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Weichselbaum, Ralph R.

One or more keywords matched the following items that are connected to Weichselbaum, Ralph R.

Item Type	Name
Concept	Protein-Tyrosine Kinases
Concept	Protein Kinases
Concept	Thymidine Kinase
Concept	Phosphotransferases (Alcohol Group Acceptor)
Concept	Mitogen-Activated Protein Kinases
Concept	MAP Kinase Kinase 1
Concept	MAP Kinase Kinase 7
Concept	src-Family Kinases
Concept	DNA-Activated Protein Kinase
Concept	Receptor Protein-Tyrosine Kinases
Concept	MAP Kinase Kinase Kinases
Concept	eIF-2 Kinase
Concept	Mitogen-Activated Protein Kinase 10
Concept	MAP Kinase Kinase 4
Concept	Protein Kinase C-delta
Concept	Mitogen-Activated Protein Kinase 3
Concept	Ribosomal Protein S6 Kinases
Concept	Cyclin-Dependent Kinase Inhibitor p16
Concept	Mitogen-Activated Protein Kinase Kinases
Concept	Cyclin-Dependent Kinase Inhibitor p21
Concept	Protein Kinase C
Concept	Glycogen Synthase Kinase 3
Concept	TOR Serine-Threonine Kinases
Concept	MAP Kinase Kinase Kinase 1
Concept	CDC2 Protein Kinase
Concept	Cyclin-Dependent Kinases
Concept	Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
Concept	Mitogen-Activated Protein Kinase 1
Concept	Calcium-Calmodulin-Dependent Protein Kinases
Concept	Phosphatidylinositol 3-Kinases
Concept	MAP Kinase Signaling System
Concept	JNK Mitogen-Activated Protein Kinases
Concept	Extracellular Signal-Regulated MAP Kinases
Concept	Janus Kinase 2
Concept	Class II Phosphatidylinositol 3-Kinases
Concept	Ribosomal Protein S6 Kinases, 70-kDa
Concept	CDC2-CDC28 Kinases
Concept	Protein Kinase Inhibitors
Concept	p38 Mitogen-Activated Protein Kinases
Concept	Cyclin-Dependent Kinase 2
Academic Article	Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation.
Academic Article	Protein kinase C inhibition induces apoptosis and ceramide production through activation of a neutral sphingomyelinase.
Academic Article	Cross-talk between ceramide and PKC activity in the control of apoptosis in WEHI-231.
Academic Article	Radiation signaling mediated by Jun activation following dissociation from a cell type-specific repressor.
Academic Article	The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.
Academic Article	Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.
Academic Article	Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.
Academic Article	Down-regulation of cell cycle control genes by ionizing radiation.
Academic Article	Nuclear signaling induced by ionizing radiation involves colocalization of the activated p56/p53lyn tyrosine kinase with p34cdc2.
Academic Article	Involvement of reactive oxygen intermediates in the induction of c-jun gene transcription by ionizing radiation.
Academic Article	The isoquinoline sulfonamide H7 attenuates radiation-mediated protein kinase C activation and delays the onset of x-ray-induced G2 arrest.
Academic Article	Inhibition of protein kinases sensitizes human tumor cells to ionizing radiation.
Academic Article	Functional interaction between DNA-PK and c-Abl in response to DNA damage.
Academic Article	Inhibition of phosphatidylinositol 3-kinase by c-Abl in the genotoxic stress response.
Academic Article	Activation of protein kinase C delta by the c-Abl tyrosine kinase in response to ionizing radiation.
Academic Article	Decreasing the apoptotic threshold of tumor cells through protein kinase C inhibition and sphingomyelinase activation increases tumor killing by ionizing radiation.
Academic Article	Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase.
Academic Article	Determination of cell fate by c-Abl activation in the response to DNA damage.
Academic Article	p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.
Academic Article	Functional role for the c-Abl tyrosine kinase in meiosis I.
Academic Article	Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage.
Academic Article	Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90.
Academic Article	Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase.
Academic Article	Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage.
Academic Article	In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo.
Academic Article	Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage.
Academic Article	E2F proteins are posttranslationally modified concomitantly with a reduction in nuclear binding activity in cells infected with herpes simplex virus 1.
Academic Article	Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3.
Academic Article	cis-Diamminedichloroplatinum(II) induces c-jun expression in human myeloid leukemia cells: potential involvement of a protein kinase C-dependent signaling pathway.
Academic Article	Interaction of hematopoietic progenitor kinase 1 and c-Abl tyrosine kinase in response to genotoxic stress.
Academic Article	Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species.
Academic Article	cdc2 cyclin-dependent kinase binds and phosphorylates herpes simplex virus 1 U(L)42 DNA synthesis processivity factor.
Academic Article	Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts.
Academic Article	The role of cdc2 in the expression of herpes simplex virus genes.
Academic Article	Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes.
Academic Article	The novel isocoumarin 2-(8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl) propionic acid (NM-3) induces lethality of human carcinoma cells by generation of reactive oxygen species.
Academic Article	Ionizing radiation induces expression and binding activity of the nuclear factor kappa B.
Academic Article	Tumour-endothelium interactions in co-culture: coordinated changes of gene expression profiles and phenotypic properties of endothelial cells.
Academic Article	Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.
Academic Article	Lyn tyrosine kinase inhibits nuclear export of the p53 tumor suppressor.
Academic Article	Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation.
Academic Article	Posttranslational processing of infected cell proteins 0 and 4 of herpes simplex virus 1 is sequential and reflects the subcellular compartment in which the proteins localize.
Academic Article	Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance.
Academic Article	Radiation's outer limits.
Academic Article	Mechanisms of X-ray-mediated protooncogene c-jun expression in radiation-induced human sarcoma cell lines.
Academic Article	Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1.
Academic Article	Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses.
Academic Article	Tumor genotype determines susceptibility to oncolytic herpes simplex virus mutants: strategies for clinical application.
Academic Article	c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage.
Academic Article	Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity.
Academic Article	Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression.
Academic Article	Ionizing radiation stimulates a Grb2-mediated association of the stress-activated protein kinase with phosphatidylinositol 3-kinase.
Academic Article	Efficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context.
Academic Article	p56/p53lyn tyrosine kinase activation in mammalian cells treated with mitomycin C.
Academic Article	Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents.
Academic Article	Activation of Src-like p56/p53lyn tyrosine kinase by ionizing radiation.
Academic Article	Ionizing radiation induces rapid tyrosine phosphorylation of p34cdc2.
Academic Article	Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation.
Academic Article	Membrane-derived second messenger regulates x-ray-mediated tumor necrosis factor alpha gene induction.
Academic Article	Ionizing radiation activates transcription of the EGR1 gene via CArG elements.
Academic Article	Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and -independent mechanisms.
Academic Article	Blockage of the early events of mitogenic signaling by interferon-gamma in macrophages in response to colony-stimulating factor-1.
Academic Article	Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase.
Academic Article	Functional role for the c-Abl protein tyrosine kinase in the cellular response to genotoxic stress.
Academic Article	The role of intracellular calcium in the cellular response to ionizing radiation.
Academic Article	Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis.
Academic Article	The disappearance of cyclins A and B and the increase in activity of the G(2)/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the alpha22/U(S)1.5 and U(L)13 viral genes.
Academic Article	Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1.
Academic Article	Glioblastoma cells block radiation-induced programmed cell death of endothelial cells.
Academic Article	Attenuated herpes simplex virus 1 blocks arterial apoptosis and intimal hyperplasia induced by balloon angioplasty and reduced blood flow.
Academic Article	Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer.
Academic Article	Activation of the pp90rsk and mitogen-activated serine/threonine protein kinases by ionizing radiation.
Academic Article	Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury.
Academic Article	Modulating vascular intimal hyperplasia using HSV-1 mutant requires activated MEK.
Academic Article	DNA repair biomarkers XPF and phospho-MAPKAP kinase 2 correlate with clinical outcome in advanced head and neck cancer.
Academic Article	MUC1-C activates the TAK1 inflammatory pathway in colon cancer.
Academic Article	Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
Academic Article	Nonmuscle myosin light chain kinase activity modulates radiation-induced lung injury.
Academic Article	JAK2 Inhibitor SAR302503 Abrogates PD-L1 Expression and Targets Therapy-Resistant Non-small Cell Lung Cancers.
Academic Article	Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis.
Academic Article	CDK1 is up-regulated by temozolomide in an NF-?B dependent manner in glioblastoma.
Academic Article	CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer.

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