Item Type | Name |
Concept
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Gene Expression Regulation
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Concept
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Gene Expression Regulation, Enzymologic
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Concept
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Gene Expression Regulation, Leukemic
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Concept
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Gene Expression Regulation, Neoplastic
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Academic Article
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Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
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Academic Article
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Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling.
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Academic Article
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Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells.
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Academic Article
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Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
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Academic Article
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Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
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Academic Article
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Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma.
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Academic Article
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Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma.
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Academic Article
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Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
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Academic Article
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Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage-independent growth properties and impact on global gene expression in esophageal carcinoma.
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Academic Article
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Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
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Academic Article
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Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
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Academic Article
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Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese.
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Academic Article
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Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression.
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Academic Article
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Identification of nine novel loci associated with white blood cell subtypes in a Japanese population.
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Academic Article
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Characterization of a cleavage stimulation factor, 3' pre-RNA, subunit 2, 64 kDa (CSTF2) as a therapeutic target for lung cancer.
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Academic Article
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ORAI1 genetic polymorphisms associated with the susceptibility of atopic dermatitis in Japanese and Taiwanese populations.
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Academic Article
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Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
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Academic Article
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Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy.
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Academic Article
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Polymorphic human insulin-responsive glucose-transporter gene on chromosome 17p13.
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Academic Article
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Comparison of gene-expression profiles between diffuse- and intestinal-type gastric cancers using a genome-wide cDNA microarray.
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Academic Article
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Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray.
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Academic Article
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Genome-wide gene-expression profiles of breast-cancer cells purified with laser microbeam microdissection: identification of genes associated with progression and metastasis.
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Academic Article
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Genome-wide gene expression profile analysis of esophageal squamous cell carcinomas.
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Academic Article
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Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4.
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Academic Article
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Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray.
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Academic Article
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Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
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Academic Article
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Genome-wide analysis of gene expression in intestinal-type gastric cancers using a complementary DNA microarray representing 23,040 genes.
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Academic Article
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Molecular features of hormone-refractory prostate cancer cells by genome-wide gene expression profiles.
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Academic Article
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Comparative profiling of serum glycoproteome by sequential purification of glycoproteins and 2-nitrobenzensulfenyl (NBS) stable isotope labeling: a new approach for the novel biomarker discovery for cancer.
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Academic Article
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Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.
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Academic Article
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Molecular features of triple negative breast cancer cells by genome-wide gene expression profiling analysis.
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Academic Article
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A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
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Academic Article
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Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.
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Academic Article
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EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth.
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Academic Article
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Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and PINs.
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Academic Article
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Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.
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Academic Article
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Stanniocalcin 2 overexpression in castration-resistant prostate cancer and aggressive prostate cancer.
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Academic Article
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A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities.
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Academic Article
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Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis.
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Academic Article
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Genome-wide gene expression profiles of clear cell renal cell carcinoma: identification of molecular targets for treatment of renal cell carcinoma.
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Academic Article
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Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis.
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Academic Article
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Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus.
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Academic Article
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TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
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Academic Article
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Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.
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Academic Article
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Prediction of sensitivity to STI571 among chronic myeloid leukemia patients by genome-wide cDNA microarray analysis.
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Academic Article
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Genome-wide analysis of organ-preferential metastasis of human small cell lung cancer in mice.
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Academic Article
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Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes.
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Academic Article
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A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis.
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Academic Article
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Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.
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Academic Article
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Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells.
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Academic Article
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The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
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Academic Article
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Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
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Academic Article
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p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway.
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Academic Article
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Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair.
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Academic Article
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Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells.
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Academic Article
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Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma.
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Academic Article
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Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell.
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Academic Article
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Comparison of gene expression profiles between Opisthorchis viverrini and non-Opisthorchis viverrini associated human intrahepatic cholangiocarcinoma.
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Academic Article
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DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway.
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Academic Article
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Over-expression of cysteine proteinase inhibitor cystatin 6 promotes pancreatic cancer growth.
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Academic Article
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Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis.
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Academic Article
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Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.
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Academic Article
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Classification of sensitivity or resistance of cervical cancers to ionizing radiation according to expression profiles of 62 genes selected by cDNA microarray analysis.
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Academic Article
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The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.
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Academic Article
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Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.
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Academic Article
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RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer.
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Academic Article
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Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity.
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Academic Article
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Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
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Academic Article
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Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G(1)/S transition.
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Academic Article
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Microarray analysis of gene-expression profiles in diffuse large B-cell lymphoma: identification of genes related to disease progression.
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Academic Article
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Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma.
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Academic Article
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Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas.
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Academic Article
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Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma.
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Academic Article
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Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.
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Academic Article
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Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinoma.
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Academic Article
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CLCA2 as a p53-inducible senescence mediator.
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Academic Article
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Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
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Academic Article
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Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis.
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Academic Article
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WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
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Academic Article
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Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.
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Academic Article
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The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.
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Academic Article
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RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation.
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Academic Article
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Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.
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Academic Article
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Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
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Academic Article
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Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
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Academic Article
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The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination.
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Academic Article
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Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer.
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Academic Article
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Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer.
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Academic Article
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Enhanced SMYD3 expression is essential for the growth of breast cancer cells.
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Academic Article
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Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population.
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Academic Article
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Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.
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Academic Article
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Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
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Academic Article
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Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.
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Academic Article
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Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles.
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Academic Article
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Expression profiles of metastatic brain tumor from lung adenocarcinomas on cDNA microarray.
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Academic Article
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The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
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Academic Article
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Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappaB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure.
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Academic Article
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Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target.
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Academic Article
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VAV3 mediates resistance to breast cancer endocrine therapy.
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Academic Article
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The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
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Academic Article
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Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
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Academic Article
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Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1.
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Academic Article
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A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells.
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Academic Article
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Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
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Academic Article
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Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.
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Academic Article
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A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.
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Academic Article
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Serial analysis of gene expression in progressing and regressing mouse tumors implicates the involvement of RANTES and TARC in antitumor immune responses.
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Academic Article
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Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
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Academic Article
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Gene expression profiles of small-cell lung cancers: molecular signatures of lung cancer.
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Academic Article
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The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
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Academic Article
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Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.
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Academic Article
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SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
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Academic Article
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Expression profile analysis of colon cancer cells in response to sulindac or aspirin.
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Academic Article
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Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers.
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Academic Article
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Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas.
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Academic Article
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Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
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Academic Article
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Molecular target therapy for synovial sarcoma.
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Academic Article
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Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer.
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Academic Article
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Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.
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Academic Article
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SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells.
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Academic Article
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T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.
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Academic Article
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Regulation of iron homeostasis by the p53-ISCU pathway.
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Academic Article
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SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells.
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Academic Article
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Elevated expression of protein regulator of cytokinesis 1, involved in the growth of breast cancer cells.
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Academic Article
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HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL.
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Academic Article
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Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.
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Academic Article
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From cancer genomics to thoracic oncology: discovery of new biomarkers and therapeutic targets for lung and esophageal carcinoma.
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Academic Article
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Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity.
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Academic Article
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Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma.
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Academic Article
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Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
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Academic Article
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Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown.
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Academic Article
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Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors.
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Academic Article
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WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck.
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Academic Article
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Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes.
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Academic Article
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Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer.
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Academic Article
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Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer.
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Academic Article
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The Transcriptional Landscape of p53 Signalling Pathway.
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Academic Article
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Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.
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Academic Article
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Characterization of the T-Cell Receptor Repertoire and Immune Microenvironment in Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck.
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Academic Article
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miR-125b-1 and miR-378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer.
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Academic Article
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Critical Role of Estrogen Receptor Alpha O-Glycosylation by N-Acetylgalactosaminyltransferase 6 (GALNT6) in Its Nuclear Localization in Breast Cancer Cells.
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Academic Article
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Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21.
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Academic Article
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Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma.
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Academic Article
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MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
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Academic Article
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The GALNT6-LGALS3BP axis promotes breast cancer cell growth.
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Academic Article
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Enhancement of Migration and Invasion of Gastric Cancer Cells by IQGAP3.
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Academic Article
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Genome-wide association study of epilepsy in a Japanese population identified an associated region at chromosome 12q24.
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