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Search Results to Yusuke Nakamura

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One or more keywords matched the following items that are connected to Nakamura, Yusuke

Item TypeName
Concept Cell Line, Tumor
Academic Article Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
Academic Article Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells.
Academic Article Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
Academic Article Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
Academic Article Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma.
Academic Article Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.
Academic Article Expression of novel molecules, MICAL2-PV (MICAL2 prostate cancer variants), increases with high Gleason score and prostate cancer progression.
Academic Article Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke.
Academic Article Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.
Academic Article Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
Academic Article Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
Academic Article Characterization of a cleavage stimulation factor, 3' pre-RNA, subunit 2, 64 kDa (CSTF2) as a therapeutic target for lung cancer.
Academic Article IRX4 at 5p15 suppresses prostate cancer growth through the interaction with vitamin D receptor, conferring prostate cancer susceptibility.
Academic Article Activation of placenta-specific transcription factor distal-less homeobox 5 predicts clinical outcome in primary lung cancer patients.
Academic Article Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression.
Academic Article Identification of Epstein-Barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer.
Academic Article Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray.
Academic Article Critical roles of mucin 1 glycosylation by transactivated polypeptide N-acetylgalactosaminyltransferase 6 in mammary carcinogenesis.
Academic Article Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
Academic Article Involvement of C12orf32 overexpression in breast carcinogenesis.
Academic Article Genes associated with liver metastasis of colon cancer, identified by genome-wide cDNA microarray.
Academic Article A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer.
Academic Article Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
Academic Article Serum REG4 level is a predictive biomarker for the response to preoperative chemoradiotherapy in patients with pancreatic cancer.
Academic Article Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.
Academic Article EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth.
Academic Article Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.
Academic Article C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.
Academic Article Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression.
Academic Article Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
Academic Article Stanniocalcin 2 overexpression in castration-resistant prostate cancer and aggressive prostate cancer.
Academic Article MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells.
Academic Article Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis.
Academic Article Genome-wide gene expression profiles of clear cell renal cell carcinoma: identification of molecular targets for treatment of renal cell carcinoma.
Academic Article Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer.
Academic Article Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis.
Academic Article Overexpression of the potential kinase serine/ threonine/tyrosine kinase 1 (STYK 1) in castration-resistant prostate cancer.
Academic Article Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis.
Academic Article Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells.
Academic Article Identification of a functional variant in the MICA promoter which regulates MICA expression and increases HCV-related hepatocellular carcinoma risk.
Academic Article 5alphaDH-DOC (5alpha-dihydro-deoxycorticosterone) activates androgen receptor in castration-resistant prostate cancer.
Academic Article The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
Academic Article Critical function for nuclear envelope protein TMEM209 in human pulmonary carcinogenesis.
Academic Article Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
Academic Article p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway.
Academic Article Crosstalk of EDA-A2/XEDAR in the p53 signaling pathway.
Academic Article Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells.
Academic Article Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell.
Academic Article Over-expression of cysteine proteinase inhibitor cystatin 6 promotes pancreatic cancer growth.
Academic Article Activation of CDCA1-KNTC2, members of centromere protein complex, involved in pulmonary carcinogenesis.
Academic Article The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.
Academic Article The neuromedin U-growth hormone secretagogue receptor 1b/neurotensin receptor 1 oncogenic signaling pathway as a therapeutic target for lung cancer.
Academic Article ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
Academic Article Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy.
Academic Article Non-transmissible Sendai virus encoding granulocyte macrophage colony-stimulating factor is a novel and potent vector system for producing autologous tumor vaccines.
Academic Article Aberrant laminin beta3 isoforms downstream of EWS-ETS fusion genes in Ewing family tumors.
Academic Article Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.
Academic Article In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy.
Academic Article Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).
Academic Article WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.
Academic Article RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer.
Academic Article Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity.
Academic Article Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells.
Academic Article Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
Academic Article Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis.
Academic Article Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma.
Academic Article Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis.
Academic Article Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas.
Academic Article Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma.
Academic Article Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.
Academic Article Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
Academic Article PCOTH, a novel gene overexpressed in prostate cancers, promotes prostate cancer cell growth through phosphorylation of oncoprotein TAF-Ibeta/SET.
Academic Article Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas.
Academic Article Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis.
Academic Article Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.
Academic Article Plakophilin 3 oncogene as prognostic marker and therapeutic target for lung cancer.
Academic Article WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
Academic Article Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma.
Academic Article A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis.
Academic Article The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.
Academic Article Identification of immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas.
Academic Article A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
Academic Article Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer.
Academic Article Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation.
Academic Article Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
Academic Article Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
Academic Article The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination.
Academic Article Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.
Academic Article Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer.
Academic Article Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10.
Academic Article MRG-binding protein contributes to colorectal cancer development.
Academic Article Gamma-aminobutyric acid (GABA) stimulates pancreatic cancer growth through overexpressing GABAA receptor pi subunit.
Academic Article Identification of an HLA-A2-restricted epitope peptide derived from hypoxia-inducible protein 2 (HIG2).
Academic Article Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.
Academic Article Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
Academic Article Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.
Academic Article Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.
Academic Article Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
Academic Article Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses.
Academic Article Critical roles of T-LAK cell-originated protein kinase in cytokinesis.
Academic Article The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
Academic Article Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target.
Academic Article VAV3 mediates resistance to breast cancer endocrine therapy.
Academic Article The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
Academic Article Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
Academic Article Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors.
Academic Article Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1.
Academic Article A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability.
Academic Article Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
Academic Article Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray.
Academic Article Serial analysis of gene expression in progressing and regressing mouse tumors implicates the involvement of RANTES and TARC in antitumor immune responses.
Academic Article Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
Academic Article Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.
Academic Article The DNA binding site specificity and antiproliferative property of ternary Pt(II) and Zn(II) complexes of phenanthroline and N,N'-ethylenediaminediacetic acid.
Academic Article The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
Academic Article Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.
Academic Article Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
Academic Article Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy.
Academic Article Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN.
Academic Article Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas.
Academic Article FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.
Academic Article Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas.
Academic Article Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
Academic Article PDZ-binding kinase/T-LAK cell-originated protein kinase, a putative cancer/testis antigen with an oncogenic activity in breast cancer.
Academic Article TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis.
Academic Article Oncogenic role of MPHOSPH1, a cancer-testis antigen specific to human bladder cancer.
Academic Article Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.
Academic Article SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells.
Academic Article Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy.
Academic Article Identification of COX17 as a therapeutic target for non-small cell lung cancer.
Academic Article Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer.
Academic Article Regulation of iron homeostasis by the p53-ISCU pathway.
Academic Article PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP.
Academic Article SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells.
Academic Article Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating rho-family GTPases.
Academic Article Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
Academic Article HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL.
Academic Article Germline PARP4 mutations in patients with primary thyroid and breast cancers.
Academic Article Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway.
Academic Article Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10: therapeutic efficacy largely depends on radiosensitivity.
Academic Article Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown.
Academic Article Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
Academic Article Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
Academic Article Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
Academic Article Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors.
Academic Article Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.
Academic Article The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy.
Academic Article T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer.
Academic Article GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
Academic Article Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.
Academic Article Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells.
Academic Article Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.
Academic Article The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
Academic Article a-particle therapy for synovial sarcoma in the mouse using an astatine-211-labeled antibody against frizzled homolog 10.
Academic Article Critical Role of Estrogen Receptor Alpha O-Glycosylation by N-Acetylgalactosaminyltransferase 6 (GALNT6) in Its Nuclear Localization in Breast Cancer Cells.
Academic Article Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma.
Academic Article MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
Academic Article Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.
Academic Article The GALNT6-LGALS3BP axis promotes breast cancer cell growth.
Academic Article Enhancement of Migration and Invasion of Gastric Cancer Cells by IQGAP3.
Academic Article High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo.
Academic Article Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer.
Academic Article FZD10-targeted a-radioimmunotherapy with 225 Ac-labeled OTSA101 achieves complete remission in a synovial sarcoma model.

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