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Search Results to Steven White

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One or more keywords matched the following properties of White, Steven

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keywords Airway epithelial cell biology
overview I have 30 years of experience in the study of asthma, airways inflammation and airways remodeling, with a focus to understand why inflammation persists and why repair is aberrant in airways. My focus in recent years has been on the initial response to airway injury in cell biology-focused studies. Along with this, I have focused on understanding clinical parameters important to the care of patients with asthma. I have successfully administered several major NIH-funded grants, all of which have required significant collaborations with investigators from diverse fields and which have generated peer-reviewed publications in key biomedical journals. More recently, I have focused on understanding clinical parameters important to the care of patients with asthma. I was contact PI in a U19 funded Asthma and Allergic Diseases Cooperative Research Center funded by NIAID. Our asthma program was just awarded a UG1 for precision medicine in severe and exacerbation prone asthma (the “PrecISE” protocol). I also co-direct our hospital-wide COPD clinical program that focuses on readmissions and the transitions from hospital to outpatient and community medicine. Our multi-disciplinary group has already “bent the curve” downward substantially in readmissions, and I direct the clinical support team that provides direct patient care. More recent work from our program examines the role of the epithelium in host-defense responses to the airway microbiome; we have the largest single-center study to state and currently are examining the relationship of the fungal microbiome (the ‘mycobiome’) to the bacterial microbiome in asthma. All of this is dedicated to the idea that understanding the basic and translational science of the lungs will lead to better therapies for asthma.

One or more keywords matched the following items that are connected to White, Steven

Item TypeName
Concept Epithelial Cells
Academic Article Migration of guinea pig airway epithelial cells in response to bombesin analogues.
Academic Article Characterization of cell surface lectin-binding patterns of human airway epithelium.
Academic Article Topographic distribution of prostaglandin secretion caused by bradykinin in canine tracheal epithelial cells.
Academic Article Airway epithelial cell wound repair mediated by alpha-dystroglycan.
Academic Article Role of very late adhesion integrins in mediating repair of human airway epithelial cell monolayers after mechanical injury.
Academic Article Expression of Fas (CD95) and FasL (CD95L) in human airway epithelium.
Academic Article Initiation of apoptosis by actin cytoskeletal derangement in human airway epithelial cells.
Academic Article Beta-adrenergic agonists inhibit corticosteroid-induced apoptosis of airway epithelial cells.
Academic Article Rho kinase inhibition initiates apoptosis in human airway epithelial cells.
Academic Article Corticosteroid-induced apoptosis in mouse airway epithelium: effect in normal airways and after allergen-induced airway inflammation.
Academic Article Expression of IL-4/IL-13 receptors in differentiating human airway epithelial cells.
Academic Article Epithelium-dependent contraction of airway smooth muscle caused by eosinophil MBP.
Academic Article Differentiated transplant derived airway epithelial cell cytokine secretion is not regulated by cyclosporine.
Academic Article Insulin receptor substrate-1/2 mediates IL-4-induced migration of human airway epithelial cells.
Academic Article Migration and proliferation of guinea pig and human airway epithelial cells in response to tachykinins.
Academic Article Proliferation of guinea pig tracheal epithelial cells induced by calcitonin gene-related peptide.
Academic Article Proliferation of guinea pig tracheal epithelial cells in coculture with rat dorsal root ganglion neural cells.
Academic Article Stimulation of migration and wound repair of guinea-pig airway epithelial cells in response to epidermal growth factor.
Academic Article Migration of human and guinea pig airway epithelial cells in response to calcitonin gene-related peptide.
Academic Article Prostaglandin secretion by guinea pig tracheal epithelial cells caused by eosinophil major basic protein.
Academic Article Stress-activated protein kinases mediate cell migration in human airway epithelial cells.
Academic Article Human leukocyte antigen-G expression in differentiated human airway epithelial cells: lack of modulation by Th2-associated cytokines.
Academic Article Interleukin-1beta mediates human airway epithelial cell migration via NF-kappaB.
Academic Article Smad and p38-MAPK signaling mediates apoptotic effects of transforming growth factor-beta1 in human airway epithelial cells.
Academic Article Cyclic mechanical stretch decreases cell migration by inhibiting phosphatidylinositol 3-kinase- and focal adhesion kinase-mediated JNK1 activation.
Academic Article Mechanical stretch decreases FAK phosphorylation and reduces cell migration through loss of JIP3-induced JNK phosphorylation in airway epithelial cells.
Academic Article Interleukin-1 receptor-associated kinase M (IRAK-M) promotes human rhinovirus infection in lung epithelial cells via the autophagic pathway.
Academic Article Peripheral blood IRF1 expression as a marker for glucocorticoid sensitivity.

Search Criteria
  • Airway
  • epithelial cell
  • biology