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One or more keywords matched the following properties of Schmidt-Ott, Urs C.
keywords Pattern Formation
overview The Schmidt-Ott lab uses experimental and genomic approaches to study the evolution of embryogenesis in flies, including midges and mosquitoes (Diptera). We seek to understand how and why, in embryos, morphogenesis, pattern formation, axis specification, gene regulation, and gene function change over time. For example, we discovered that the embryos of different fly species use structurally unrelated genes to establish embryo polarity and seek to understand why these essential developmental genes are frequently replaced in evolution and how they acquire this function. In another project, we discovered that the dynamics of a morphogen gradient required for tissue differentiation differs between species. We seek to understand how morphgogen gradient dynamics evolve and alter embryogenesis, including tissue specification and morphogenesis. In general, we welcome students and scholars who are interested in understanding how plasticity and robustness of embryogenesis shape the genetic basis of embryos over time.
One or more keywords matched the following items that are connected to Schmidt-Ott, Urs C.
Item TypeName
Concept Body Patterning
Academic Article Different ways to make a head.
Academic Article The anterior determinant bicoid of Drosophila is a derived Hox class 3 gene.
Academic Article Evo-devo aspects of classical and molecular data in a historical perspective.
Academic Article Evidence for a composite anterior determinant in the hover fly Episyrphus balteatus (Syrphidae), a cyclorrhaphan fly with an anterodorsal serosa anlage.
Academic Article Maternal activation of gap genes in the hover fly Episyrphus.
Academic Article Insect serosa: a head line in comparative developmental genetics.
Academic Article Hox3/zen and the evolution of extraembryonic epithelia in insects.
Academic Article Number, identity, and sequence of the Drosophila head segments as revealed by neural elements and their deletion patterns in mutants.
Academic Article Quantitative system drift compensates for altered maternal inputs to the gap gene network of the scuttle fly Megaselia abdita.
Academic Article Embryo development. A cysteine-clamp gene drives embryo polarity in the midge Chironomus.
Academic Article Emerging developmental genetic model systems in holometabolous insects.
Academic Article Functional evolution of a morphogenetic gradient.
Academic Article Ancient mechanisms for the evolution of the bicoid homeodomain's function in fly development.
Grant Genetic variation and function of body axis determinants in midges and other flies
Academic Article Embryo polarity in moth flies and mosquitoes relies on distinct old genes with localized transcript isoforms.
Academic Article Evolution and loss of ?-catenin and TCF-dependent axis specification in insects.
Search Criteria
  • Pattern
  • Formation