| Item Type | Name |
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Concept
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Leukemia
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Concept
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Leukemia, Lymphoid
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Concept
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Leukemia, Lymphocytic, Chronic, B-Cell
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Concept
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Leukemia, Myeloid
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Concept
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Leukemia, Myelomonocytic, Acute
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Concept
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Leukemia, Myeloid, Acute
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Concept
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Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
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Concept
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Leukemia, Promyelocytic, Acute
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Concept
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Leukemia-Lymphoma, Adult T-Cell
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Concept
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Leukemia, Myeloid, Chronic-Phase
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Concept
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Precursor Cell Lymphoblastic Leukemia-Lymphoma
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Concept
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Myeloid-Lymphoid Leukemia Protein
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Concept
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Leukemia, Monocytic, Acute
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Concept
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive
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Academic Article
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Analysis of the t(6;11)(q27;q23) in leukemia shows a consistent breakpoint in AF6 in three patients and in the ML-2 cell line.
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Academic Article
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Therapy-related myeloid leukemia.
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Academic Article
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Bronchiolitis obliterans organizing pneumonia as a complication of allogeneic bone marrow transplantation.
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Academic Article
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Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites.
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Academic Article
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Developmental analysis and subcellular localization of the murine homologue of ELL.
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Academic Article
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Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia.
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Academic Article
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Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice.
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Academic Article
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ELL and EAF1 are Cajal body components that are disrupted in MLL-ELL leukemia.
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Academic Article
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ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties.
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Academic Article
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The elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesis.
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Academic Article
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The elongation factor ELL (eleven-nineteen lysine-rich leukemia) is a selective coregulator for steroid receptor functions.
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Academic Article
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Methylation-independent silencing of the tumor suppressor INK4b (p15) by CBFbeta-SMMHC in acute myelogenous leukemia with inv(16).
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Academic Article
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Successful autologous stem cell collection in patients with chronic myeloid leukemia in complete cytogenetic response, with quantitative measurement of BCR-ABL expression in blood, marrow, and apheresis products.
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Academic Article
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Loss of MLL PHD finger 3 is necessary for MLL-ENL-induced hematopoietic stem cell immortalization.
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Academic Article
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Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.
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Academic Article
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High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML).
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Academic Article
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Gene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet?
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Academic Article
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Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia.
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Academic Article
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Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II.
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Academic Article
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Heterogeneity of breakpoints of 11q23 rearrangements in hematologic malignancies identified with fluorescence in situ hybridization.
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Academic Article
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DNA rearrangements and altered transcripts of the MLL gene in a human T-ALL cell line Karpas 45 with a t(X;11) (q13;q23) translocation.
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Academic Article
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A t(11;12) 11q23 leukemic breakpoint that disrupts the MLL gene.
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Academic Article
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The human MLL gene: nucleotide sequence, homology to the Drosophila trx zinc-finger domain, and alternative splicing.
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Academic Article
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Detection of MLL gene rearrangements in adult acute lymphoblastic leukemia. A Cancer and Leukemia Group B study.
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Academic Article
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Molecular analysis of the T-cell acute lymphoblastic leukemia-associated t(1;7)(p34;q34) that fuses LCK and TCRB.
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Academic Article
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Abnormalities of chromosome band 11q23 and the MLL gene in pediatric myelomonocytic and monoblastic leukemias. Identification of the t(9;11) as an indicator of long survival.
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Academic Article
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Do terminal deletions of 11q23 exist? Identification of undetected translocations with fluorescence in situ hybridization.
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Academic Article
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Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias.
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Academic Article
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Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia.
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Academic Article
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Detection of 11q23/MLL rearrangements in infant leukemias with fluorescence in situ hybridization and molecular analysis.
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Academic Article
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Cloning of cDNAs of the MLL gene that detect DNA rearrangements and altered RNA transcripts in human leukemic cells with 11q23 translocations.
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Academic Article
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EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein.
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Academic Article
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Fludarabine, melphalan, and alemtuzumab conditioning in adults with standard-risk advanced acute myeloid leukemia and myelodysplastic syndrome.
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Academic Article
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MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome.
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Academic Article
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Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations.
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Academic Article
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A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes.
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Academic Article
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Regulation of MEIS1 by distal enhancer elements in acute leukemia.
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Academic Article
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Ibrutinib for patients with relapsed or refractory chronic lymphocytic leukaemia with 17p deletion (RESONATE-17): a phase 2, open-label, multicentre study.
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Academic Article
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Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic Leukemia.
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Academic Article
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Efficacy of single-agent decitabine in relapsed and refractory acute myeloid leukemia.
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Academic Article
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Paradoxical Effects of MLL Paralogs in MLL-Rearranged Leukemia.
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Academic Article
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The full transforming capacity of MLL-Af4 is interlinked with lymphoid lineage commitment.
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Academic Article
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Treatment of Acute Promyelocytic Leukemia in Adults.
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Academic Article
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Quercetin Therapy for Selected Patients with PIM1 Kinase-Positive Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Pilot Study.
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Academic Article
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Clonal evolution underlying leukemia progression and Richter transformation in patients with ibrutinib-relapsed CLL.
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Academic Article
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A phase I study of selinexor in combination with high-dose cytarabine and mitoxantrone for remission induction in patients with acute myeloid leukemia.
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Academic Article
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Lenalidomide consolidation benefits patients with CLL receiving chemoimmunotherapy: results for CALGB 10404 (Alliance).
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Academic Article
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Safety and preliminary efficacy of venetoclax with decitabine or azacitidine in elderly patients with previously untreated acute myeloid leukaemia: a non-randomised, open-label, phase 1b study.
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Academic Article
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Entospletinib monotherapy in patients with relapsed or refractory chronic lymphocytic leukemia previously treated with B-cell receptor inhibitors: results of a phase 2 study.
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Academic Article
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A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia.
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Academic Article
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Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia.
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Academic Article
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Venetoclax with azacitidine or decitabine in patients with newly diagnosed acute myeloid leukemia: Long term follow-up from a phase 1b study.
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Academic Article
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Measurable Residual Disease Response and Prognosis in Treatment-Naïve Acute Myeloid Leukemia With Venetoclax and Azacitidine.
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Academic Article
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Impact of FLT3 Mutation on Outcomes after Venetoclax and Azacitidine for Patients with Treatment-Naïve Acute Myeloid Leukemia.
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Academic Article
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Efficacy and tolerability of a modified pediatric-inspired intensive regimen for acute lymphoblastic leukemia in older adults.
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Academic Article
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Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia.
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Academic Article
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Clinical and molecular response of acute myeloid leukemia harboring non-canonical FLT3 N676K driver mutations to contemporary FLT3 inhibitors.
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Academic Article
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The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia.
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Academic Article
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Socioeconomic determinants of the biology and outcomes of acute lymphoblastic leukemia in adults.
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Academic Article
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Long-term follow-up of VIALE-A: Venetoclax and azacitidine in chemotherapy-ineligible untreated acute myeloid leukemia.
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