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Search Results to Kenneth S. Polonsky

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One or more keywords matched the following items that are connected to Polonsky, Kenneth

Item TypeName
Concept Diabetes Mellitus, Type 1
Concept Diabetes Mellitus, Type 2
Academic Article Preservation of insulin secretory responses to P2 purinoceptor agonists in Zucker diabetic fatty rats.
Academic Article Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance.
Academic Article Plasma insulin, C-peptide, and proinsulin concentrations in obese and nonobese individuals with varying degrees of glucose tolerance.
Academic Article Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNALeu(UUR) gene mutation.
Academic Article Abnormalities of insulin pulsatility and glucose oscillations during meals in obese noninsulin-dependent diabetic patients: effects of weight reduction.
Academic Article NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity.
Academic Article Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats.
Academic Article Elevated plasma glucose 2 h postchallenge predicts defects in beta-cell function.
Academic Article Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
Academic Article Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12.
Academic Article Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats.
Academic Article Prevention of hyperglycemia in the Zucker diabetic fatty rat by treatment with metformin or troglitazone.
Academic Article Maturity onset diabetes of the young (MODY).
Academic Article Alternative insulin delivery systems: how demanding should the patient be?
Academic Article Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial.
Academic Article Interactions between insulin resistance and insulin secretion in the development of glucose intolerance.
Academic Article Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat.
Academic Article Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.
Academic Article The pancreatic beta cell heats up: UCP2 and insulin secretion in diabetes.
Academic Article Glucagon-like peptide 1 improves the ability of the beta-cell to sense and respond to glucose in subjects with impaired glucose tolerance.
Academic Article Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse.
Academic Article Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes.
Academic Article Evolution of beta-cell dysfunction in impaired glucose tolerance and diabetes.
Academic Article Abnormalities in the ultradian oscillations of insulin secretion and glucose levels in type 2 (non-insulin-dependent) diabetic patients.
Academic Article Dynamics of insulin secretion in obesity and diabetes.
Academic Article Glucagon-like peptide-1 stimulates insulin secretion by a Ca2+-independent mechanism in Zucker diabetic fatty rat islets of Langerhans.
Academic Article Roles of circadian rhythmicity and sleep in human glucose regulation.
Academic Article Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.
Academic Article Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance.
Academic Article Low acute insulin secretory responses in adult offspring of people with early onset type 2 diabetes.
Academic Article Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha.
Academic Article Temporal profiles and clinical significance of pulsatile insulin secretion.
Academic Article Hypoglycemic thresholds for cognitive dysfunction in IDDM.
Academic Article Insulin release in impaired glucose tolerance: oral minimal model predicts normal sensitivity to glucose but defective response times.
Academic Article Diabetes mellitus and genetically programmed defects in beta-cell function.
Academic Article Ginseng berry reduces blood glucose and body weight in db/db mice.
Academic Article C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001.
Academic Article Fasting hypertriglyceridemia in noninsulin-dependent diabetes mellitus is an important predictor of postprandial lipid and lipoprotein abnormalities.
Academic Article Nocturnal elevation of glucose levels during fasting in noninsulin-dependent diabetes.
Academic Article Effects of weight loss and reduced hyperglycemia on the kinetics of insulin secretion in obese non-insulin dependent diabetes mellitus.
Academic Article Effect of temporal distribution of calories on diurnal patterns of glucose levels and insulin secretion in NIDDM.
Academic Article Diabetic pancreatic beta cells ARNT all they should be.
Academic Article Postprandial triglyceride response in type 1 (insulin-dependent) diabetes mellitus is not altered by short-term deterioration in glycaemic control or level of postprandial insulin replacement.
Academic Article Retinol-binding protein 4, insulin resistance, and type 2 diabetes.
Academic Article A significant role for histocompatibility in human islet transplantation.
Academic Article Variation in the perilipin gene (PLIN) affects glucose and lipid metabolism in non-Hispanic white women with and without polycystic ovary syndrome.
Academic Article Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic ß cell death and diabetes.
Academic Article Weight loss therapy improves pancreatic endocrine function in obese older adults.
Academic Article Glyburide enhances the responsiveness of the beta-cell to glucose but does not correct the abnormal patterns of insulin secretion in noninsulin-dependent diabetes mellitus.
Academic Article TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action.
Academic Article Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes.
Academic Article Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis.
Academic Article Ingestion of a mixed meal does not affect the metabolic clearance rate of biosynthetic human C-peptide.
Academic Article Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus.
Academic Article Moderate effect of duodenal-jejunal bypass surgery on glucose homeostasis in patients with type 2 diabetes.
Academic Article Reevaluation of urine C-peptide as measure of insulin secretion.
Academic Article Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus.
Academic Article Mutant insulin syndrome: identification of two families with [LeuA3]insulin and determination of its biological activity.
Academic Article Effect of glyburide on beta cell responsiveness to glucose in non-insulin-dependent diabetes mellitus.
Academic Article The metabolic effects of biosynthetic human proinsulin in individuals with type I diabetes.
Academic Article Defects in insulin secretion and action in women with a history of gestational diabetes.
Academic Article A new method for comparing portal and peripheral venous insulin delivery in humans: tolbutamide versus insulin infusion.
Academic Article Variable deterioration in cortical function during insulin-induced hypoglycemia.
Academic Article Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat.
Academic Article Alterations in the patterns of insulin secretion before and after diagnosis of IDDM.
Academic Article Measurement of proinsulin and intermediates. Validation of immunoassay methods by high-performance liquid chromatography.
Academic Article Insulin secretion in insulin-resistant women with a history of gestational diabetes.
Academic Article Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency.
Academic Article Insulin secretory profiles and C-peptide clearance kinetics at 6 months and 2 years after kidney-pancreas transplantation.
Academic Article The effect of biosynthetic human proinsulin on the hepatic response to glucagon in insulin-deficient diabetes.
Academic Article Glucose counterregulation in patients after pancreatectomy. Comparison with other clinical forms of diabetes.
Academic Article Relation of counterregulatory responses to hypoglycemia in type I diabetics.
Academic Article Lilly Lecture 1994. The beta-cell in diabetes: from molecular genetics to clinical research.
Academic Article Alterations in immunoreactive proinsulin and insulin clearance induced by weight loss in NIDDM.
Academic Article Alterations in pulsatile insulin secretion in the Zucker diabetic fatty rat.
Academic Article Glucagon does not increase plasma free fatty acid and glycerol concentrations in patients with noninsulin-dependent diabetes mellitus.
Academic Article Diagnosis of acromegaly in a patient with type 1 diabetes mellitus.
Academic Article Portal vein thrombosis complicating islet transplantation in a recipient with the Factor V Leiden mutation.
Academic Article Abnormal insulin secretion, not insulin resistance, is the genetic or primary defect of MODY in the RW pedigree.
Academic Article International trial of the Edmonton protocol for islet transplantation.
Academic Article Ginseng and ginsenoside Re do not improve ß-cell function or insulin sensitivity in overweight and obese subjects with impaired glucose tolerance or diabetes.
Academic Article Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type I diabetic patients.
Academic Article C-peptide as a measure of the secretion and hepatic extraction of insulin. Pitfalls and limitations.
Academic Article Altered insulin secretory responses to glucose in subjects with a mutation in the MODY1 gene on chromosome 20.
Academic Article Relative effects of calorie restriction and weight loss in noninsulin-dependent diabetes mellitus.
Academic Article Lack of control by glucose of ultradian insulin secretory oscillations in impaired glucose tolerance and in non-insulin-dependent diabetes mellitus.
Academic Article Xenin-25 delays gastric emptying and reduces postprandial glucose levels in humans with and without type 2 diabetes.
Academic Article ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.
Academic Article ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.

Search Criteria
  • Diabetes Mellitus Adult Onset