Item Type | Name |
Concept
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Oxidative Phosphorylation
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Concept
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Phosphorylation
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Academic Article
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p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl.
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Academic Article
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Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line.
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Academic Article
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Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL).
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Academic Article
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The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells.
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Academic Article
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Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells.
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Academic Article
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Tyrosine phosphorylation of the product of the c-cbl protooncogene is [corrected] induced after integrin stimulation.
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Academic Article
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Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571.
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Academic Article
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The role of focal adhesion kinase binding in the regulation of tyrosine phosphorylation of paxillin.
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Academic Article
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Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells.
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Academic Article
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Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines.
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Academic Article
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Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells.
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Academic Article
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Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells.
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Academic Article
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Role of the cytoskeletal protein paxillin in oncogenesis.
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Academic Article
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Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer.
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Academic Article
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Activated c-Met signals through PI3K with dramatic effects on cytoskeletal functions in small cell lung cancer.
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Academic Article
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c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions.
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Academic Article
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Fibronectin enhances viability and alters cytoskeletal functions (with effects on the phosphatidylinositol 3-kinase pathway) in small cell lung cancer.
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Academic Article
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A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycin.
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Academic Article
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Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer.
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Academic Article
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Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells.
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Academic Article
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c-Met: structure, functions and potential for therapeutic inhibition.
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Academic Article
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Protein kinase C beta in malignant pleural mesothelioma.
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Academic Article
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Integrin-dependent protein tyrosine phosphorylation is a key regulatory event in collagen-IV-mediated adhesion and proliferation of human lung tumor cell line, Calu-1.
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Academic Article
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MET pathway as a therapeutic target.
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Academic Article
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Differential expression of RON in small and non-small cell lung cancers.
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Academic Article
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Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL.
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Academic Article
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MET and phosphorylated MET as potential biomarkers in lung cancer.
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Academic Article
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Factor independence of human myeloid leukemia cell lines is associated with increased phosphorylation of the proto-oncogene Raf-1.
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Academic Article
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CRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cells.
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Academic Article
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Shc phosphorylation in myeloid cells is regulated by granulocyte macrophage colony-stimulating factor, interleukin-3, and steel factor and is constitutively increased by p210BCR/ABL.
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Academic Article
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Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer.
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Academic Article
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Differential signaling after beta1 integrin ligation is mediated through binding of CRKL to p120(CBL) and p110(HEF1).
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Academic Article
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Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma.
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Academic Article
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A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase.
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Academic Article
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Expression patterns of PAX5, c-Met, and paxillin in neuroendocrine tumors of the lung.
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Academic Article
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Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL.
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Academic Article
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Lipopolysaccharide-induced phosphorylation of c-Met tyrosine residue 1003 regulates c-Met intracellular trafficking and lung epithelial barrier function.
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Academic Article
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MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma.
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Academic Article
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c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury.
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Academic Article
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Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer.
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Academic Article
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Role played by paxillin and paxillin tyrosine phosphorylation in hepatocyte growth factor/sphingosine-1-phosphate-mediated reactive oxygen species generation, lamellipodia formation, and endothelial barrier function.
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Academic Article
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Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.
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Academic Article
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Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL.
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Academic Article
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A pharmacodynamic study of sirolimus and metformin in patients with advanced solid tumors.
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Academic Article
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Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma.
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Academic Article
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The Mitochondrion as an Emerging Therapeutic Target in Cancer.
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Academic Article
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Effects of selected deubiquitinating enzyme inhibitors on the proliferation and motility of lung cancer and mesothelioma cell lines.
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Grant
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Role of Paxillin in Lung Cancer
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Grant
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Novel Targeted Therapy in Pancreatic Cancer
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Grant
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PAXILLIN--AN ONCOGENE ACTIVATED PROTEIN
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