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One or more keywords matched the following items that are connected to Schilsky, Richard
Item TypeName
Concept Antineoplastic Agents
Concept Antineoplastic Agents, Hormonal
Concept Antineoplastic Agents, Phytogenic
Academic Article Phase I study of amonafide dosing based on acetylator phenotype.
Academic Article Statistical and ethical issues in the design and conduct of phase I and II clinical trials of new anticancer agents.
Academic Article Phase I clinical and pharmacology study of 502U83 given as a 24-h continuous intravenous infusion.
Academic Article Individualized dosing of amonafide based on a pharmacodynamic model incorporating acetylator phenotype and gender.
Academic Article Prospects for fertility after cancer chemotherapy.
Academic Article Phase I clinical and pharmacokinetic study of oral 9-aminocamptothecin (NSC-603071).
Academic Article Antifolates: the next generation.
Academic Article O6-benzylguanine in humans: metabolic, pharmacokinetic, and pharmacodynamic findings.
Academic Article Phase I and pharmacokinetic trial of paclitaxel in patients with hepatic dysfunction: Cancer and Leukemia Group B 9264.
Academic Article Phase I study of ZD9331 on short daily intravenous bolus infusion for 5 days every 3 weeks with fixed dosing recommendations.
Academic Article End points in cancer clinical trials and the drug approval process.
Academic Article Estimation of the effect of food on the disposition of oral 5-fluorouracil in combination with eniluracil.
Academic Article UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity.
Academic Article Pharmacology and clinical status of capecitabine.
Academic Article Antineoplastic drugs administered during pregnancy.
Academic Article Phase I clinical and pharmacogenetic study of weekly TAS-103 in patients with advanced cancer.
Academic Article Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer.
Academic Article Silence is golden: gene hypermethylation and survival in large-cell lymphoma.
Academic Article Paradoxical relationship between acetylator phenotype and amonafide toxicity.
Academic Article Hurry up and wait: is accelerated approval of new cancer drugs in the best interests of cancer patients?
Academic Article A phase I study of cantuzumab mertansine administered as a single intravenous infusion once weekly in patients with advanced solid tumors.
Academic Article Highlights from: 27th congress of the European Society for Medical Oncology. Nice, France. October 18-22, 2002.
Academic Article 3rd EORTC-NCI International Meeting on Cancer Molecular Markers: From Discovery to Clinical Practice.
Academic Article The Translational Research Working Group developmental pathway for anticancer agents (drugs or biologics).
Academic Article Biomarkers, surrogate end points, and the acceleration of drug development for cancer prevention and treatment: an update prologue.
Academic Article Are targeted therapies really targeted?
Academic Article Personalizing cancer care: American Society of Clinical Oncology presidential address 2009.
Academic Article The cancer and leukemia group B pharmacology and experimental therapeutics committee: a historical perspective.
Academic Article Refocusing the war on cancer: the critical role of personalized treatment.
Academic Article Personalized medicine in oncology: the future is now.
Academic Article A Cancer and Leukemia Group B phase II study of sunitinib malate in patients with previously treated metastatic pancreatic adenocarcinoma (CALGB 80603).
Academic Article Commentary: tackling the challenges of developing targeted therapies for cancer.
Academic Article Optimizing collection of adverse event data in cancer clinical trials supporting supplemental indications.
Academic Article Cancer pharmacogenomics and pharmacoepidemiology: setting a research agenda to accelerate translation.
Academic Article Male fertility following cancer chemotherapy.
Academic Article Pharmacokinetic modulation of oral etoposide by ketoconazole in patients with advanced cancer.
Academic Article Zoledronic acid preserves bone mineral density in premenopausal women who develop ovarian failure due to adjuvant chemotherapy: final results from CALGB trial 79809.
Academic Article How not to treat cancer.
Academic Article Chemotherapy for testicular cancer: current status of the National Cancer Institute Combined Modality Trial.
Academic Article Data submission standards and evidence requirements.
Academic Article Effects of cancer treatment on the reproductive system.
Academic Article Diagnosis, management, and evaluation of chemotherapy-induced peripheral neuropathy.
Academic Article GI cancers in 2010: New standards and a predictive biomarker for adjuvant therapy.
Academic Article Gonadal dysfunction in patients receiving chemotherapy for cancer.
Academic Article Renal and metabolic toxicities of cancer chemotherapy.
Academic Article Population pharmacodynamic study of amonafide: a Cancer and Leukemia Group B study.
Academic Article Phase I and pharmacokinetic study of a new antineoplastic agent: pyrazine diazohydroxide (NSC 361456).
Academic Article Phase I trial and pharmacokinetics of aziridinylbenzoquinone (NSC 182986) in humans.
Academic Article Cyclooxygenase-2 and cancer treatment: understanding the risk should be worth the reward.
Academic Article Etoposide combined with interferon alfa-2b: novel exploitation of established etoposide pharmacokinetics and pharmacodynamics.
Academic Article Ovarian function following radiation and chemotherapy for cancer.
Academic Article Long-term follow up of ovarian function in women treated with MOPP chemotherapy for Hodgkin's disease.
Academic Article Phase II study of amonafide in gastric adenocarcinoma. An Illinois Cancer Center trial.
Academic Article Phase II and pharmacodynamic studies of pyrazine diazohydroxide (NSC 361456) in patients with advanced renal and colorectal cancer.
Academic Article Modulation of vinblastine resistance in metastatic renal cell carcinoma with cyclosporine A or tamoxifen: a cancer and leukemia group B study.
Academic Article Phase I study of an oral formulation of ZD9331 administered daily for 28 days.
Academic Article A phase I trial of pharmacologic modulation of irinotecan with cyclosporine and phenobarbital.
Academic Article Phase I study of adozelesin administered by 24-hour continuous intravenous infusion.
Academic Article Target practice: oncology drug development in the era of genomic medicine.
Academic Article Pharmacodynamics in cancer therapy.
Academic Article An accelerated pathway for targeted cancer therapies.
Academic Article Role of randomized phase III trials in an era of effective targeted therapies.
Academic Article The role of high-dose therapy and autologous bone marrow reinfusion in the treatment of malignant lymphomas.
Academic Article Evaluation of food effect on pharmacokinetics of vismodegib in advanced solid tumor patients.
Academic Article Dose-finding and pharmacokinetic study to optimize the dosing of irinotecan according to the UGT1A1 genotype of patients with cancer.
Academic Article Clinical cancer advances 2015: Annual report on progress against cancer from the American Society of Clinical Oncology.
Academic Article Circadian variation in plasma 5-fluorouracil concentrations during a 24 hour constant-rate infusion.
Academic Article First-in-human, phase I study of elisidepsin (PM02734) administered as a 30-min or as a 3-hour intravenous infusion every three weeks in patients with advanced solid tumors.
Academic Article Effect of First-Line Chemotherapy Combined With Cetuximab or Bevacizumab on Overall Survival in Patients With KRAS Wild-Type Advanced or Metastatic Colorectal Cancer: A Randomized Clinical Trial.
Academic Article Precision cancer medicine: the future is now, only better.
Academic Article Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015.
Academic Article Biologic determinants of tumor recurrence in stage II colon cancer: validation study of the 12-gene recurrence score in cancer and leukemia group B (CALGB) 9581.
Academic Article Association of Biomarker-Based Treatment Strategies With Response Rates and Progression-Free Survival in Refractory Malignant Neoplasms: A Meta-analysis.
Academic Article Response.
Academic Article Implementing personalized cancer care.
Academic Article Hans Christian Andersen and the Value of New Cancer Treatments.
Academic Article Reevaluating the accelerated approval process for oncology drugs.
Academic Article Challenges in initiating and conducting personalized cancer therapy trials: perspectives from WINTHER, a Worldwide Innovative Network (WIN) Consortium trial.
Academic Article Moving from evaluation to value in cancer care.
Academic Article Impact of a Biomarker-Based Strategy on Oncology Drug Development: A Meta-analysis of Clinical Trials Leading to FDA Approval.
Academic Article Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015 Summary.
Academic Article Improving evidence developed from population-level experience with targeted agents.
Academic Article Streamlining Adverse Events Reporting in Oncology: An American Society of Clinical Oncology Research Statement.
Academic Article Accelerating anticancer drug development - opportunities and trade-offs.
Academic Article Impact of Precision Medicine in Diverse Cancers: A Meta-Analysis of Phase II Clinical Trials.
Academic Article Gains Against Cancer, But Enter 'Financial Toxicity'.
Academic Article American Society of Clinical Oncology Statement: Biosimilars in Oncology.
Academic Article Modernizing Eligibility Criteria for Molecularly Driven Trials.
Academic Article Comparative Assessment of Clinical Benefit Using the ESMO-Magnitude of Clinical Benefit Scale Version 1.1 and the ASCO Value Framework Net Health Benefit Score.
Academic Article Determining If a Somatic Tumor Mutation Is Targetable and Options for Accessing Targeted Therapies.
Academic Article The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs.
Academic Article Reply to M. Hutton-Potts and A.M. Joshua.
Academic Article Sunitinib in Patients with Metastatic Colorectal Cancer (mCRC) with FLT-3 Amplification: Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
Academic Article Cetuximab in Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Ovarian Cancer Without KRAS, NRAS, or BRAF Mutations: Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
Academic Article Pembrolizumab in Patients With Metastatic Breast Cancer With High Tumor Mutational Burden: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
Academic Article Cobimetinib Plus Vemurafenib in Patients With Colorectal Cancer With BRAF Mutations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
Academic Article Olaparib in Patients With Metastatic Prostate Cancer With BRCA1/2 Mutation: Results From the TAPUR Study.
Concept Antineoplastic Agents, Immunological
Grant CANCER AND LEUKEMIA GROUP B--PET COMMITTEE
Academic Article Pertuzumab Plus Trastuzumab in Patients With Lung Cancer With ERBB2 Mutation or Amplification: Results From the Targeted Agent and Profiling Utilization Registry Study.
Academic Article Pembrolizumab in Patients With Tumors With High Tumor Mutational Burden: Results From the Targeted Agent and Profiling Utilization Registry Study.
Academic Article Nivolumab Plus Ipilimumab in Patients With Solid Tumors With ATM Mutations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
Academic Article Cobimetinib Plus Vemurafenib in Patients With Solid Tumors With BRAF Mutations: Results From the Targeted Agent and Profiling Utilization Registry Study.
Academic Article Sunitinib in Patients With Breast Cancer With FGFR1 or FGFR2 Amplifications or Mutations: Results From the Targeted Agent and Profiling Utilization Registry Study.
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  • Antineoplastic Agents