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Search Results to Steven Chmura

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One or more keywords matched the following properties of Chmura, Steven

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keywords oligometastases, immunotherapy, radioimmunotherapy,Breast Cancer, @docace911, SBRT, XBOX
overview Dr. Steven J. Chmura is an Associate Professor in the Department of Radiation and Cellular Oncology and Director of Clinical and Translational Research at The University of Chicago. Steven J. Chmura MD, PhD is the director of Clinical and Translational Research for Radiation Oncology at the University of Chicago for over a decade. He has been actively involved in both the clinical implementation of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT) and related translational and clinical research, as well as the integration of SRS and SBRT into other systemic therapies. His clinical interests include breast cancer, limited metastatic disease, immunotherapy, and technologic improvements in the delivery of radiotherapy. Dr. Chmura is a leader in the NCI cooperative groups. His work has led to the first international oligmetastatic trials through NRG Oncology examining the safety of treating lung and breast cancer patients as a Phase II/III trial examining potential improvements to progression-free survival and overall survival. Dr. Chmura's work in radio-immunology has also translated into multiple investigator-sponsored trials along with the now accruing NCI-sponsored (A091605) trial randomizing the role of SBRT combined with pembrolizumab in advanced Merkel cell carcinoma; such integration of ablative radiotherapy and immunotherapy along with advancing the search for biomarkers is currently Dr. Chmura's focus.

One or more keywords matched the following items that are connected to Chmura, Steven

Item TypeName
Concept Breast Neoplasms
Concept Immunotherapy
Academic Article Is postmastectomy radiotherapy useful in elderly women with high-risk breast cancer?
Academic Article Does the number of lymph nodes examined in patients with lymph node-negative breast carcinoma have prognostic significance?
Academic Article Calculation and prediction of the effect of respiratory motion on whole breast radiation therapy dose distributions.
Academic Article Magnetic resonance imaging identifies multifocal and multicentric disease in breast cancer patients who are eligible for partial breast irradiation.
Academic Article Stereotactic body radiotherapy for multisite extracranial oligometastases: final report of a dose escalation trial in patients with 1 to 5 sites of metastatic disease.
Academic Article Predictors of competing mortality in early breast cancer.
Academic Article Feasibility and acute toxicity of hypofractionated radiation in large-breasted patients.
Academic Article Outcomes in black patients with early breast cancer treated with breast conservation therapy.
Academic Article A prospective study of the utility of magnetic resonance imaging in determining candidacy for partial breast irradiation.
Academic Article Radiation-induced equilibrium is a balance between tumor cell proliferation and T cell-mediated killing.
Academic Article The role of surgery and ablative radiotherapy in oligometastatic breast cancer.
Academic Article Assessment of interfractional variation of the breast surface following conventional patient positioning for whole-breast radiotherapy.
Academic Article An image-guided study of setup reproducibility of postmastectomy breast cancer patients treated with inverse-planned intensity modulated radiation therapy.
Academic Article Risk of second malignancies in patients with early-stage classical Hodgkin's lymphoma treated in a modern era.
Academic Article Hypofractionated radiotherapy does not increase acute toxicity in large-breasted women: results from a prospectively collected series.
Academic Article Surgery or ablative radiotherapy for breast cancer oligometastases.
Academic Article Stereotactic body radiotherapy for oligometastatic breast cancer: a new standard of care, or a medical reversal in waiting?
Academic Article Clinical and molecular markers of long-term survival after oligometastasis-directed stereotactic body radiotherapy (SBRT).
Academic Article Rationale of technical requirements for NRG-BR001: The first NCI-sponsored trial of SBRT for the treatment of multiple metastases.
Academic Article Definitive Stereotactic Body Radiotherapy (SBRT) for Extracranial Oligometastases: An International Survey of >1000 Radiation Oncologists.
Academic Article Utilization trend and regimens of hypofractionated whole breast radiation therapy in the United States.
Academic Article A feasibility study of 2-mm bolus for postmastectomy radiation therapy.
Academic Article Putting the "BR" in SBRT.
Academic Article Single-institution report of setup margins of voluntary deep-inspiration breath-hold (DIBH) whole breast radiotherapy implemented with real-time surface imaging.
Academic Article PMRT: Please Mind Randomized Trials.
Academic Article The Evolution of Radiation Therapy in Metastatic Breast Cancer: From Local Therapy to Systemic Agent.
Academic Article Rescue of Immunotherapy-Refractory Metastatic Merkel Cell Carcinoma With Conventionally Fractionated Radiotherapy and Concurrent Pembrolizumab.
Academic Article Integration of radiotherapy and immunotherapy for treatment of oligometastases.
Academic Article The Yin and Yang of Cytoreductive SBRT in Oligometastases and Beyond.
Academic Article Tumor-reprogrammed resident T cells resist radiation to control tumors.
Academic Article Predicting intracranial progression following stereotactic radiosurgery for brain metastases: Implications for post SRS imaging.
Academic Article A Validated T Cell Radiomics Score Is Associated With Clinical Outcomes Following Multisite SBRT and Pembrolizumab.
Academic Article A study of the dosimetric impact of daily setup variations measured with cone-beam CT on three-dimensional conformal radiotherapy for early-stage breast cancer delivered in the prone position.
Academic Article The role of immunotherapy in combination with oligometastasis-directed therapy: a narrative review.
Academic Article Radiation treatment planning study to investigate feasibility of delivering Immunotherapy in Combination with Ablative Radiosurgery to Ultra-High DoSes (ICARUS).
Academic Article Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity.
Academic Article Evaluation of Dose Distribution to Organs-at-Risk in a Prospective Phase 1 Trial of Pembrolizumab and Multisite Stereotactic Body Radiation Therapy (SBRT).
Academic Article CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer.
Academic Article Prospective Evaluation of Stereotactic Body Radiotherapy and Immunotherapy for Mediastinal and Hilar Lymph Node Metastases.
Academic Article Stereotactic Body Radiation Therapy and Immunotherapy in Abdominal and Pelvic Lymph Node Metastases.
Academic Article Evaluation of Initial Metastatic Tumor Location and Radiation Response to Determine Outcomes in Patients Who Received Combination Stereotactic Body Radiotherapy and Immunotherapy for NSCLC.

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  • oligometastases
  • immunotherapy
  • radioimmunotherapy
  • Breast Cancer
  • docace911
  • SBRT
  • XBOX