Item Type | Name |
Concept
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Mice, Inbred C3H
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Concept
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Mice, Inbred Strains
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Concept
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Mice, Transgenic
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Nude
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Concept
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Mice, Inbred DBA
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Concept
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Mice, Knockout
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Concept
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Mice, Inbred MRL lpr
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Concept
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Mice, Congenic
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Concept
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Mice
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Concept
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Mice, Mutant Strains
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Concept
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Mice, SCID
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Concept
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Mice, Inbred NOD
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Academic Article
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Regulation of B cell function by the immunosuppressive agent leflunomide.
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Academic Article
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Vav in natural killer cells is tyrosine phosphorylated upon cross-linking of Fc gamma RIIIA and is constitutively associated with a serine/threonine kinase.
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Academic Article
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Two activities of the immunosuppressive metabolite of leflunomide, A77 1726. Inhibition of pyrimidine nucleotide synthesis and protein tyrosine phosphorylation.
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Academic Article
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Effect of gene gun-mediated CTLA4IG and Fas ligand gene transfection on concordant xenogeneic islet graft rejection.
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Academic Article
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Gene gun-mediated gene transfer and expression in rat islets.
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Academic Article
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The immunosuppressive metabolite of leflunomide, A77 1726, affects murine T cells through two biochemical mechanisms.
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Academic Article
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Successful xenotransplantation of adult porcine islets in NOD and BALB/c mice with leflunomide and cyclosporine.
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Academic Article
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Leflunomide-based immunosuppression for porcine islet xenotransplantation.
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Academic Article
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In vitro and in vivo mechanisms of action of the antiproliferative and immunosuppressive agent, brequinar sodium.
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Academic Article
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In vivo activity of leflunomide: pharmacokinetic analyses and mechanism of immunosuppression.
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Academic Article
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Control of lymphoproliferative and autoimmune disease in MRL-lpr/lpr mice by brequinar sodium: mechanisms of action.
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Academic Article
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Inhibition of JAK3 and STAT6 tyrosine phosphorylation by the immunosuppressive drug leflunomide leads to a block in IgG1 production.
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Academic Article
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Differential effect of leflunomide on concordant xenogeneic islet graft rejection and recurrence of autoimmune diabetes.
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Academic Article
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Immunosuppression preventing concordant xenogeneic islet graft rejection is not sufficient to prevent recurrence of autoimmune diabetes in nonobese diabetic mice.
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Academic Article
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In vitro and in vivo antitumor activity of a novel immunomodulatory drug, leflunomide: mechanisms of action.
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Academic Article
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Tolerance of T-independent xeno-antibody responses in the hamster-to-rat xenotransplantation model is species-restricted but not tissue-specific.
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Academic Article
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Anti-galactose-alpha(1,3)Galactose antibody production in alpha1, 3-galactosyltransferase gene knockout mice after xeno- and allotransplantation.
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Academic Article
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Non-depleting anti-CD4, but not anti-CD8, antibody induces long-term survival of xenogeneic and allogeneic hearts in alpha1,3-galactosyltransferase knockout (GT-Ko) mice.
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Academic Article
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Differential immune response to carbohydrate epitopes on allo- and xenografts: implications for accommodation.
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Academic Article
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Onset of accumulation of PrPres in murine ME7 scrapie in relation to pathological and PrP immunohistochemical changes.
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Academic Article
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Differential immune responses to alpha-gal epitopes on xenografts and allografts: implications for accommodation in xenotransplantation.
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Academic Article
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Acute xenograft rejection mediated by antibodies produced independently of TH1/TH2 cytokine profiles.
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Academic Article
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Nondepleting anti-CD4 but not anti-CD8 antibody induces long-term survival of xenogeneic and allogeneic hearts in alpha1, 3-galactosyl-transferase knock-out mice.
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Academic Article
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Intact active bone transplantation synergizes with anti-CD40 ligand therapy to induce B cell tolerance.
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Academic Article
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CTLA-41g in combination with anti-CD40L prolongs xenograft survival and inhibits anti-gal ab production in GT-Ko mice.
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Academic Article
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Development and characterization of anti-Gal B cell receptor transgenic Gal-/- mice.
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Academic Article
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Allograft tolerance induced by intact active bone co-transplantation and anti-CD40L monoclonal antibody therapy.
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Academic Article
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Direct killing of xenograft cells by CD8+ T cells of discordant xenograft recipients.
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Academic Article
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The in vitro and in vivo effects of anti-galactose antibodies on endothelial cell activation and xenograft rejection.
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Academic Article
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Role of CD4+ and CD8+ T cells in the rejection of concordant pancreas xenografts.
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Academic Article
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Mouse-heart grafts expressing an incompatible carbohydrate antigen. II. Transition from accommodation to tolerance.
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Academic Article
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Evidence that tilapia islets do not express alpha-(1,3)gal: implications for islet xenotransplantation.
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Academic Article
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Cutting Edge: NK cells mediate IgG1-dependent hyperacute rejection of xenografts.
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Academic Article
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A mouse model for studying intrahepatic islet transplantation.
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Academic Article
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Cutting edge: Cbl-b: one of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation.
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Academic Article
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Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors.
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Academic Article
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Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration.
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Academic Article
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Liver ischemia contributes to early islet failure following intraportal transplantation: benefits of liver ischemic-preconditioning.
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Academic Article
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Recovery of islet beta-cell function in streptozotocin- induced diabetic mice: an indirect role for the spleen.
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Academic Article
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Hyperacute rejection by anti-Gal IgG1, IgG2a, and IgG2b is dependent on complement and Fc-gamma receptors.
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Academic Article
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TLR signals promote IL-6/IL-17-dependent transplant rejection.
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Academic Article
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Glycemic control promotes pancreatic beta-cell regeneration in streptozotocin-induced diabetic mice.
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Academic Article
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Seeing is believing: how the MIP-luc mouse can advance the field of islet transplantation and ß-cell regeneration.
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Academic Article
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Alloantibodies prevent the induction of transplantation tolerance by enhancing alloreactive T cell priming.
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Academic Article
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Peripheral deletion of mature alloreactive B cells induced by costimulation blockade.
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Academic Article
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CD4+ T cells are sufficient to elicit allograft rejection and major histocompatibility complex class I molecule is required to induce recurrent autoimmune diabetes after pancreas transplantation in mice.
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Academic Article
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The Mll partial tandem duplication: differential, tissue-specific activity in the presence or absence of the wild-type allele.
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Academic Article
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Memory alloreactive B cells and alloantibodies prevent anti-CD154-mediated allograft acceptance.
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Academic Article
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Expression of complement regulatory proteins in accommodated xenografts induced by anti-alpha-Gal IgG1 in a rat-to-mouse model.
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Academic Article
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IL-6 induced by Staphylococcus aureus infection prevents the induction of skin allograft acceptance in mice.
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Academic Article
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Experimental models of B cell tolerance in transplantation.
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Academic Article
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Evidence for a dithiol-activated signaling pathway in natural killer cell avidity regulation of leukocyte function antigen-1: structural requirements and relationship to phorbol ester- and CD16-triggered pathways.
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Academic Article
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Modulating adaptive immune responses to peptide self-assemblies.
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Academic Article
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Self-assembled peptide nanofibers raising durable antibody responses against a malaria epitope.
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Academic Article
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TLR engagement prevents transplantation tolerance.
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Academic Article
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Inhibition of protein tyrosine phosphorylation in T cells by a novel immunosuppressive agent, leflunomide.
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Academic Article
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Prevention of allograft tolerance by bacterial infection with Listeria monocytogenes.
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Academic Article
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Long-term control of alloreactive B cell responses by the suppression of T cell help.
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Academic Article
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Infection with the intracellular bacterium, Listeria monocytogenes, overrides established tolerance in a mouse cardiac allograft model.
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Academic Article
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Effect of leflunomide and cyclosporine on concordant xenogeneic islet transplantation in streptozotocin-induced and autoimmune diabetic mice.
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Academic Article
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In vivo mechanism by which leflunomide controls lymphoproliferative and autoimmune disease in MRL/MpJ-lpr/lpr mice.
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Academic Article
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Induction of species-specific host accommodation in the hamster-to-rat xenotransplantation model.
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Academic Article
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Efficacy of FK506, leflunomide, anti-CD4, and CTLA4IG treatments in rat to mouse pancreas xenograft transplantation.
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Academic Article
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Anti-galactose-alpha(1,3) galactose antibody production in alpha1,3-galactosyltransferase gene knockout mice after xeno and allo transplantation.
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Academic Article
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Lewis rat pancreas, but not cardiac xenografts, are resistant to anti-gal antibody mediated hyperacute rejection.
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Academic Article
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The structure of anti-Gal immunoglobulin genes in naïve and stimulated Gal knockout mice.
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Academic Article
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IFN-gamma production is specifically regulated by IL-10 in mice made tolerant with anti-CD40 ligand antibody and intact active bone.
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Academic Article
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Bioluminescence imaging visualizes activation of nuclear factor-kappaB in mouse cardiac transplantation.
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Academic Article
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Nonimmune lymphocyte-macrophage interaction. I. Quantification by an automated colorimetric assay.
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Academic Article
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Enhancing pancreatic Beta-cell regeneration in vivo with pioglitazone and alogliptin.
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Academic Article
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Local inflammation exacerbates the severity of Staphylococcus aureus skin infection.
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Academic Article
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Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4.
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Academic Article
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Protective immunity against recurrent Staphylococcus aureus skin infection requires antibody and interleukin-17A.
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Academic Article
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Lessons and limits of mouse models.
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Academic Article
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A self-adjuvanting supramolecular vaccine carrying a folded protein antigen.
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Academic Article
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B cells assist allograft rejection in the deficiency of protein kinase c-theta.
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Academic Article
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Gut microbiota elicits a protective immune response against malaria transmission.
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Academic Article
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Reversing endogenous alloreactive B cell GC responses with anti-CD154 or CTLA-4Ig.
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Academic Article
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Cell surface receptors for sulphated polysaccharides: a potential marker for macrophage subsets.
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Academic Article
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Gradated assembly of multiple proteins into supramolecular nanomaterials.
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Academic Article
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Titrating T-cell epitopes within self-assembled vaccines optimizes CD4+ helper T cell and antibody outputs.
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Academic Article
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The use of self-adjuvanting nanofiber vaccines to elicit high-affinity B cell responses to peptide antigens without inflammation.
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Academic Article
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Spontaneous restoration of transplantation tolerance after acute rejection.
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Academic Article
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Proteomic Identification of saeRS-Dependent Targets Critical for Protective Humoral Immunity against Staphylococcus aureus Skin Infection.
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Academic Article
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Cutting Edge: CTLA-4Ig Inhibits Memory B Cell Responses and Promotes Allograft Survival in Sensitized Recipients.
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Academic Article
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High-Fat Diet-Induced Obesity Enhances Allograft Rejection.
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Academic Article
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The composition of the microbiota modulates allograft rejection.
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Academic Article
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Cytotoxicity of prion protein peptide (PrP106-126) differs in mechanism from the cytotoxic activity of the Alzheimer's disease amyloid peptide, A beta 25-35.
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Academic Article
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Delayed Cytotoxic T Lymphocyte-Associated Protein 4-Immunoglobulin Treatment Reverses Ongoing Alloantibody Responses and Rescues Allografts From Acute Rejection.
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Academic Article
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Tracing Donor-MHC Class II Reactive B cells in Mouse Cardiac Transplantation: Delayed CTLA4-Ig Treatment Prevents Memory Alloreactive B-Cell Generation.
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Academic Article
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Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell Central Tolerance.
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Academic Article
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Adoptive Transfer of Tracer-Alloreactive CD4+ T Cell Receptor Transgenic T Cells Alters the Endogenous Immune Response to an Allograft.
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Academic Article
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Erosion of Transplantation Tolerance After Infection.
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Academic Article
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Transplantation tolerance: don't forget about the B cells.
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Academic Article
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Tracking of TCR-Transgenic T Cells Reveals That Multiple Mechanisms Maintain Cardiac Transplant Tolerance in Mice.
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Academic Article
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Evolving Approaches in the Identification of Allograft-Reactive T and B Cells in Mice and Humans.
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Academic Article
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Successful Treatment of T Cell-Mediated Acute Rejection with Delayed CTLA4-Ig in Mice.
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Academic Article
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Active immunotherapy for TNF-mediated inflammation using self-assembled peptide nanofibers.
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Academic Article
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The IRF4 Gene Regulatory Module Functions as a Read-Write Integrator to Dynamically Coordinate T Helper Cell Fate.
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Academic Article
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Nonimmune lymphocyte-macrophage interaction. II. Evidence that the interaction involves sulfated polysaccharide recognition.
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Academic Article
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Activation of extracellular signal-regulated kinases potentiates hemin toxicity in astrocyte cultures.
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Academic Article
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Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8+ T cell responses.
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Academic Article
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Distinct Graft-Specific TCR Avidity Profiles during Acute Rejection and Tolerance.
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Academic Article
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Skin-restricted commensal colonization accelerates skin graft rejection.
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Academic Article
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Resilience of T cell-intrinsic dysfunction in transplantation tolerance.
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Academic Article
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B cells as antigen-presenting cells in transplantation rejection and tolerance.
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Academic Article
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Enabling sublingual peptide immunization with molecular self-assemblies.
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Academic Article
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Reversing donor-specific antibody responses and antibody-mediated rejection with bortezomib and belatacept in mice and kidney transplant recipients.
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Academic Article
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Inhibition of protective immunity against Staphylococcus aureus infection by MHC-restricted immunodominance is overcome by vaccination.
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Academic Article
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Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells.
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Academic Article
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Pregnancy-induced humoral sensitization overrides T cell tolerance to fetus-matched allografts in mice.
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Academic Article
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Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection.
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Academic Article
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Oral alloantigen exposure promotes donor-specific tolerance in a mouse model of minor-mismatched skin transplantation.
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Academic Article
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Linked sensitization by memory CD4+ T cells prevents costimulation blockade-induced transplantation tolerance.
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Academic Article
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Host-versus-commensal immune responses participate in the rejection of colonized solid organ transplants.
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Academic Article
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Beyond Adaptive Alloreactivity: Contribution of Innate B Cells to Allograft Inflammation and Rejection.
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Academic Article
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From bench to bedside: reversing established antibody responses and desensitization.
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Academic Article
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Tissue specificity drives protective immunity against Staphylococcus aureus infection.
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Academic Article
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Reduced Satb1 expression predisposes CD4+ T conventional cells to Treg suppression and promotes transplant survival.
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Academic Article
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Transcriptionally Distinct B Cells Infiltrate Allografts After Kidney Transplantation.
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Academic Article
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Donor programmed cell death 1 ligand 1 is required for organ transplant tolerance in major histocompatibility complex-mismatched mixed chimeras although programmed cell death 1 ligand 1 and major histocompatibility complex class II are not required for inducing chimerism.
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Academic Article
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MHC Tetramers Specifically Identify High- and Low-avidity Donor-specific B Cells in Transplantation Tolerance and Rejection.
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Academic Article
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Heterogeneity in allospecific T cell function in transplant-tolerant hosts determines susceptibility to rejection following infection.
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Academic Article
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A novel triptolide analog downregulates NF-?B and induces mitochondrial apoptosis pathways in human pancreatic cancer.
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Academic Article
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Lung cDC1 and cDC2 dendritic cells priming naive CD8+ T cells in situ prior to migration to draining lymph nodes.
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Academic Article
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IL-21-producing effector Tfh cells promote B cell alloimmunity in lymph nodes and kidney allografts.
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Academic Article
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Low-affinity CD8+ T cells provide interclonal help to high-affinity CD8+ T cells to augment alloimmunity.
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Academic Article
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Advancing mouse models for transplantation research.
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Academic Article
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Pregnancy dedifferentiates memory CD8+ T cells into hypofunctional cells with exhaustion-enriched programs.
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