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Search Results to Ravi Salgia

This is a "connection" page, showing the details of why an item matched the keywords from your search.

                     
                     

One or more keywords matched the following items that are connected to Salgia, Ravi

Item TypeName
Concept Protein-Tyrosine Kinases
Concept Protein Kinases
Concept Thymidine Kinase
Concept Phosphotransferases (Alcohol Group Acceptor)
Concept Mitogen-Activated Protein Kinases
Concept src-Family Kinases
Concept Receptor Protein-Tyrosine Kinases
Concept eIF-2 Kinase
Concept Janus Kinase 1
Concept Protein Kinase C-delta
Concept Mitogen-Activated Protein Kinase 3
Concept Mitogen-Activated Protein Kinase Kinases
Concept Cyclin-Dependent Kinase Inhibitor p21
Concept Focal Adhesion Protein-Tyrosine Kinases
Concept Focal Adhesion Kinase 1
Concept Protein Kinase C
Concept Class I Phosphatidylinositol 3-Kinases
Concept TOR Serine-Threonine Kinases
Concept MAP Kinase Kinase Kinase 1
Concept CDC2 Protein Kinase
Concept Protein-Serine-Threonine Kinases
Concept Mitogen-Activated Protein Kinase 1
Concept Phosphatidylinositol 3-Kinases
Concept MAP Kinase Signaling System
Concept JNK Mitogen-Activated Protein Kinases
Concept Janus Kinase 2
Concept Ribosomal Protein S6 Kinases, 70-kDa
Concept Cyclin-Dependent Kinase Inhibitor p27
Concept Protein Kinase C-alpha
Concept fms-Like Tyrosine Kinase 3
Concept Protein Kinase Inhibitors
Concept Focal Adhesion Kinase 2
Concept TYK2 Kinase
Academic Article p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl.
Academic Article Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line.
Academic Article Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL).
Academic Article Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL.
Academic Article BCR/ABL induces multiple abnormalities of cytoskeletal function.
Academic Article The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells.
Academic Article Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells.
Academic Article The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway.
Academic Article Role of focal adhesion proteins in signal transduction and oncogenesis.
Academic Article Thrombopoietin induces activation of the phosphatidylinositol-3' kinase pathway and formation of a complex containing p85PI3K and the protooncoprotein p120CBL.
Academic Article The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase.
Academic Article Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571.
Academic Article The role of focal adhesion kinase binding in the regulation of tyrosine phosphorylation of paxillin.
Academic Article The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells.
Academic Article Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells.
Academic Article Vascular endothelial growth factor-induced migration of multiple myeloma cells is associated with beta 1 integrin- and phosphatidylinositol 3-kinase-dependent PKC alpha activation.
Academic Article Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells.
Academic Article A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration.
Academic Article SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL.
Academic Article Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells.
Academic Article Cell motility, adhesion, homing, and migration assays in the studies of tyrosine kinases.
Academic Article Role of receptor tyrosine kinases in lung cancer.
Academic Article Activated c-Met signals through PI3K with dramatic effects on cytoskeletal functions in small cell lung cancer.
Academic Article Fibronectin enhances viability and alters cytoskeletal functions (with effects on the phosphatidylinositol 3-kinase pathway) in small cell lung cancer.
Academic Article Targeted molecules in small cell lung cancer.
Academic Article Therapeutic targeting of the receptor tyrosine kinase Met.
Academic Article A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycin.
Academic Article Modulation of c-Kit/SCF pathway leads to alterations in topoisomerase-I activity in small cell lung cancer.
Academic Article Epidermal growth factor receptor mutations and susceptibility to targeted therapy in lung cancer.
Academic Article c-Met inhibition.
Academic Article Phase I trial of erlotinib-based multimodality therapy for inoperable stage III non-small cell lung cancer.
Academic Article Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species.
Academic Article Protein kinase C beta in malignant pleural mesothelioma.
Academic Article EGFR-targeted therapeutics: focus on SCCHN and NSCLC.
Academic Article Biology and novel therapeutics for neuroendocrine tumors of the lung.
Academic Article Integrin-dependent protein tyrosine phosphorylation is a key regulatory event in collagen-IV-mediated adhesion and proliferation of human lung tumor cell line, Calu-1.
Academic Article The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma.
Academic Article Receptor tyrosine kinases and inhibitors in lung cancer.
Academic Article Role of c-Met in cancer: emphasis on lung cancer.
Academic Article EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation.
Academic Article Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma.
Academic Article PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene.
Academic Article MET receptor tyrosine kinase.
Academic Article Fyn: a novel molecular target in cancer.
Academic Article CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases.
Academic Article Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK translocation-positive patient with non-small cell lung cancer.
Academic Article Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin.
Academic Article Non-receptor tyrosine kinase inhibitors in lung cancer.
Academic Article FYN is overexpressed in human prostate cancer.
Academic Article Inhibition of MET receptor tyrosine kinase and its ligand hepatocyte growth factor.
Academic Article A novel classification of lung cancer into molecular subtypes.
Academic Article Overexpression of the µ-opioid receptor in human non-small cell lung cancer promotes Akt and mTOR activation, tumor growth, and metastasis.
Academic Article Differential expression of RON in small and non-small cell lung cancers.
Academic Article Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer.
Academic Article Therapeutic targeting of receptor tyrosine kinases in lung cancer.
Academic Article Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL.
Academic Article Melanoma proteoglycan modifies gene expression to stimulate tumor cell motility, growth, and epithelial-to-mesenchymal transition.
Academic Article Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.
Academic Article Factor independence of human myeloid leukemia cell lines is associated with increased phosphorylation of the proto-oncogene Raf-1.
Academic Article Role of protein kinase C ß and vascular endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans model organism.
Academic Article Phase 2 trial of Linifanib (ABT-869) in patients with advanced non-small cell lung cancer.
Academic Article Inhibition of MET receptor tyrosine kinase and its ligand hepatocyte growth factor.
Academic Article MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib.
Academic Article Tyrosine kinase mutations in human cancer.
Academic Article Sphingosine kinase 1 is required for mesothelioma cell proliferation: role of histone acetylation.
Academic Article c-Met is a potentially new therapeutic target for treatment of human melanoma.
Academic Article Shc phosphorylation in myeloid cells is regulated by granulocyte macrophage colony-stimulating factor, interleukin-3, and steel factor and is constitutively increased by p210BCR/ABL.
Academic Article The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases.
Academic Article Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism.
Academic Article NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases.
Academic Article Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis.
Academic Article Phase II study of the multitargeted tyrosine kinase inhibitor XL647 in patients with non-small-cell lung cancer.
Academic Article Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study.
Academic Article Targeting ALK: a promising strategy for the treatment of non-small cell lung cancer, non-Hodgkin's lymphoma, and neuroblastoma.
Academic Article A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase.
Academic Article Mechanisms of metastasis as related to receptor tyrosine kinases in small-cell lung cancer.
Academic Article Key signaling pathways and targets in lung cancer therapy.
Academic Article Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity.
Academic Article Novel targets for therapeutic agents in small cell lung cancer.
Academic Article The role of EGFR inhibition in the treatment of non-small cell lung cancer.
Academic Article RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma.
Academic Article Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification.
Academic Article Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL.
Academic Article Critical role for the receptor tyrosine kinase EPHB4 in esophageal cancers.
Academic Article The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target.
Academic Article A multicenter phase II study of ganetespib monotherapy in patients with genotypically defined advanced non-small cell lung cancer.
Academic Article Initial clinical sensitivity and acquired resistance to MET inhibition in MET-mutated papillary renal cell carcinoma.
Academic Article Lipopolysaccharide-induced phosphorylation of c-Met tyrosine residue 1003 regulates c-Met intracellular trafficking and lung epithelial barrier function.
Academic Article Transactivation of the receptor-tyrosine kinase ephrin receptor A2 is required for the low molecular weight hyaluronan-mediated angiogenesis that is implicated in tumor progression.
Academic Article Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells.
Academic Article Activating the expression of human K-rasG12D stimulates oncogenic transformation in transgenic goat fetal fibroblast cells.
Academic Article Expression of the EPHB4 receptor tyrosine kinase in head and neck and renal malignancies--implications for solid tumors and potential for therapeutic inhibition.
Academic Article MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma.
Academic Article Role of PAX8 in the regulation of MET and RON receptor tyrosine kinases in non-small cell lung cancer.
Academic Article Crizotinib in ROS1-rearranged non-small-cell lung cancer.
Academic Article Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides.
Academic Article Multiple Endocrine Disruption by the MET/ALK Inhibitor Crizotinib in Patients With Non-small Cell Lung Cancer.
Academic Article Dramatic antitumor effects of the dual MET/RON small-molecule inhibitor LY2801653 in non-small cell lung cancer.
Academic Article AXL mediates resistance to cetuximab therapy.
Academic Article Overcoming acquired resistance to cetuximab by dual targeting HER family receptors with antibody-based therapy.
Academic Article A safety assessment of crizotinib in the treatment of ALK-positive NSCLC patients.
Academic Article Nuclear epidermal growth factor receptor is a functional molecular target in triple-negative breast cancer.
Academic Article c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury.
Academic Article AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma.
Academic Article Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer.
Academic Article Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
Academic Article Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors.
Academic Article Phase II Study of the AKT Inhibitor MK-2206 plus Erlotinib in Patients with Advanced Non-Small Cell Lung Cancer Who Previously Progressed on Erlotinib.
Academic Article ROS1 rearranged non-small cell lung cancer brain metastases respond to low dose radiotherapy.
Academic Article C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype.
Academic Article Selumetinib with and without erlotinib in KRAS mutant and KRAS wild-type advanced nonsmall-cell lung cancer.
Academic Article Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer.
Academic Article 1330: Brigatinib efficacy and safety in patients (Pts) with anaplastic lymphoma kinase (ALK)-positive (ALK+) non-small cell lung cancer (NSCLC) in a phase 1/2 trial.
Academic Article Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
Academic Article Comprehensive Genomic Profiling Identifies a Subset of Crizotinib-Responsive ALK-Rearranged Non-Small Cell Lung Cancer Not Detected by Fluorescence In Situ Hybridization.
Academic Article Post-crizotinib management of effective ceritinib therapy in a patient with ALK-positive non-small cell lung cancer.
Academic Article FAK and paxillin, two potential targets in pancreatic cancer.
Academic Article Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.
Academic Article Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab.
Academic Article PI3 Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma.
Academic Article Activity and safety of brigatinib in ALK-rearranged non-small-cell lung cancer and other malignancies: a single-arm, open-label, phase 1/2 trial.
Academic Article The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor.
Academic Article TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.
Academic Article A phase I study of XL184, a RET, VEGFR2, and MET kinase inhibitor, in patients (pts) with advanced malignancies, including pts with medullary thyroid cancer (MTC).
Academic Article MET in Lung Cancer: Biomarker Selection Based on Scientific Rationale.
Academic Article The accelerated path of ceritinib: Translating pre-clinical development into clinical efficacy.
Academic Article Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.
Academic Article Effective osimertinib treatment in a patient with discordant T790 M mutation detection between liquid biopsy and tissue biopsy.
Academic Article Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL.
Academic Article A pharmacodynamic study of sirolimus and metformin in patients with advanced solid tumors.
Academic Article The brigatinib experience: a new generation of therapy for ALK-positive non-small-cell lung cancer.
Academic Article Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma.
Academic Article Responses to Alectinib in ALK-rearranged Papillary Renal Cell Carcinoma.
Academic Article Anaplastic Lymphoma Kinase (ALK)-positive Tumors: Clinical, Radiographic and Molecular Profiles, and Uncommon Sites of Metastases in Patients With Lung Adenocarcinoma.
Academic Article Synergistic efficacy of RLIP inhibition and 2'-hydroxyflavanone against DMBA-induced mammary carcinogenesis in SENCAR mice.
Academic Article Dose-escalation trial of the ALK, MET & ROS1 inhibitor, crizotinib, in patients with advanced cancer.
Academic Article Precision medicine and actionable alterations in lung cancer: A single institution experience.
Academic Article Radiomic prediction of mutation status based on MR imaging of lung cancer brain metastases.
Academic Article The promise of selective MET inhibitors in non-small cell lung cancer with MET exon 14 skipping.
Academic Article AXL Mediates Cetuximab and Radiation Resistance Through Tyrosine 821 and the c-ABL Kinase Pathway in Head and Neck Cancer.
Academic Article MET receptor in oncology: From biomarker to therapeutic target.
Academic Article Evaluation of Omics-Based Strategies for the Management of Advanced Lung Cancer.
Academic Article Hyperprogression on immunotherapy with complete response to chemotherapy in a NSCLC patient with high PD-L1 and STK11: A case report.
Academic Article Prolonged survival and response to tepotinib in a non-small-cell lung cancer patient with brain metastases harboring MET exon 14 mutation: a research report.
Academic Article Activating p53 function by targeting RLIP.

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