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One or more keywords matched the following properties of Chmura, Steven
overview Dr. Steven J. Chmura is an Associate Professor in the Department of Radiation and Cellular Oncology and Director of Clinical and Translational Research at The University of Chicago. Steven J. Chmura MD, PhD is the director of Clinical and Translational Research for Radiation Oncology at the University of Chicago for over a decade. He has been actively involved in both the clinical implementation of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT) and related translational and clinical research, as well as the integration of SRS and SBRT into other systemic therapies. His clinical interests include breast cancer, limited metastatic disease, immunotherapy, and technologic improvements in the delivery of radiotherapy. Dr. Chmura is a leader in the NCI cooperative groups. His work has led to the first international oligmetastatic trials through NRG Oncology examining the safety of treating lung and breast cancer patients as a Phase II/III trial examining potential improvements to progression-free survival and overall survival. Dr. Chmura's work in radio-immunology has also translated into multiple investigator-sponsored trials along with the now accruing NCI-sponsored (A091605) trial randomizing the role of SBRT combined with pembrolizumab in advanced Merkel cell carcinoma; such integration of ablative radiotherapy and immunotherapy along with advancing the search for biomarkers is currently Dr. Chmura's focus.
One or more keywords matched the following items that are connected to Chmura, Steven
Item TypeName
Concept Radiotherapy, Computer-Assisted
Concept Radiotherapy
Concept Radiotherapy Planning, Computer-Assisted
Concept Radiotherapy, Intensity-Modulated
Concept Radiotherapy, Conformal
Concept Radiotherapy Dosage
Concept Radiotherapy Setup Errors
Concept Radiotherapy, Image-Guided
Concept Radiotherapy, Adjuvant
Academic Article Radiogenetic therapy: on the interaction of viral therapy and ionizing radiation for improving local control of tumors.
Academic Article Is postmastectomy radiotherapy useful in elderly women with high-risk breast cancer?
Academic Article Long-term outcome of concurrent chemotherapy and reirradiation for recurrent and second primary head-and-neck squamous cell carcinoma.
Academic Article Evolving use of radiotherapy and radiosurgery in the treatment of pituitary adenomas.
Academic Article Intensity-modulated radiation therapy in advanced head and neck patients treated with intensive chemoradiotherapy: preliminary experience and future directions.
Academic Article Association between bone marrow dosimetric parameters and acute hematologic toxicity in anal cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy.
Academic Article Enhancing radiotherapy with genetically engineered viruses.
Academic Article Intensity-modulated radiotherapy in treatment of pancreatic and bile duct malignancies: toxicity and clinical outcome.
Academic Article An initial report of a radiation dose-escalation trial in patients with one to five sites of metastatic disease.
Academic Article Intensity-modulated radiation therapy (IMRT) in the treatment of anal cancer: toxicity and clinical outcome.
Academic Article Calculation and prediction of the effect of respiratory motion on whole breast radiation therapy dose distributions.
Academic Article A multi-institutional acute gastrointestinal toxicity analysis of anal cancer patients treated with concurrent intensity-modulated radiation therapy (IMRT) and chemotherapy.
Academic Article Optimization of the temporal pattern of radiation: an IMRT based study.
Academic Article Validation of temporal optimization effects for a single fraction of radiation in vitro.
Academic Article Characterization of a novel phantom for three-dimensional in vitro cell experiments.
Academic Article Concurrent chemotherapy and intensity-modulated radiation therapy for anal canal cancer patients: a multicenter experience.
Academic Article Stereotactic body radiotherapy for multisite extracranial oligometastases: final report of a dose escalation trial in patients with 1 to 5 sites of metastatic disease.
Academic Article Hypofractionated image-guided radiation therapy for patients with limited volume metastatic non-small cell lung cancer.
Academic Article Feasibility and acute toxicity of hypofractionated radiation in large-breasted patients.
Academic Article gamma-H2AX as a therapeutic target for improving the efficacy of radiation therapy.
Academic Article Intensity-modulated radiation therapy in the treatment of gastric cancer: early clinical outcome and dosimetric comparison with conventional techniques.
Academic Article Outcomes in black patients with early breast cancer treated with breast conservation therapy.
Academic Article The utility of FDG-PET for assessing outcomes in oligometastatic cancer patients treated with stereotactic body radiotherapy: a cohort study.
Academic Article Radiation oncology medical student clerkship: implementation and evaluation of a bi-institutional pilot curriculum.
Academic Article The role of surgery and ablative radiotherapy in oligometastatic breast cancer.
Academic Article Treatment of brain metastases.
Academic Article Assessment of interfractional variation of the breast surface following conventional patient positioning for whole-breast radiotherapy.
Academic Article An image-guided study of setup reproducibility of postmastectomy breast cancer patients treated with inverse-planned intensity modulated radiation therapy.
Academic Article Feasibility and toxicity of hypofractionated image guided radiation therapy for large volume limited metastatic disease.
Academic Article Effect of RTOG breast/chest wall guidelines on dose-volume histogram parameters.
Academic Article Stereotactic radiotherapy for pulmonary metastases.
Academic Article Hypofractionated radiotherapy does not increase acute toxicity in large-breasted women: results from a prospectively collected series.
Academic Article Surgery or ablative radiotherapy for breast cancer oligometastases.
Academic Article The evolving role of radiotherapy in treatment of oligometastatic NSCLC.
Academic Article Stereotactic body radiotherapy for oligometastatic breast cancer: a new standard of care, or a medical reversal in waiting?
Academic Article Clinical and molecular markers of long-term survival after oligometastasis-directed stereotactic body radiotherapy (SBRT).
Academic Article Rationale of technical requirements for NRG-BR001: The first NCI-sponsored trial of SBRT for the treatment of multiple metastases.
Academic Article Benchmark Credentialing Results for NRG-BR001: The First National Cancer Institute-Sponsored Trial of Stereotactic Body Radiation Therapy for Multiple Metastases.
Academic Article Promoting the Appropriate Use of Advanced Radiation Technologies in Oncology: Summary of a National Cancer Policy Forum Workshop.
Academic Article Definitive Stereotactic Body Radiotherapy (SBRT) for Extracranial Oligometastases: An International Survey of >1000 Radiation Oncologists.
Academic Article Utilization trend and regimens of hypofractionated whole breast radiation therapy in the United States.
Academic Article A feasibility study of 2-mm bolus for postmastectomy radiation therapy.
Academic Article American Association of Physicists in Medicine Task Group 263: Standardizing Nomenclatures in Radiation Oncology.
Academic Article Towards frameless maskless SRS through real-time 6DoF robotic motion compensation.
Academic Article Radiotherapy for Oligometastatic Lung Cancer.
Academic Article Classification for long-term survival in oligometastatic patients treated with ablative radiotherapy: A multi-institutional pooled analysis.
Academic Article Single-institution report of setup margins of voluntary deep-inspiration breath-hold (DIBH) whole breast radiotherapy implemented with real-time surface imaging.
Academic Article Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors.
Academic Article PMRT: Please Mind Randomized Trials.
Academic Article Rhythmic radiotherapy beats down TGF-ß.
Academic Article The Evolution of Radiation Therapy in Metastatic Breast Cancer: From Local Therapy to Systemic Agent.
Academic Article Rhythmic radiotherapy beats down TGF-ß.
Academic Article Rescue of Immunotherapy-Refractory Metastatic Merkel Cell Carcinoma With Conventionally Fractionated Radiotherapy and Concurrent Pembrolizumab.
Academic Article Elevated Radiation Therapy Toxicity in the Setting of Germline PTEN Mutation.
Academic Article Integration of radiotherapy and immunotherapy for treatment of oligometastases.
Academic Article Tumor-reprogrammed resident T cells resist radiation to control tumors.
Academic Article The Evolution (and Future) of Stereotactic Body Radiotherapy in the Treatment of Oligometastatic Disease.
Academic Article Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001.
Academic Article Clinical and Radiographic Presentations of COVID-19 Among Patients Receiving Radiation Therapy for Thoracic Malignancies.
Academic Article Coronavirus Disease 2019 Infection Prevention and Control Practices in Wuhan Radiation Therapy.
Academic Article Cytoreduction and the Optimization Of Immune Checkpoint Inhibition with Radiation Therapy.
Academic Article Improved Survival Associated with Local Tumor Response Following Multisite Radiotherapy and Pembrolizumab: Secondary Analysis of a Phase I Trial.
Academic Article A study of the dosimetric impact of daily setup variations measured with cone-beam CT on three-dimensional conformal radiotherapy for early-stage breast cancer delivered in the prone position.
Academic Article Radiation treatment planning study to investigate feasibility of delivering Immunotherapy in Combination with Ablative Radiosurgery to Ultra-High DoSes (ICARUS).
Academic Article Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity.
Academic Article Evaluation of Safety of Stereotactic Body Radiotherapy for the Treatment of Patients With Multiple Metastases: Findings From the NRG-BR001 Phase 1 Trial.
Academic Article Phase I Study of Stereotactic Body Radiotherapy plus Nivolumab and Urelumab or Cabiralizumab in Advanced Solid Tumors.
Academic Article A Phase 1 Trial of Concurrent or Sequential Ipilimumab, Nivolumab, and Stereotactic Body Radiotherapy in Patients With Stage IV NSCLC Study.
Academic Article Evaluation of Dose Distribution to Organs-at-Risk in a Prospective Phase 1 Trial of Pembrolizumab and Multisite Stereotactic Body Radiation Therapy (SBRT).
Academic Article Prospective Evaluation of Stereotactic Body Radiotherapy and Immunotherapy for Mediastinal and Hilar Lymph Node Metastases.
Academic Article Stereotactic Body Radiation Therapy and Immunotherapy in Abdominal and Pelvic Lymph Node Metastases.
Academic Article Evaluation of Initial Metastatic Tumor Location and Radiation Response to Determine Outcomes in Patients Who Received Combination Stereotactic Body Radiotherapy and Immunotherapy for NSCLC.
Academic Article Should We Target Oligometastatic EGFR-Mutated Non-Small Cell Lung Cancer With Radiotherapy Before Administering Targeted Systemic Therapy?
Academic Article Predictors of Pneumonitis in Combined Thoracic Stereotactic Body Radiation Therapy and Immunotherapy.
Academic Article Stereotactic Body Radiation Therapy for Oligometastasis: GUst Do It?
Grant NCI National Clinical Trials Network-Network Lead Academic Participating Sites
Academic Article YTHDF2 inhibition potentiates radiotherapy antitumor efficacy.
Academic Article Combined Stereotactic Body Radiation Therapy and Immune Checkpoint Inhibition for Liver Metastases: Safety and Outcomes in a Pooled Analysis of 3 Phase 1 Trials.
Academic Article Radiotherapy Enhances Metastasis Through Immune Suppression by Inducing PD-L1 and MDSC in Distal Sites.
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  • Radiotherapy