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Weichselbaum, Ralph R.
One or more keywords matched the following items that are connected to Weichselbaum, Ralph R.
Item TypeName
Concept Mice, Inbred C3H
Concept Mice, Inbred Strains
Concept Mice, Transgenic
Concept Mice, Inbred BALB C
Concept Mice, Inbred C57BL
Concept Mice, Nude
Concept Mice, Knockout
Concept Mice
Concept Mice, Mutant Strains
Concept Mice, SCID
Concept Mice, Inbred NOD
Academic Article Cross-talk between ceramide and PKC activity in the control of apoptosis in WEHI-231.
Academic Article Footprinting of individual tumors and their variants by constitutive cytokine expression patterns.
Academic Article The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.
Academic Article Tumor necrosis factor alpha (TNF-alpha) gene therapy targeted by ionizing radiation selectively damages tumor vasculature.
Academic Article DNA double-strand break rejoining rates, inherent radiation sensitivity and human tumour response to radiotherapy.
Academic Article Differential retention of tumor- and differentiation-suppressor functions in cells derived from a human squamous cell carcinoma.
Academic Article Growth factors alter the therapeutic ratio in radiotherapy.
Academic Article Radiation can inhibit tumor growth indirectly while depleting circulating leukocytes.
Academic Article Loss of ceramide production confers resistance to radiation-induced apoptosis.
Academic Article Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: a new paradigm for destruction of therapeutically intractable tumors.
Academic Article Modulation of apoptotic response of a radiation-resistant human carcinoma by Pseudomonas exotoxin-chimeric protein.
Academic Article Increased injection number enhances adenoviral genetic radiotherapy.
Academic Article Functional interaction between DNA-PK and c-Abl in response to DNA damage.
Academic Article Virally directed cytosine deaminase/5-fluorocytosine gene therapy enhances radiation response in human cancer xenografts.
Academic Article Decreasing the apoptotic threshold of tumor cells through protein kinase C inhibition and sphingomyelinase activation increases tumor killing by ionizing radiation.
Academic Article Combined effects of angiostatin and ionizing radiation in antitumour therapy.
Academic Article Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin.
Academic Article Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors.
Academic Article p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.
Academic Article Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation.
Academic Article Functional role for the c-Abl tyrosine kinase in meiosis I.
Academic Article NM-3, an isocoumarin, increases the antitumor effects of radiotherapy without toxicity.
Academic Article Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft.
Academic Article Treatment of head and neck and esophageal xenografts employing Alimta and concurrent ionizing radiation.
Academic Article Enhanced eradication of local and distant tumors by genetically produced interleukin-12 and radiation.
Academic Article In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo.
Academic Article Anti-angiogenic cues from vascular basement membrane collagen.
Academic Article Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage.
Academic Article Down-regulation of ceramide production abrogates ionizing radiation-induced cytochrome c release and apoptosis.
Academic Article TNFerade Biologic: preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene.
Academic Article Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma.
Academic Article Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species.
Academic Article Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts.
Academic Article The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin.
Academic Article Selective gene expression using a DF3/MUC1 promoter in a human esophageal adenocarcinoma model.
Academic Article The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma.
Academic Article Inhibition of glioma cell growth and tumorigenic potential by CCN3 (NOV).
Academic Article Inhibition of spontaneous metastases formation by amifostine.
Academic Article Angiostatin potentiates cyclophosphamide treatment of metastatic disease.
Academic Article Antimetastatic effectiveness of amifostine therapy following surgical removal of Sa-NH tumors in mice.
Academic Article Transcriptional control of viral gene therapy by cisplatin.
Academic Article Histone H2AX phosphorylation as a predictor of radiosensitivity and target for radiotherapy.
Academic Article Prolonged treatment with angiostatin reduces metastatic burden during radiation therapy.
Academic Article STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.
Academic Article Radiation therapy: activation for gene transcription and the development of genetic radiotherapy-therapeutic strategies in oncology.
Academic Article Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance.
Academic Article Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma.
Academic Article Dual induction of the Epo-Egr-TNF-alpha- plasmid in hypoxic human colon adenocarcinoma produces tumor growth delay.
Academic Article Radiation's outer limits.
Academic Article Forphenicinol enhances the antitumor effects of cyclophosphamide in a model of squamous cell carcinoma.
Academic Article Bugging the intestinal response to radiation.
Academic Article Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1.
Academic Article Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses.
Academic Article Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy.
Academic Article An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer.
Academic Article MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer.
Academic Article Oral PEG 15-20 protects the intestine against radiation: role of lipid rafts.
Academic Article Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma.
Academic Article Characterization of response to radiation mediated gene therapy by means of multimodality imaging.
Academic Article How does antiangiogenic therapy affect brain tumor response to radiation?
Academic Article Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment.
Academic Article Simvastatin attenuates radiation-induced murine lung injury and dysregulated lung gene expression.
Academic Article Induced sensitization of tumor stroma leads to eradication of established cancer by T cells.
Academic Article STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect.
Academic Article Poly(ADP-ribose) polymerase inhibitor induces accelerated senescence in irradiated breast cancer cells and tumors.
Academic Article Where it's at really matters: in situ in vivo vascular endothelial growth factor spatially correlates with electron paramagnetic resonance pO2 images in tumors of living mice.
Academic Article Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity.
Academic Article The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity.
Academic Article Increased oncolytic efficacy for high-grade gliomas by optimal integration of ionizing radiation into the replicative cycle of HSV-1.
Academic Article Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation.
Academic Article Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy.
Academic Article Cell biological effects of total body irradiation on growth and differentiation of acute myelogenous leukemia cells compared to normal bone marrow.
Academic Article Sensitivities of NIH/3T3-derived clonal cell lines to ionizing radiation: significance for gene transfer studies.
Academic Article Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes.
Academic Article Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression.
Academic Article SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine.
Academic Article STAT1 pathway mediates amplification of metastatic potential and resistance to therapy.
Academic Article Blockade of tumor necrosis factor alpha signaling in tumor-associated macrophages as a radiosensitizing strategy.
Academic Article Ad.Egr-TNF and local ionizing radiation suppress metastases by interferon-beta-dependent activation of antigen-specific CD8+ T cells.
Academic Article Spleen cells from young but not old immunized mice eradicate large established cancers.
Academic Article Efficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context.
Academic Article Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs.
Academic Article Effects of 17 beta-estradiol on radiation transformation in vitro; inhibition of effects by protease inhibitors.
Academic Article Importance of repair of potentially lethal damage in assays of cytotoxic agents.
Academic Article Modification by dexamethasone of radiation response of in vitro cultured cells.
Academic Article Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents.
Academic Article Clonal interactions in a human squamous cell carcinoma.
Academic Article The raf oncogene is associated with a radiation-resistant human laryngeal cancer.
Academic Article Gene therapy targeted by radiation preferentially radiosensitizes tumor cells.
Academic Article Local gene delivery of tumor necrosis factor alpha can impact primary tumor growth and metastases through a host-mediated response.
Academic Article Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells.
Academic Article Resveratrol is an effective inducer of CArG-driven TNF-alpha gene therapy.
Academic Article Spatial and temporal control of gene therapy using ionizing radiation.
Academic Article Extraction and assembly of tissue-derived gels for cell culture and tissue engineering.
Academic Article Growth and magnetic resonance characteristics of human squamous cell carcinoma xenografts implanted with cells suspended in Matrigel.
Academic Article Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer.
Academic Article Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine.
Academic Article Tumor endothelial inflammation predicts clinical outcome in diverse human cancers.
Academic Article The effect of the alpha-emitting radionuclide lead-212 on human ovarian carcinoma: a potential new form of therapy.
Academic Article Chromosome 13 restriction fragment length polymorphisms.
Academic Article Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and -independent mechanisms.
Academic Article Blockage of the early events of mitogenic signaling by interferon-gamma in macrophages in response to colony-stimulating factor-1.
Academic Article Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase.
Academic Article Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer.
Academic Article Ionizing radiation improves survival in mice bearing intracranial high-grade gliomas injected with genetically modified herpes simplex virus.
Academic Article Antitumor interaction of short-course endostatin and ionizing radiation.
Academic Article Tumor production of angiostatin is enhanced after exposure to TNF-alpha.
Academic Article A downside to apoptosis in cancer therapy?
Academic Article p50 (NF-?B1) is an effector protein in the cytotoxic response to DNA methylation damage.
Academic Article MicroRNA expression characterizes oligometastasis(es).
Academic Article Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer.
Academic Article Genetic radiotherapy overcomes tumor resistance to cytotoxic agents.
Academic Article Influence of the pineal on wound healing.
Academic Article Release of spleen focus-forming virus (SFFV) from differentiation inducible promyelocytic leukemia cell lines transformed in vitro by Friend leukemia virus.
Academic Article Effects of dexamethasone and cortisone with x-ray irradiation on transformation of C3H 10T 1/2 cells.
Academic Article DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-?B p50 and a single nucleotide in the ?B-site.
Academic Article A manganese superoxide dismutase (SOD2)-mediated adaptive response.
Academic Article Radiation-induced equilibrium is a balance between tumor cell proliferation and T cell-mediated killing.
Academic Article A survivin-associated adaptive response in radiation therapy.
Academic Article Role of migratory inhibition factor in age-related susceptibility to radiation lung injury via NF-E2-related factor-2 and antioxidant regulation.
Academic Article Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor.
Academic Article RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation.
Academic Article Targeting the tumor microenvironment with interferon-ß bridges innate and adaptive immune responses.
Academic Article Loss of Nfkb1 leads to early onset aging.
Academic Article STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.
Academic Article EPR oxygen images predict tumor control by a 50% tumor control radiation dose.
Academic Article Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma.
Academic Article Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure.
Academic Article Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice.
Academic Article The RAD51-stimulatory compound RS-1 can exploit the RAD51 overexpression that exists in cancer cells and tumors.
Academic Article Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide.
Academic Article 14q32-encoded microRNAs mediate an oligometastatic phenotype.
Academic Article Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome.
Academic Article MUC1-C activates the TAK1 inflammatory pathway in colon cancer.
Academic Article Protection from Radiation-Induced Pulmonary Fibrosis by Peripheral Targeting of Cannabinoid Receptor-1.
Academic Article Role of GADD45a in murine models of radiation- and bleomycin-induced lung injury.
Academic Article Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
Academic Article Tumor-associated fibroblasts predominantly come from local and not circulating precursors.
Academic Article Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy.
Academic Article Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs.
Academic Article Repurposing cephalosporin antibiotics as pro-senescent radiosensitizers.
Academic Article Chlorin-Based Nanoscale Metal-Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy.
Academic Article Image-Guided Radiotherapy Targets Macromolecules through Altering the Tumor Microenvironment.
Academic Article Very low doses of ionizing radiation and redox associated modifiers affect survivin-associated changes in radiation sensitivity.
Academic Article Basal Tumor Cell Isolation and Patient-Derived Xenograft Engraftment Identify High-Risk Clinical Bladder Cancers.
Academic Article Combination of radiotherapy and vaccination overcomes checkpoint blockade resistance.
Academic Article Photodynamic Therapy Mediated by Nontoxic Core-Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer.
Academic Article Transfer of Allogeneic CD4+ T Cells Rescues CD8+ T Cells in Anti-PD-L1-Resistant Tumors Leading to Tumor Eradication.
Academic Article Tumour ischaemia by interferon-? resembles physiological blood vessel regression.
Academic Article Type 3 innate lymphoid cell-derived lymphotoxin prevents microbiota-dependent inflammation.
Academic Article In Vivo Delivery and Therapeutic Effects of a MicroRNA on Colorectal Liver Metastases.
Academic Article Human Organoids Share Structural and Genetic Features with Primary Pancreatic Adenocarcinoma Tumors.
Academic Article Host STING-dependent MDSC mobilization drives extrinsic radiation resistance.
Academic Article STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability.
Academic Article Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein a Signaling.
Academic Article JAK2 Inhibitor SAR302503 Abrogates PD-L1 Expression and Targets Therapy-Resistant Non-small Cell Lung Cancers.
Academic Article HMG-CoA Reductase Inhibition Delays DNA Repair and Promotes Senescence After Tumor Irradiation.
Academic Article A Critical Role of the IL-1ß-IL-1R Signaling Pathway in Skin Inflammation and Psoriasis Pathogenesis.
Academic Article Oxygen-Guided Radiation Therapy.
Academic Article Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy.
Academic Article Non-canonical NF-?B Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy.
Academic Article DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs.
Academic Article Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells.
Academic Article Temozolomide Treatment Induces lncRNA MALAT1 in an NF-?B and p53 Codependent Manner in Glioblastoma.
Academic Article Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors.
Academic Article Low-dose X-ray radiotherapy-radiodynamic therapy via nanoscale metal-organic frameworks enhances checkpoint blockade immunotherapy.
Academic Article Systemic miRNA delivery by nontoxic nanoscale coordination polymers limits epithelial-to-mesenchymal transition and suppresses liver metastases of colorectal cancer.
Academic Article STING (or SRC) Like an ICB: Priming the Immune Response in Pancreatic Cancer.
Academic Article Tumor-reprogrammed resident T cells resist radiation to control tumors.
Academic Article Western Diet Promotes Intestinal Colonization by Collagenolytic Microbes and Promotes Tumor Formation After Colorectal Surgery.
Academic Article Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling.
Academic Article DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-?B and sensitize to alkylating chemotherapy.
Academic Article Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens.
Academic Article Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity.
Academic Article 4-Hydroxyacetophenone modulates the actomyosin cytoskeleton to reduce metastasis.
Academic Article Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells.
Academic Article p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability.
Academic Article RIG-I-Like Receptor LGP2 Is Required for Tumor Control by Radiotherapy.
Academic Article Small Animal IMRT Using 3D-Printed Compensators.
Academic Article Suppression of local type I interferon by gut microbiota-derived butyrate impairs antitumor effects of ionizing radiation.
Academic Article Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity.
Academic Article Lactobacillus rhamnosus GG induces cGAS/STING- dependent type I interferon and improves response to immune checkpoint blockade.
Academic Article The AIM2 and NLRP3 inflammasomes trigger IL-1-mediated antitumor effects during radiation.
Academic Article Sunitinib-Loaded Chondroitin Sulfate Hydrogels as a Novel Drug-Delivery Mechanism for the Treatment of Pancreatic Neuroendocrine Tumors.
Academic Article Reprogramming of Neutrophils as Non-canonical Antigen Presenting Cells by Radiotherapy-Radiodynamic Therapy to Facilitate Immune-Mediated Tumor Regression.
Academic Article All-trans retinoic acid overcomes solid tumor radioresistance by inducing inflammatory macrophages.
Academic Article Synergistic checkpoint-blockade and radiotherapy-radiodynamic therapy via an immunomodulatory nanoscale metal-organic framework.
Academic Article Enterococcus faecalis promotes a migratory and invasive phenotype in colon cancer cells.
Academic Article Tumor-Activatable Nanoparticles Target Low-Density Lipoprotein Receptor to Enhance Drug Delivery and Antitumor Efficacy.
Academic Article A Three-in-One Nanoscale Coordination Polymer for Potent Chemo-Immunotherapy.
Academic Article TLR3 agonist nanoscale coordination polymer synergizes with immune checkpoint blockade for immunotherapy of cancer.
Academic Article YTHDF2/m6 A/NF-?B axis controls anti-tumor immunity by regulating intratumoral Tregs.
Academic Article YTHDF2 inhibition potentiates radiotherapy antitumor efficacy.
Academic Article Nanoscale Metal-Organic Framework with an X-ray Triggerable Prodrug for Synergistic Radiotherapy and Chemotherapy.
Academic Article Accelerator-Based Production of Scandium Radioisotopes for Applications in Prostate Cancer: Toward Building a Pipeline for Rapid Development of Novel Theranostics.
Academic Article Western Diet-induced Transcriptional Changes in Anastomotic Tissue Is Associated With Early Local Recurrence in a Mouse Model of Colorectal Surgery.
Academic Article Nanoscale Covalent Organic Framework with Staggered Stacking of Phthalocyanines for Mitochondria-Targeted Photodynamic Therapy.
Academic Article Epitranscriptional regulation of TGF-ß pseudoreceptor BAMBI by m6A/YTHDF2 drives extrinsic radioresistance.
Academic Article Immunogenic Bifunctional Nanoparticle Suppresses Programmed Cell Death-Ligand 1 in Cancer and Dendritic Cells to Enhance Adaptive Immunity and Chemo-Immunotherapy.
Academic Article Radiotherapy Enhances Metastasis Through Immune Suppression by Inducing PD-L1 and MDSC in Distal Sites.
Academic Article Nanoparticles Synergize Ferroptosis and Cuproptosis to Potentiate Cancer Immunotherapy.
Academic Article Targeting the Dendritic Cell-Secreted Immunoregulatory Cytokine CCL22 Alleviates Radioresistance.
Academic Article Mitochondria-Targeted Multifunctional Nanoparticles Combine Cuproptosis and Programmed Cell Death-1 Downregulation for Cancer Immunotherapy.
Academic Article STING activation disrupts tumor vasculature to overcome the EPR limitation and increase drug deposition.
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