| Item Type | Name |
|
Concept
|
Mitochondria, Heart
|
|
Concept
|
Mitochondria
|
|
Concept
|
Mitochondria, Muscle
|
|
Academic Article
|
Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation.
|
|
Academic Article
|
An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
|
|
Academic Article
|
Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells.
|
|
Academic Article
|
O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide.
|
|
Academic Article
|
Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction.
|
|
Academic Article
|
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.
|
|
Academic Article
|
Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure.
|
|
Academic Article
|
Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer.
|
|
Academic Article
|
Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.
|
|
Academic Article
|
Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target.
|
|
Academic Article
|
Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
|
|
Academic Article
|
The mitochondrion as a Swiss army knife: implications for cardiovascular disease.
|
|
Academic Article
|
Diversity in mitochondrial function explains differences in vascular oxygen sensing.
|
|
Academic Article
|
O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor.
|
|
Academic Article
|
A central role for oxygen-sensitive K+ channels and mitochondria in the specialized oxygen-sensing system.
|
|
Academic Article
|
Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer.
|
|
Academic Article
|
A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension.
|
|
Academic Article
|
Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus.
|
|
Academic Article
|
Mitochondrial dynamics in cardiovascular disease: fission and fusion foretell form and function.
|
|
Academic Article
|
SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress.
|
|
Academic Article
|
Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension.
|
|
Academic Article
|
Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibition of Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: Therapeutic Implications.
|
|
Academic Article
|
Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
|
|
Academic Article
|
Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertension.
|
|
Academic Article
|
The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease.
|
|
Academic Article
|
Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus.
|
|
Academic Article
|
Gone fission: an asymptomatic STAT2 mutation elongates mitochondria and causes human disease following viral infection.
|
|
Academic Article
|
Mitochondrial dynamics in pulmonary arterial hypertension.
|
|
Academic Article
|
A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus.
|
|
Academic Article
|
Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes.
|
|
Academic Article
|
Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen-Sensing, Metabolism, and Dynamics.
|
|
Academic Article
|
Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
|
|
Academic Article
|
Excess Protein O-GlcNAcylation Links Metabolic Derangements to Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
|
|
Academic Article
|
The molecular mechanisms of oxygen-sensing in human ductus arteriosus smooth muscle cells: A comprehensive transcriptome profile reveals a central role for mitochondria.
|
|
Academic Article
|
Mitochondrial iron-sulfur clusters: Structure, function, and an emerging role in vascular biology.
|
|
Academic Article
|
Mitochondria in human neutrophils mediate killing of Staphylococcus aureus.
|
|
Academic Article
|
Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance.
|
|
Grant
|
Impaired mitochondrial fusion in pulmonary arterial hypertension
|
|
Grant
|
The Role of DRP-1 and Mitochondrial Fission in Pulmonary Arterial Hypertension
|
|
Academic Article
|
Dynamin-related protein 1 is a critical regulator of mitochondrial calcium homeostasis during myocardial ischemia/reperfusion injury.
|