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One or more keywords matched the following properties of Claud, Erika C.
keywords Preterm Infant
overview Dr. Claud is a physician scientist who intended to be a full time clinician but discovered a passion for answering questions through laboratory investigation. She is committed to the questions being explored in her laboratory but also to encouraging medical students and trainees to consider research as an essential and feasible means of improving patient care. Dr. Claud is a Professor in the Department of Pediatrics, Section of Neonatology, and the Department of Medicine, Section of Gastroenterology. She received her combined undergraduate and medical degree at Northwestern University through the six year Honors Program in Medical Education, and then completed her Residency in Pediatrics at Children’s Memorial Hospital in Chicago. After spending 18 months in rural Kenya as a missionary physician, she returned to Chicago to complete her Neonatology Fellowship at Children’s Memorial Hospital. Following her clinical fellowship she was recruited to Harvard Medical School where she held a clinical position at The Boston Children’s Hospital and completed a research fellowship at Massachusetts General Hospital. She joined the faculty of the University of Chicago in 2004. She is NIH funded to investigate the role of microbes in intestinal development of the preterm infant and leads the MIND (Microbiome in Neonatal Development) cohort. The interaction between the intestine and its resident microbiota is a complex relationship with risk and benefit for the host. Perturbations in environmental cues or altered patterns of microbial selection can affect health and increase risk of disease in susceptible individuals. The simple microbial communities and limited environmental variation of the preterm infant provide a unique model in which to investigate microbial perturbations. Her laboratory utilizes state-of-the-art experimental approaches including: 16S rRNA and shotgun metagenomic analyses of the microbiome, gnotobiotic mouse models, rodent models of Neonatal Necrotizing Enterocolitis, as well as cell culture models of immature and mature intestine to investigate the health impact of the microbiome on health outcomes of preterm infants. She is co-director of the Basic Science Track within the Scholarship and Discovery Program of the Pritzker School of Medicine and Faculty Co-Chair Pritzker School of Medicine Summer Research Program. She is also Director of Neonatology Research and a member of the Faculty Leadership Cabinet for the Duchossois Family Institute.
One or more keywords matched the following items that are connected to Claud, Erika C.
Item TypeName
Concept Infant, Premature
Concept Infant, Premature, Diseases
Academic Article Bacterial colonization, probiotics, and necrotizing enterocolitis.
Academic Article 16S rRNA gene-based analysis of fecal microbiota from preterm infants with and without necrotizing enterocolitis.
Academic Article Probiotics and neonatal necrotizing enterocolitis.
Academic Article Bacterial community structure and functional contributions to emergence of health or necrotizing enterocolitis in preterm infants.
Academic Article Transcriptional modulation of intestinal innate defense/inflammation genes by preterm infant microbiota in a humanized gnotobiotic mouse model.
Academic Article Oropharyngeal administration of mother's colostrum, health outcomes of premature infants: study protocol for a randomized controlled trial.
Academic Article Epigenome-Microbiome crosstalk: A potential new paradigm influencing neonatal susceptibility to disease.
Academic Article The Developing Microbiome of the Preterm Infant.
Academic Article Preterm infant gut microbiota affects intestinal epithelial development in a humanized microbiome gnotobiotic mouse model.
Academic Article Association of the gut microbiota mobilome with hospital location and birth weight in preterm infants.
Grant Early Enterocyte Injury in Neonatal Necrotizing Enterocolitis
Academic Article Connection between gut microbiome and brain development in preterm infants.
Academic Article Effects of Intestinal Microbiota on Brain Development in Humanized Gnotobiotic Mice.
Academic Article Intrauterine Inflammation, Epigenetics, and Microbiome Influences on Preterm Infant Health.
Academic Article Necrotizing Enterocolitis and the Preterm Infant Microbiome.
Academic Article Necrotizing Enterocolitis Pathophysiology: How Microbiome Data Alter Our Understanding.
Grant Immature intestinal NF-kB regulation, probiotics, and necrotizing enterocolitis
Grant The microbiome as a potential mediator of socio-economic disparities in preterm infant neurodevelopmental trajectories from NICU discharge to school age
Grant Preterm infant susceptibility to NEC due to early intestinal microbiome function
Grant Use of Probiotic Conditioned Media to Protect Against Necrotizing Enterocolitis
Academic Article The early gut microbiome could protect against severe retinopathy of prematurity.
Academic Article Effect of Antibiotic Use Within First 48 Hours of Life on the Preterm Infant Microbiome: A Randomized Clinical Trial.
Academic Article The microbiome, guard or threat to infant health.
Academic Article Bacteroidota and Lachnospiraceae integration into the gut microbiome at key time points in early life are linked to infant neurodevelopment.
Academic Article Early preterm infant microbiome impacts adult learning.
Academic Article A randomized controlled trial of oropharyngeal therapy with mother's own milk for premature infants.
Academic Article Correction to: A randomized controlled trial of oropharyngeal therapy with mother's own milk for premature infants.
Academic Article Neurodevelopmental outcome of infants who develop necrotizing enterocolitis: The gut-brain axis.
Academic Article Gut Microbiome-Brain Axis as an Explanation for the Risk of Poor Neurodevelopment Outcome in Preterm Infants with Necrotizing Enterocolitis.
Academic Article The Impact of Maternal Probiotics on Intestinal Vitamin D Receptor Expression in Early Life.
Academic Article Microbiota from Preterm Infants Who Develop Necrotizing Enterocolitis Drives the Neurodevelopment Impairment in a Humanized Mouse Model.
Academic Article A digital twin of the infant microbiome to predict neurodevelopmental deficits.
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  • Preterm Infant