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Gajewski, Thomas

One or more keywords matched the following items that are connected to Gajewski, Thomas

Item Type	Name
Concept	Protein-Tyrosine Kinases
Concept	Protein Kinases
Concept	Mitogen-Activated Protein Kinases
Concept	src-Family Kinases
Concept	MAP Kinase Kinase Kinases
Concept	Diacylglycerol Kinase
Concept	MAP Kinase Kinase 4
Concept	Protein Kinase C-delta
Concept	Mitogen-Activated Protein Kinase 3
Concept	Cyclin-Dependent Kinase Inhibitor p16
Concept	Protein Kinase C
Concept	Glycogen Synthase Kinase 3
Concept	TOR Serine-Threonine Kinases
Concept	Mitogen-Activated Protein Kinase 1
Concept	Calcium-Calmodulin-Dependent Protein Kinases
Concept	MAP Kinase Signaling System
Concept	JNK Mitogen-Activated Protein Kinases
Concept	Extracellular Signal-Regulated MAP Kinases
Concept	I-kappa B Kinase
Concept	Ribosomal Protein S6 Kinases, 70-kDa
Concept	ZAP-70 Protein-Tyrosine Kinase
Concept	Protein Kinase Inhibitors
Concept	p21-Activated Kinases
Academic Article	Apoptosis meets signal transduction: elimination of a BAD influence.
Academic Article	Blocked Ras activation in anergic CD4+ T cells.
Academic Article	Antigen-specific blockade of T cells in vivo using dimeric MHC peptide.
Academic Article	CD28 is not required for c-Jun N-terminal kinase activation in T cells.
Academic Article	Semiquantitative analysis of dynamic contrast enhanced MRI in cancer patients: Variability and changes in tumor tissue over time.
Academic Article	Differential Ras signaling via the antigen receptor and IL-2 receptor in primary T lymphocytes.
Academic Article	Actin cytoskeleton regulates calcium dynamics and NFAT nuclear duration.
Academic Article	Cutting edge: cytotoxic granule polarization and cytolysis can occur without central supramolecular activation cluster formation in CD8+ effector T cells.
Academic Article	Phase II study of the Flk-1 tyrosine kinase inhibitor SU5416 in advanced melanoma.
Academic Article	Protein kinase Ctheta focusing at the cSMAC is a consequence rather than cause of TCR signaling and is dependent on the MEK/ERK pathway.
Academic Article	T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-alpha.
Academic Article	Evidence implicating the Ras pathway in multiple CD28 costimulatory functions in CD4+ T cells.
Academic Article	Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells.
Academic Article	Transcriptional regulator early growth response gene 2 (Egr2) is required for T cell anergy in vitro and in vivo.
Academic Article	Induction of the increased Fyn kinase activity in anergic T helper type 1 clones requires calcium and protein synthesis and is sensitive to cyclosporin A.
Academic Article	Differential requirement for protein tyrosine kinase Fyn in the functional activation of antigen-specific T lymphocyte clones through the TCR or Thy-1.
Academic Article	Anergic T-lymphocyte clones have altered inositol phosphate, calcium, and tyrosine kinase signaling pathways.
Academic Article	Farnesyltransferase inhibitors inhibit T-cell cytokine production at the posttranscriptional level.
Academic Article	Phase I studies of sirolimus alone or in combination with pharmacokinetic modulators in advanced cancer patients.
Academic Article	Phase II study of the Src kinase inhibitor saracatinib (AZD0530) in metastatic melanoma.
Academic Article	Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104).
Academic Article	Combination of vemurafenib and cobimetinib in patients with advanced BRAF(V600)-mutated melanoma: a phase 1b study.
Academic Article	Cutting Edge: Engineering Active IKKß in T Cells Drives Tumor Rejection.
Academic Article	Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition.
Academic Article	Impact of oncogenic pathways on evasion of antitumour immune responses.
Academic Article	A pharmacodynamic study of sirolimus and metformin in patients with advanced solid tumors.
Academic Article	Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion.
Academic Article	PAK4 as a cancer immune-evasion target.
Concept	Protein Kinase C-theta
Academic Article	PKCd Germline Variants and Genetic Deletion in Mice Augment Antitumor Immunity through Regulation of Myeloid Cells.
Grant	DGK in T Cell Regulation and Tolerance
Grant	Molecular Dissection of T Cell Anergy
Grant	EGR2 in T cell tolerance
Grant	Biochemical/Molecular Changes Upon Naive T Cell Priming

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