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Search Results to Steven White

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One or more keywords matched the following properties of White, Steven

keywords Asthma
overview I have 30 years of experience in the study of asthma, airways inflammation and airways remodeling, with a focus to understand why inflammation persists and why repair is aberrant in airways. My focus in recent years has been on the initial response to airway injury in cell biology-focused studies. Along with this, I have focused on understanding clinical parameters important to the care of patients with asthma. I have successfully administered several major NIH-funded grants, all of which have required significant collaborations with investigators from diverse fields and which have generated peer-reviewed publications in key biomedical journals. More recently, I have focused on understanding clinical parameters important to the care of patients with asthma. I was contact PI in a U19 funded Asthma and Allergic Diseases Cooperative Research Center funded by NIAID. Our asthma program was just awarded a UG1 for precision medicine in severe and exacerbation prone asthma (the “PrecISE” protocol). I also co-direct our hospital-wide COPD clinical program that focuses on readmissions and the transitions from hospital to outpatient and community medicine. Our multi-disciplinary group has already “bent the curve” downward substantially in readmissions, and I direct the clinical support team that provides direct patient care. More recent work from our program examines the role of the epithelium in host-defense responses to the airway microbiome; we have the largest single-center study to state and currently are examining the relationship of the fungal microbiome (the ‘mycobiome’) to the bacterial microbiome in asthma. All of this is dedicated to the idea that understanding the basic and translational science of the lungs will lead to better therapies for asthma.

One or more keywords matched the following items that are connected to White, Steven

Item TypeName
Concept Severity of Illness Index
Academic Article Secondary diagnoses as predictive factors for survival or mortality in Medicare patients with acute pneumonia.
Academic Article Activated eosinophils elicit substance P release from cultured dorsal root ganglion neurons.
Academic Article Corticosteroid-induced apoptosis of airway epithelium: a potential mechanism for chronic airway epithelial damage in asthma.
Academic Article Corticosteroid-induced apoptosis in mouse airway epithelium: effect in normal airways and after allergen-induced airway inflammation.
Academic Article Human leucocyte antigen-G: expression and function in airway allergic disease.
Academic Article Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21.
Academic Article Safety and feasibility of bronchial thermoplasty in asthma patients with very severe fixed airflow obstruction: a case series.
Academic Article Interleukin-1beta mediates human airway epithelial cell migration via NF-kappaB.
Academic Article Maternal asthma and microRNA regulation of soluble HLA-G in the airway.
Academic Article Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial.
Academic Article A genome-wide survey of CD4(+) lymphocyte regulatory genetic variants identifies novel asthma genes.
Academic Article Genome-wide interrogation of longitudinal FEV1 in children with asthma.
Academic Article Bronchial thermoplasty failure in severe persistent asthma: a case report.
Academic Article Airway Inflammation after Bronchial Thermoplasty for Severe Asthma.
Academic Article Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways.
Academic Article Virtual Teach-To-Goal™ Adaptive Learning of Inhaler Technique for Inpatients with Asthma or COPD.
Academic Article Elevated levels of soluble humanleukocyte antigen-G in the airways are a marker for a low-inflammatory endotype of asthma.
Academic Article Evidence for an IL-6-high asthma phenotype in asthmatic patients of African ancestry.

Search Criteria
  • severe
  • asthma