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Search Results to Yusuke Nakamura

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One or more keywords matched the following items that are connected to Nakamura, Yusuke

Item TypeName
Concept Myosin-Light-Chain Kinase
Concept Protein-Tyrosine Kinases
Concept Phosphotransferases (Alcohol Group Acceptor)
Concept Mitogen-Activated Protein Kinases
Concept Receptor Protein-Tyrosine Kinases
Concept eIF-2 Kinase
Concept Mitogen-Activated Protein Kinase 3
Concept Cyclin-Dependent Kinase Inhibitor p16
Concept Mitogen-Activated Protein Kinase Kinases
Concept Cyclin-Dependent Kinase Inhibitor p21
Concept Protein Kinase C
Concept Receptor-Interacting Protein Serine-Threonine Kinase 2
Concept Receptor Tyrosine Kinase-like Orphan Receptors
Concept Class I Phosphatidylinositol 3-Kinases
Concept MAP Kinase Kinase 6
Concept Cyclin-Dependent Kinase Inhibitor p15
Concept CDC2 Protein Kinase
Concept Protein-Serine-Threonine Kinases
Concept Mitogen-Activated Protein Kinase 1
Concept Calcium-Calmodulin-Dependent Protein Kinases
Concept Phosphatidylinositol 3-Kinases
Concept MAP Kinase Signaling System
Concept JNK Mitogen-Activated Protein Kinases
Concept Extracellular Signal-Regulated MAP Kinases
Concept Cyclin-Dependent Kinase Inhibitor p27
Concept Cyclin-Dependent Kinase 6
Concept fms-Like Tyrosine Kinase 3
Concept Lim Kinases
Concept Protein Kinase Inhibitors
Concept p38 Mitogen-Activated Protein Kinases
Concept Cyclin-Dependent Kinase 2
Concept Cyclin-Dependent Kinase 5
Academic Article Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
Academic Article A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction.
Academic Article Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.
Academic Article Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.
Academic Article Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors.
Academic Article Impact of LIMK1, MMP2 and TNF-a variations for intracranial aneurysm in Japanese population.
Academic Article Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility.
Academic Article Possible involvement of NEDD4 in keloid formation; its critical role in fibroblast proliferation and collagen production.
Academic Article Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
Academic Article A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
Academic Article A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.
Academic Article Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
Academic Article Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA.
Academic Article Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.
Academic Article IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.
Academic Article A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
Academic Article Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53.
Academic Article Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
Academic Article MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells.
Academic Article Association of the RIP2 gene with childhood atopic asthma.
Academic Article ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms.
Academic Article Overexpression of the potential kinase serine/ threonine/tyrosine kinase 1 (STYK 1) in castration-resistant prostate cancer.
Academic Article Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis.
Academic Article Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells.
Academic Article Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
Academic Article Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839).
Academic Article Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).
Academic Article WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.
Academic Article Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family.
Academic Article RASEF is a novel diagnostic biomarker and a therapeutic target for lung cancer.
Academic Article Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
Academic Article Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
Academic Article A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.
Academic Article Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema.
Academic Article Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
Academic Article Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells.
Academic Article A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.
Academic Article Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis.
Academic Article Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma.
Academic Article ESE-3, an Ets family transcription factor, is up-regulated in cellular senescence.
Academic Article A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
Academic Article Gamma-aminobutyric acid (GABA) stimulates pancreatic cancer growth through overexpressing GABAA receptor pi subunit.
Academic Article Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.
Academic Article Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.
Academic Article ANLN plays a critical role in human lung carcinogenesis through the activation of RHOA and by involvement in the phosphoinositide 3-kinase/AKT pathway.
Academic Article Critical roles of T-LAK cell-originated protein kinase in cytokinesis.
Academic Article The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
Academic Article VAV3 mediates resistance to breast cancer endocrine therapy.
Academic Article The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
Academic Article Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
Academic Article Detection of novel cancer-testis antigen-specific T-cell responses in TIL, regional lymph nodes, and PBL in patients with esophageal squamous cell carcinoma.
Academic Article Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.
Academic Article Heterozygous TGFBR2 mutations in Marfan syndrome.
Academic Article Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy.
Academic Article Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN.
Academic Article PDZ-binding kinase/T-LAK cell-originated protein kinase, a putative cancer/testis antigen with an oncogenic activity in breast cancer.
Academic Article TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis.
Academic Article PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents.
Academic Article T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.
Academic Article SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells.
Academic Article Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
Academic Article Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation.
Academic Article Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
Academic Article Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
Academic Article Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations.
Academic Article Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
Academic Article Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
Academic Article Anti-myeloma activity of MELK inhibitor OTS167: effects on drug-resistant myeloma cells and putative myeloma stem cell replenishment of malignant plasma cells.
Academic Article p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1.
Academic Article T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer.
Academic Article Diaminopyridine-based potent and selective mps1 kinase inhibitors binding to an unusual flipped-Peptide conformation.
Academic Article WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck.
Academic Article TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.
Academic Article WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
Academic Article Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells.
Academic Article Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma.
Academic Article MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
Academic Article Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.
Academic Article Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer.
Academic Article High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo.
Academic Article Anti-cancer immunotherapy using cancer-derived multiple epitope-peptides cocktail vaccination clinical studies in patients with refractory/persistent disease of uterine cervical cancer and ovarian cancer [phase 2].

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