed chimeric antigen receptor T-cell therapy in T-cell/histiocyte-rich large B-cell lymphoma.
Academic Article A phase 1 trial utilizing TMI with fludarabine-melphalan in patients with hematologic malignancies undergoing second allo-SCT.
Concept Transplantation, Haploidentical
Concept Cell- and Tissue-Based Therapy
Concept Transplant Recipients
Search Criteria
  • CAR
  • T
  • cell therapy