| Item Type | Name |
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Concept
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Calcium Channels
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Concept
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Calcium Channel Blockers
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Concept
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Calcium Channels, L-Type
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Concept
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Potassium Channels, Voltage-Gated
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Academic Article
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Oxygen-induced constriction of rabbit ductus arteriosus occurs via inhibition of a 4-aminopyridine-, voltage-sensitive potassium channel.
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Academic Article
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Activation of the cGMP-dependent protein kinase mimics the stimulatory effect of nitric oxide and cGMP on calcium-gated potassium channels.
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Academic Article
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Ion channels in the pulmonary vasculature.
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Academic Article
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Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes.
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Academic Article
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A maturational shift in pulmonary K+ channels, from Ca2+ sensitive to voltage dependent.
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Academic Article
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Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv1.5.
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Academic Article
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Dexfenfluramine elevates systemic blood pressure by inhibiting potassium currents in vascular smooth muscle cells.
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Academic Article
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Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels.
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Academic Article
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Voltage-gated potassium channels in human ductus arteriosus.
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Academic Article
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Primary pulmonary hypertension: a vascular biology and translational research "Work in progress".
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Academic Article
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Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models.
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Academic Article
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In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats.
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Academic Article
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An evidence-based approach to the management of pulmonary arterial hypertension.
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Academic Article
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The role of k+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension.
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Academic Article
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Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension.
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Academic Article
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The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted.
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Academic Article
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O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide.
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Academic Article
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Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.
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Academic Article
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Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus.
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Academic Article
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Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease.
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Academic Article
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Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction.
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Academic Article
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Developmental absence of the O2 sensitivity of L-type calcium channels in preterm ductus arteriosus smooth muscle cells impairs O2 constriction contributing to patent ductus arteriosus.
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Academic Article
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Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.
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Academic Article
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The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.
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Academic Article
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A KCNE1 missense variant (V47I) causing exercise-induced long QT syndrome (Romano Ward).
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Academic Article
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Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells.
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Academic Article
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Comparative effects of nisoldipine, nifedipine and bepridil on experimental pulmonary hypertension.
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Academic Article
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The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels.
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Academic Article
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O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor.
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Academic Article
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Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction.
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Academic Article
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MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype.
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Academic Article
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A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus.
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Grant
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O2 sensing in the human and rabbit ductus arteriosus.
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