Item Type | Name |
Concept
|
C-Reactive Protein
|
Concept
|
DNA-Binding Proteins
|
Concept
|
Microtubule-Associated Proteins
|
Concept
|
Membrane Proteins
|
Concept
|
Microfilament Proteins
|
Concept
|
Nerve Tissue Proteins
|
Concept
|
Muscle Proteins
|
Concept
|
Protein Binding
|
Concept
|
Protein Conformation
|
Concept
|
Protein Processing, Post-Translational
|
Concept
|
Proto-Oncogene Proteins
|
Concept
|
Proteins
|
Concept
|
Repressor Proteins
|
Concept
|
Protein Biosynthesis
|
Concept
|
RGS Proteins
|
Concept
|
rho GTP-Binding Proteins
|
Concept
|
rhoB GTP-Binding Protein
|
Concept
|
rac1 GTP-Binding Protein
|
Concept
|
Mitogen-Activated Protein Kinases
|
Concept
|
Proto-Oncogene Proteins c-fos
|
Concept
|
Protein Structure, Tertiary
|
Concept
|
GTP-Binding Protein alpha Subunits, Gs
|
Concept
|
ras Proteins
|
Concept
|
Apoptosis Regulatory Proteins
|
Concept
|
GTP-Binding Protein alpha Subunits, Gi-Go
|
Concept
|
Bone Morphogenetic Protein Receptors, Type II
|
Concept
|
Mitochondrial Proteins
|
Concept
|
Cyclic GMP-Dependent Protein Kinases
|
Concept
|
Green Fluorescent Proteins
|
Concept
|
Sterol Regulatory Element Binding Protein 2
|
Concept
|
Cell Cycle Proteins
|
Concept
|
ras GTPase-Activating Proteins
|
Concept
|
rhoA GTP-Binding Protein
|
Concept
|
rac GTP-Binding Proteins
|
Concept
|
I-kappa B Proteins
|
Concept
|
Oncogene Protein v-akt
|
Concept
|
Early Growth Response Protein 1
|
Concept
|
Protein Kinase C
|
Concept
|
Recombinant Proteins
|
Concept
|
Period Circadian Proteins
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
Retinoblastoma Protein
|
Concept
|
Protein Prenylation
|
Concept
|
GTP-Binding Proteins
|
Concept
|
Mitogen-Activated Protein Kinase 1
|
Concept
|
cdc42 GTP-Binding Protein
|
Concept
|
Homeodomain Proteins
|
Concept
|
HSP90 Heat-Shock Proteins
|
Concept
|
Monomeric GTP-Binding Proteins
|
Concept
|
GTPase-Activating Proteins
|
Concept
|
JNK Mitogen-Activated Protein Kinases
|
Concept
|
Tumor Suppressor Proteins
|
Concept
|
Escherichia coli Proteins
|
Concept
|
LIM-Homeodomain Proteins
|
Concept
|
GTP-Binding Protein alpha Subunits, Gq-G11
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
Concept
|
Amyloid Precursor Protein Secretases
|
Concept
|
Carrier Proteins
|
Concept
|
Cytoskeletal Proteins
|
Concept
|
Nuclear Proteins
|
Concept
|
Recombinant Fusion Proteins
|
Concept
|
Tumor Suppressor Protein p53
|
Concept
|
Cyclic AMP-Dependent Protein Kinases
|
Concept
|
Protein Isoforms
|
Concept
|
Proto-Oncogene Proteins c-sis
|
Concept
|
Mitochondrial Membrane Transport Proteins
|
Concept
|
Vesicular Transport Proteins
|
Concept
|
Adaptor Proteins, Vesicular Transport
|
Concept
|
Protein Kinase Inhibitors
|
Concept
|
p38 Mitogen-Activated Protein Kinases
|
Concept
|
Proto-Oncogene Proteins c-akt
|
Concept
|
Smad Proteins
|
Academic Article
|
Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase.
|
Academic Article
|
Nongenomic mechanisms of endothelial nitric oxide synthase activation by the selective estrogen receptor modulator raloxifene.
|
Academic Article
|
Inhibition of Rho-kinase leads to rapid activation of phosphatidylinositol 3-kinase/protein kinase Akt and cardiovascular protection.
|
Academic Article
|
Rho-kinase mediates hyperglycemia-induced plasminogen activator inhibitor-1 expression in vascular endothelial cells.
|
Academic Article
|
Increased Rho kinase activity in a Taiwanese population with metabolic syndrome.
|
Academic Article
|
Increased vascular senescence and impaired endothelial progenitor cell function mediated by mutation of circadian gene Per2.
|
Academic Article
|
Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage.
|
Academic Article
|
Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection.
|
Academic Article
|
Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/- haploinsufficient mice.
|
Academic Article
|
Pleiotropic effects of statins. - Basic research and clinical perspectives -.
|
Academic Article
|
Smooth muscle Notch1 mediates neointimal formation after vascular injury.
|
Academic Article
|
Notch1 in bone marrow-derived cells mediates cardiac repair after myocardial infarction.
|
Academic Article
|
ROCK inhibition prevents fetal serum-induced alteration in structure and function of organ-cultured mesenteric artery.
|
Academic Article
|
Increased leukocyte Rho-associated coiled-coil containing protein kinase activity predicts the presence and severity of coronary vasospastic angina.
|
Academic Article
|
Increased Rho kinase activity in congestive heart failure.
|
Academic Article
|
Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion.
|
Academic Article
|
Statins inhibit Rho kinase activity in patients with atherosclerosis.
|
Academic Article
|
Rho-associated coiled-coil-forming kinases (ROCKs): potential targets for the treatment of atherosclerosis and vascular disease.
|
Academic Article
|
Roles of rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness.
|
Academic Article
|
Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen.
|
Academic Article
|
Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation.
|
Academic Article
|
Rho kinase: an important mediator of atherosclerosis and vascular disease.
|
Academic Article
|
Rho-associated kinase activity, endothelial function, and cardiovascular risk factors.
|
Academic Article
|
Induction of endothelial-leukocyte interaction by interferon-gamma requires coactivation of nuclear factor-kappaB.
|
Academic Article
|
Inhibition of vascular smooth muscle cell proliferation by sodium salicylate mediated by upregulation of p21(Waf1) and p27(Kip1).
|
Academic Article
|
Induction of angiogenesis by heat shock protein 90 mediated by protein kinase Akt and endothelial nitric oxide synthase.
|
Academic Article
|
Decreased vascular lesion formation in mice with inducible endothelial-specific expression of protein kinase Akt.
|
Academic Article
|
A novel pleiotropic effect of statins: prevention of cardiac hypertrophy by cholesterol-independent mechanisms.
|
Academic Article
|
Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells.
|
Academic Article
|
Endothelium-dependent effects of statins.
|
Academic Article
|
Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease.
|
Academic Article
|
Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors.
|
Academic Article
|
Activated Rho kinase mediates diabetes-induced elevation of vascular arginase activation and contributes to impaired corpora cavernosa relaxation: possible involvement of p38 MAPK activation.
|
Academic Article
|
A mouse model of diet-induced obesity and insulin resistance.
|
Academic Article
|
gamma-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice.
|
Academic Article
|
FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine kinase-1.
|
Academic Article
|
Rho-kinase: a potential link between hypercholesterolemia and abnormal vascular smooth muscle contraction.
|
Academic Article
|
Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.
|
Academic Article
|
Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription.
|
Academic Article
|
The G proteins of the G alpha i and G alpha q family couple the bradykinin receptor to the release of endothelium-derived relaxing factor.
|
Academic Article
|
Functional interaction of endothelial nitric oxide synthase with a voltage-dependent anion channel.
|
Academic Article
|
The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis.
|
Academic Article
|
Rac1 is a critical mediator of endothelium-derived neurotrophic activity.
|
Academic Article
|
Isoprenoids as mediators of the biological effects of statins.
|
Academic Article
|
Phosphatidylinositol 3-kinase/protein kinase Akt negatively regulates plasminogen activator inhibitor type 1 expression in vascular endothelial cells.
|
Academic Article
|
Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.
|
Academic Article
|
VEGF increases retinal vascular ICAM-1 expression in vivo.
|
Academic Article
|
Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR.
|
Academic Article
|
Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms.
|
Academic Article
|
3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1).
|
Academic Article
|
A functional role of I kappa B-epsilon in endothelial cell activation.
|
Academic Article
|
Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids.
|
Academic Article
|
Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids.
|
Academic Article
|
Cross-coupling between the oestrogen receptor and phosphoinositide 3-kinase.
|
Academic Article
|
Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2.
|
Academic Article
|
ROCKs as therapeutic targets in cardiovascular diseases.
|
Academic Article
|
Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis.
|
Academic Article
|
Nontranscriptional actions of the glucocorticoid receptor.
|
Academic Article
|
Rho GTPases, statins, and nitric oxide.
|
Academic Article
|
Activation of the phosphatidylinositol 3-kinase/protein kinase Akt pathway mediates nitric oxide-induced endothelial cell migration and angiogenesis.
|
Academic Article
|
Neuroprotection mediated by changes in the endothelial actin cytoskeleton.
|
Academic Article
|
Pleiotropic effects of statin therapy: molecular mechanisms and clinical results.
|
Academic Article
|
Physiological role of ROCKs in the cardiovascular system.
|
Academic Article
|
Inhibition of Rho-kinase attenuates endothelial-leukocyte interaction during ischemia-reperfusion injury.
|
Academic Article
|
Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis.
|
Academic Article
|
Regulation of myogenic terminal differentiation by the hairy-related transcription factor CHF2.
|
Academic Article
|
Inhibition of endothelial vascular cell adhesion molecule-1 expression by nitric oxide involves the induction and nuclear translocation of IkappaBalpha.
|
Academic Article
|
Requirement of Rac1 in the development of cardiac hypertrophy.
|
Academic Article
|
ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury.
|
Academic Article
|
Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids.
|
Academic Article
|
Modulation of bradykinin receptor ligand binding affinity and its coupled G-proteins by nitric oxide.
|
Academic Article
|
Simvastatin decreases IL-6 and IL-8 production in epithelial cells.
|
Academic Article
|
Statins and myocardial hypertrophy.
|
Academic Article
|
Absence of TRAM restricts Toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway.
|
Academic Article
|
Differential regulation of endothelial cell adhesion molecule expression by nitric oxide donors and antioxidants.
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Academic Article
|
Novel aspects of the roles of Rac1 GTPase in the cardiovascular system.
|
Academic Article
|
RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis.
|
Academic Article
|
Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase.
|
Academic Article
|
Regulation of endothelial nitric oxide synthase and postnatal angiogenesis by Rac1.
|
Academic Article
|
Regulation of G-protein alpha i2 subunit expression by oxidized low-density lipoprotein.
|
Academic Article
|
FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2.
|
Academic Article
|
Rapid nongenomic actions of thyroid hormone.
|
Academic Article
|
NADPH oxidase-derived superoxide anion mediates angiotensin II-induced cardiac hypertrophy.
|
Academic Article
|
Targeting eNOS and beyond: emerging heterogeneity of the role of endothelial Rho proteins in stroke protection.
|
Academic Article
|
Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy.
|
Academic Article
|
Fine-tuning the angiogenic response to vascular endothelial growth factor.
|
Academic Article
|
Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids.
|
Academic Article
|
Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase.
|
Academic Article
|
MnTBAP stimulates angiogenic functions in endothelial cells through mitofusin-1.
|
Academic Article
|
Critical role of endothelial Notch1 signaling in postnatal angiogenesis.
|
Academic Article
|
Peripheral plasma vitamin D and non-HDL cholesterol reflect the severity of cerebral cavernous malformation disease.
|
Academic Article
|
Elevated homocysteine and C-reactive protein levels independently predict worsening prognosis after stroke in Chinese patients.
|
Academic Article
|
Genetically elevated C-reactive protein and ischemic vascular disease.
|
Academic Article
|
Unique fractal evaluation and therapeutic implications of mitochondrial morphology in malignant mesothelioma.
|
Academic Article
|
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.
|
Academic Article
|
MnTBAP increases BMPR-II expression in endothelial cells and attenuates vascular inflammation.
|
Academic Article
|
RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations.
|
Academic Article
|
Activation of guanine nucleotide-binding proteins and induction of endothelial tissue-type plasminogen activator gene transcription by alcohol.
|
Academic Article
|
Targeting Rho in cardiovascular disease.
|
Academic Article
|
Specific receptor-guanine nucleotide binding protein interaction mediates the release of endothelium-derived relaxing factor.
|
Academic Article
|
[Regulation of endothelial NO production by Rho GTPase].
|
Academic Article
|
Tumor necrosis factor-alpha downregulates endothelial nitric oxide synthase mRNA stability via translation elongation factor 1-alpha 1.
|
Academic Article
|
Estrogens and glucocorticoids inhibit endothelial vascular cell adhesion molecule-1 expression by different transcriptional mechanisms.
|
Academic Article
|
Simvastatin reverses cardiac hypertrophy caused by disruption of the bradykinin 2 receptor.
|
Academic Article
|
ROCK as a therapeutic target for ischemic stroke.
|
Academic Article
|
Transcription factor CHF1/Hey2 suppresses cardiac hypertrophy through an inhibitory interaction with GATA4.
|
Academic Article
|
Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial.
|
Academic Article
|
Dynamic regulation of endothelial NOS mediated by competitive interaction with alpha-actinin-4 and calmodulin.
|
Academic Article
|
Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.
|
Academic Article
|
A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease.
|
Academic Article
|
Targeting Rho-associated coiled-coil forming protein kinase (ROCK) in cardiovascular fibrosis and stiffening.
|
Academic Article
|
Serine-threonine kinase ROCK2 regulates germinal center B cell positioning and cholesterol biosynthesis.
|
Academic Article
|
Regulator of G-Protein Signaling 5 Maintains Brain Endothelial Cell Function in Focal Cerebral Ischemia.
|
Academic Article
|
Increase in Blood-Brain Barrier (BBB) Permeability Is Regulated by MMP3 via the ERK Signaling Pathway.
|
Academic Article
|
Berberine suppresses MEK/ERK-dependent Egr-1 signaling pathway and inhibits vascular smooth muscle cell regrowth after in vitro mechanical injury.
|
Academic Article
|
Vascular Stiffening Mediated by Rho-Associated Coiled-Coil Containing Kinase Isoforms.
|
Concept
|
Forkhead Box Protein O1
|
Concept
|
Huntingtin Protein
|
Concept
|
KRIT1 Protein
|
Concept
|
Zonula Occludens-1 Protein
|
Concept
|
Tight Junction Proteins
|
Grant
|
GTP-BINDING PROTEINS AND MEDIATING EDRF RELEASE
|
Grant
|
Endothelial Akt in Vascular Injury
|
Grant
|
Lipoproteins Effect on G Protein Function
|
Grant
|
Activation of eNOS by Steroid Hormones
|
Grant
|
Role of PI3-Kinase in Estrogen-induced eNOS Activation
|