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Hayward, Simon

One or more keywords matched the following items that are connected to Hayward, Simon

Item Type	Name
Concept	Prostate-Specific Antigen
Concept	Prostate
Academic Article	Heterogeneity of human prostate carcinoma-associated fibroblasts implicates a role for subpopulations in myeloid cell recruitment.
Academic Article	Hyperglycemia and T Cell infiltration are associated with stromal and epithelial prostatic hyperplasia in the nonobese diabetic mouse.
Academic Article	Identification of SFRP1 as a candidate mediator of stromal-to-epithelial signaling in prostate cancer.
Academic Article	Evidence that the prostate-specific antigen (PSA)/Zn2+ axis may play a role in human prostate cancer cell invasion.
Academic Article	NF-?B and androgen receptor variant expression correlate with human BPH progression.
Academic Article	Steroid hormones stimulate human prostate cancer progression and metastasis.
Academic Article	Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells.
Academic Article	Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype.
Academic Article	Use of tissue recombination to predict phenotypes of transgenic mouse models of prostate carcinoma.
Academic Article	Functional remodeling of benign human prostatic tissues in vivo by spontaneously immortalized progenitor and intermediate cells.
Academic Article	Androgen hormone action in prostatic carcinogenesis: stromal androgen receptors mediate prostate cancer progression, malignant transformation and metastasis.
Academic Article	FOXA1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype.
Academic Article	Shared Inherited Genetics of Benign Prostatic Hyperplasia and Prostate Cancer.
Academic Article	Down-regulation of p57Kip2 induces prostate cancer in the mouse.
Academic Article	The role of transforming growth factor-beta-mediated tumor-stroma interactions in prostate cancer progression: an integrative approach.
Academic Article	ALCAM/CD166 is a TGF-ß-responsive marker and functional regulator of prostate cancer metastasis to bone.
Academic Article	PPAR?: a molecular link between systemic metabolic disease and benign prostate hyperplasia.
Academic Article	Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium.
Academic Article	Stromal androgen receptor in prostate development and cancer.
Academic Article	DGAT1 Inhibitor Suppresses Prostate Tumor Growth and Migration by Regulating Intracellular Lipids and Non-Centrosomal MTOC Protein GM130.
Academic Article	Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations.
Academic Article	Lipid droplet velocity is a microenvironmental sensor of aggressive tumors regulated by V-ATPase and PEDF.
Academic Article	Genome-wide analysis of AR binding and comparison with transcript expression in primary human fetal prostate fibroblasts and cancer associated fibroblasts.
Academic Article	Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation.
Academic Article	Androgen regulated genes in human prostate xenografts in mice: relation to BPH and prostate cancer.
Academic Article	NE-10 neuroendocrine cancer promotes the LNCaP xenograft growth in castrated mice.
Academic Article	Propagation of human prostate tissue from induced pluripotent stem cells.
Academic Article	An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line.
Academic Article	Reduction of pro-tumorigenic activity of human prostate cancer-associated fibroblasts using Dlk1 or SCUBE1.
Academic Article	A genetic variant near GATA3 implicated in inherited susceptibility and etiology of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS).
Academic Article	Androgen receptor differentially regulates the proliferation of prostatic epithelial cells in vitro and in vivo.
Academic Article	Quantitation of apoptotic activity following castration in human prostatic tissue in vivo.
Academic Article	Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity.
Academic Article	A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells.
Academic Article	NF-?B and androgen receptor variant 7 induce expression of SRD5A isoforms and confer 5ARI resistance.
Academic Article	Tumor-secreted Hsp90 subverts polycomb function to drive prostate tumor growth and invasion.
Academic Article	Surgical intervention for symptomatic benign prostatic hyperplasia is correlated with expression of the AP-1 transcription factor network.
Academic Article	Targeting the tumor stroma as a novel therapeutic approach for prostate cancer.
Academic Article	E2f binding-deficient Rb1 protein suppresses prostate tumor progression in vivo.
Academic Article	Nfib Regulates Transcriptional Networks That Control the Development of Prostatic Hyperplasia.
Academic Article	Cathepsin D acts as an essential mediator to promote malignancy of benign prostatic epithelium.
Academic Article	Disruption of Rb/E2F pathway results in increased cyclooxygenase-2 expression and activity in prostate epithelial cells.
Academic Article	Review of Prostate Anatomy and Embryology and the Etiology of Benign Prostatic Hyperplasia.
Academic Article	Tissue-specific consequences of cyclin D1 overexpression in prostate cancer progression.
Academic Article	Tyrosine kinase inhibitor therapy prescribed for non-urologic diseases can modify PSA titers in urology patients.
Academic Article	A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells.
Academic Article	Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.
Academic Article	Development of a three-dimensional culture model of prostatic epithelial cells and its use for the study of epithelial-mesenchymal transition and inhibition of PI3K pathway in prostate cancer.
Academic Article	Ephrin B Activate Src Family Kinases in Fibroblasts Inducing Stromal Remodeling in Prostate Cancer.
Academic Article	Transcriptional profiling of inductive mesenchyme to identify molecules involved in prostate development and disease.
Academic Article	Human prostate organoid generation and the identification of prostate development drivers using inductive rodent tissues.
Academic Article	Rescue and isolation of Rb-deficient prostate epithelium by tissue recombination.
Academic Article	Interaction of prostate carcinoma-associated fibroblasts with human epithelial cell lines in vivo.
Academic Article	Isolation and analysis of discreet human prostate cellular populations.
Academic Article	Transforming growth factor-beta promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells.
Academic Article	Loss of ephrin B2 receptor (EPHB2) sets lipid rheostat by regulating proteins DGAT1 and ATGL inducing lipid droplet storage in prostate cancer cells.
Academic Article	Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis.
Academic Article	Development and characterization of efficient xenograft models for benign and malignant human prostate tissue.
Academic Article	Fibroblast heterogeneity in prostate carcinogenesis.
Academic Article	Role of the stromal microenvironment in carcinogenesis of the prostate.
Academic Article	PEDF regulates plasticity of a novel lipid-MTOC axis in prostate cancer-associated fibroblasts.
Academic Article	The role of the androgen receptor in prostate development and benign prostatic hyperplasia: A review.
Academic Article	Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia.
Academic Article	Role for stromal heterogeneity in prostate tumorigenesis.
Academic Article	The stress response mediator ATF3 represses androgen signaling by binding the androgen receptor.
Academic Article	Stromal reactivity differentially drives tumour cell evolution and prostate cancer progression.
Academic Article	Androgen-dependent prostate epithelial cell selection by targeting ARR(2)PBneo to the LPB-Tag model of prostate cancer.
Academic Article	Urothelial transdifferentiation to prostate epithelia is mediated by paracrine TGF-beta signaling.

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