Item Type | Name |
Concept
|
Antineoplastic Combined Chemotherapy Protocols
|
Concept
|
Autoimmune Diseases
|
Concept
|
Bone Diseases, Metabolic
|
Concept
|
Cardiovascular Diseases
|
Concept
|
Graft vs Host Disease
|
Concept
|
Coronary Artery Disease
|
Concept
|
Disease
|
Concept
|
Crohn Disease
|
Concept
|
Chronic Disease
|
Concept
|
Disease Susceptibility
|
Concept
|
Drug Therapy, Combination
|
Concept
|
Graft Rejection
|
Concept
|
Hematologic Diseases
|
Concept
|
Muscular Diseases
|
Concept
|
Graves Disease
|
Concept
|
Ovarian Diseases
|
Concept
|
Peripheral Nervous System Diseases
|
Concept
|
Recurrence
|
Concept
|
Respiratory Tract Diseases
|
Concept
|
Stem Cells
|
Concept
|
Tumor Stem Cell Assay
|
Concept
|
Hematopoietic Stem Cell Transplantation
|
Concept
|
Vascular Diseases
|
Concept
|
Peripheral Vascular Diseases
|
Concept
|
Neoplasm Recurrence, Local
|
Concept
|
Disease Progression
|
Concept
|
Embryonic Stem Cells
|
Concept
|
Parkinson Disease
|
Concept
|
Genetic Diseases, X-Linked
|
Concept
|
Mitochondrial Diseases
|
Concept
|
Genetic Diseases, Inborn
|
Concept
|
Chemotherapy, Adjuvant
|
Concept
|
Kidney Diseases, Cystic
|
Concept
|
Lung Diseases, Interstitial
|
Concept
|
Graft vs Leukemia Effect
|
Concept
|
Neurodegenerative Diseases
|
Concept
|
Cord Blood Stem Cell Transplantation
|
Concept
|
Induced Pluripotent Stem Cells
|
Concept
|
Disease Models, Animal
|
Concept
|
Neoplastic Stem Cells
|
Concept
|
Disease-Free Survival
|
Concept
|
Genetic Predisposition to Disease
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Academic Article
|
Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling.
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Academic Article
|
Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice.
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Academic Article
|
Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy.
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Academic Article
|
Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
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Academic Article
|
Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
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Academic Article
|
When good drugs go bad.
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Academic Article
|
A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction.
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Academic Article
|
Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients.
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Academic Article
|
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.
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Academic Article
|
Genetically manipulated human embryonic stem cell-derived dendritic cells with immune regulatory function.
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Academic Article
|
Predicting response to docetaxel neoadjuvant chemotherapy for advanced breast cancers through genome-wide gene expression profiling.
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Academic Article
|
Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.
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Academic Article
|
A model of prediction system for adverse cardiovascular reactions by calcineurin inhibitors among patients with renal transplants using gene-based single-nucleotide polymorphisms.
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Academic Article
|
A genome-wide association study identifies ITGA9 conferring risk of nasopharyngeal carcinoma.
|
Academic Article
|
Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.
|
Academic Article
|
Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.
|
Academic Article
|
Expression of novel molecules, MICAL2-PV (MICAL2 prostate cancer variants), increases with high Gleason score and prostate cancer progression.
|
Academic Article
|
Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.
|
Academic Article
|
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.
|
Academic Article
|
Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients.
|
Academic Article
|
Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count.
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Academic Article
|
Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand.
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Academic Article
|
Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke.
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Academic Article
|
Successful outcomes using combination therapy of interleukin-2 and interferon-alpha for renal cell carcinoma patients with lung metastasis.
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Academic Article
|
PADI4 polymorphism predisposes male smokers to rheumatoid arthritis.
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Academic Article
|
Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.
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Academic Article
|
A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.
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Academic Article
|
Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.
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Academic Article
|
Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.
|
Academic Article
|
A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.
|
Academic Article
|
Common variation in GPC5 is associated with acquired nephrotic syndrome.
|
Academic Article
|
Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility.
|
Academic Article
|
Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy.
|
Academic Article
|
Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population.
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Academic Article
|
SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.
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Academic Article
|
Should CYP2D6 inhibitors be administered in conjunction with tamoxifen?
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Academic Article
|
Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
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Academic Article
|
Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese.
|
Academic Article
|
A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.
|
Academic Article
|
Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis.
|
Academic Article
|
Reproducibility, performance, and clinical utility of a genetic risk prediction model for prostate cancer in Japanese.
|
Academic Article
|
Genome-wide association meta-analysis identifies new endometriosis risk loci.
|
Academic Article
|
Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.
|
Academic Article
|
A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.
|
Academic Article
|
Re: CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the Breast International Group 1-98 trial.
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Academic Article
|
Evaluating genetic risk for prostate cancer among Japanese and Latinos.
|
Academic Article
|
Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
|
Academic Article
|
Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies.
|
Academic Article
|
A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1.
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Academic Article
|
A genome-wide association study identifies three new risk loci for Kawasaki disease.
|
Academic Article
|
Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.
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Academic Article
|
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
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Academic Article
|
Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.
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Academic Article
|
Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.
|
Academic Article
|
Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.
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Academic Article
|
Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.
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Academic Article
|
New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study.
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Academic Article
|
Serum estradiol should be monitored not only during the peri-menopausal period but also the post-menopausal period at the time of aromatase inhibitor administration.
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Academic Article
|
A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
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Academic Article
|
A functional variant in NKX3.1 associated with prostate cancer susceptibility down-regulates NKX3.1 expression.
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Academic Article
|
Meta-analysis identifies common variants associated with body mass index in east Asians.
|
Academic Article
|
A genome-wide association study identifies novel susceptibility genetic variation for thyrotoxic hypokalemic periodic paralysis.
|
Academic Article
|
A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
|
Academic Article
|
Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing.
|
Academic Article
|
A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
|
Academic Article
|
Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians.
|
Academic Article
|
Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese.
|
Academic Article
|
Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk.
|
Academic Article
|
A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese.
|
Academic Article
|
Prostate cancer genomics, biology, and risk assessment through genome-wide association studies.
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Academic Article
|
A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
|
Academic Article
|
A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
|
Academic Article
|
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
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Academic Article
|
Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.
|
Academic Article
|
Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash.
|
Academic Article
|
Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA.
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Academic Article
|
IRX4 at 5p15 suppresses prostate cancer growth through the interaction with vitamin D receptor, conferring prostate cancer susceptibility.
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Academic Article
|
Novel deletion mutations of OPTN in amyotrophic lateral sclerosis in Japanese.
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Academic Article
|
Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.
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Academic Article
|
A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations.
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Academic Article
|
Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
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Academic Article
|
Functional variants in NFKBIE and RTKN2 involved in activation of the NF-?B pathway are associated with rheumatoid arthritis in Japanese.
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Academic Article
|
Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.
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Academic Article
|
SLC22A4 polymorphism and rheumatoid arthritis susceptibility: a replication study in a Japanese population and a metaanalysis.
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Academic Article
|
Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression.
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Academic Article
|
Genome-wide association study of hematological and biochemical traits in a Japanese population.
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Academic Article
|
A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
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Academic Article
|
A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility.
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Academic Article
|
Replication study for the association between four Loci identified by a genome-wide association study on European American subjects with type 1 diabetes and susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes.
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Academic Article
|
Genome-wide association study of pancreatic cancer in Japanese population.
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Academic Article
|
IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.
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Academic Article
|
Combined immunotherapy with low-dose IL-2 plus IFN-alpha for metastatic renal cell carcinoma: survival benefit for selected patients with lung metastasis and serum sodium level.
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Academic Article
|
Interstitial lung disease in gefitinib-treated Japanese patients with non-small-cell lung cancer: genome-wide analysis of genetic data.
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Academic Article
|
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.
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Academic Article
|
Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.
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Academic Article
|
ORAI1 genetic polymorphisms associated with the susceptibility of atopic dermatitis in Japanese and Taiwanese populations.
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Academic Article
|
Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy.
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Academic Article
|
Lack of association between variations of PDE4D and ischemic stroke in the Japanese population.
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Academic Article
|
A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.
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Academic Article
|
Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1.
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Academic Article
|
Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population.
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Academic Article
|
Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population.
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Academic Article
|
Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis.
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Academic Article
|
A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
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Academic Article
|
HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.
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Academic Article
|
A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
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Academic Article
|
A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population.
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Academic Article
|
A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
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Academic Article
|
Association of allelic loss at 8p22 with poor prognosis among breast cancer cases treated with high-dose adjuvant chemotherapy.
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Academic Article
|
Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers.
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Academic Article
|
Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy.
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Academic Article
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Identification of 46 novel SNPs in the 130-kb region containing a myocardial infarction susceptibility gene on chromosomal band 6p21.
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Academic Article
|
Genome-wide gene-expression profiles of breast-cancer cells purified with laser microbeam microdissection: identification of genes associated with progression and metastasis.
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Academic Article
|
Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction.
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Academic Article
|
[A phase I study of combination-therapy with gemcitabine and epitope peptides derived from human vascular endothelial growth factor receptor for unresectable or recurrent pancreas cancer].
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Academic Article
|
Genes associated with liver metastasis of colon cancer, identified by genome-wide cDNA microarray.
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Academic Article
|
Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction.
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Academic Article
|
Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.
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Academic Article
|
A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer.
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Academic Article
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Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.
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Academic Article
|
Molecular features of hormone-refractory prostate cancer cells by genome-wide gene expression profiles.
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Academic Article
|
Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
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Academic Article
|
A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
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Academic Article
|
Genome-wide screening by cDNA microarray of genes associated with matrix mineralization by human mesenchymal stem cells in vitro.
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Academic Article
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Association study of 71 European Crohn's disease susceptibility loci in a Japanese population.
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Academic Article
|
Serum REG4 level is a predictive biomarker for the response to preoperative chemoradiotherapy in patients with pancreatic cancer.
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Academic Article
|
Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
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Academic Article
|
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
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Academic Article
|
Common variants in CASP3 confer susceptibility to Kawasaki disease.
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Academic Article
|
The textile plot: a new linkage disequilibrium display of multiple-single nucleotide polymorphism genotype data.
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Academic Article
|
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.
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Academic Article
|
Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and PINs.
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Academic Article
|
Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13.
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Academic Article
|
Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus.
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Academic Article
|
Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b.
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Academic Article
|
INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.
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Academic Article
|
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
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Academic Article
|
Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese.
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Academic Article
|
Stanniocalcin 2 overexpression in castration-resistant prostate cancer and aggressive prostate cancer.
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Academic Article
|
A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese.
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Academic Article
|
Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
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Academic Article
|
MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells.
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Academic Article
|
Impact of PSCA variation on gastric ulcer susceptibility.
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Academic Article
|
A genomewide linkage analysis of Kawasaki disease: evidence for linkage to chromosome 12.
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Academic Article
|
Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma.
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Academic Article
|
ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms.
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Academic Article
|
Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome.
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Academic Article
|
Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
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Academic Article
|
Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus.
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Academic Article
|
HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy.
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Academic Article
|
Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin.
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Academic Article
|
A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.
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Academic Article
|
Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia.
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Academic Article
|
Identification of a functional variant in SPLUNC1 associated with nasopharyngeal carcinoma susceptibility among Malaysian Chinese.
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Academic Article
|
Important and critical scientific aspects in pharmacogenomics analysis: lessons from controversial results of tamoxifen and CYP2D6 studies.
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Academic Article
|
High-density genotyping study identifies four new susceptibility loci for atopic dermatitis.
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Academic Article
|
Identification of CAG repeat-containing genes expressed in human brain as candidate genes for autosomal dominant spinocerebellar ataxias and other neurodegenerative diseases.
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Academic Article
|
Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences.
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Academic Article
|
A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis.
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Academic Article
|
Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.
|
Academic Article
|
Identification of sequence polymorphisms in CALM2 and analysis of association with hip osteoarthritis in a Japanese population.
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Academic Article
|
Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.
|
Academic Article
|
The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
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Academic Article
|
Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C.
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Academic Article
|
Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.
|
Academic Article
|
An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes.
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Academic Article
|
Seven new loci associated with age-related macular degeneration.
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Academic Article
|
Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
|
Academic Article
|
Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease.
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Academic Article
|
An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis.
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Academic Article
|
Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma.
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Academic Article
|
Validation study of the prediction system for clinical response of M-VAC neoadjuvant chemotherapy.
|
Academic Article
|
Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
|
Academic Article
|
CD40 ligand gene and Kawasaki disease.
|
Academic Article
|
Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease.
|
Academic Article
|
Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.
|
Academic Article
|
Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5.
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Academic Article
|
Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis.
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Academic Article
|
Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma.
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Academic Article
|
A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction.
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Academic Article
|
[SNP collection, pharmacogenomics, and the future of drug therapy].
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Academic Article
|
Combinational effect of genes for the renin-angiotensin system in conferring susceptibility to diabetic nephropathy.
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Academic Article
|
Colorectal cancer metastasis to the thyroid.
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Academic Article
|
A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese.
|
Academic Article
|
Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population.
|
Academic Article
|
Microarray analysis of gene-expression profiles in diffuse large B-cell lymphoma: identification of genes related to disease progression.
|
Academic Article
|
Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention.
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Academic Article
|
Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS.
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Academic Article
|
SNPs in BRAP associated with risk of myocardial infarction in Asian populations.
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Academic Article
|
Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema.
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Academic Article
|
[Phase I study of combination therapy with peptide vaccine and anti-cancer drug for colorectal cancer].
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Academic Article
|
Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.
|
Academic Article
|
Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis.
|
Academic Article
|
A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.
|
Academic Article
|
Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes.
|
Academic Article
|
A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease.
|
Academic Article
|
Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.
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Academic Article
|
A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.
|
Academic Article
|
Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.
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Academic Article
|
Plakophilin 3 oncogene as prognostic marker and therapeutic target for lung cancer.
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Academic Article
|
Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population.
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Academic Article
|
Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.
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Academic Article
|
Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.
|
Academic Article
|
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.
|
Academic Article
|
High-resolution SNP map of ASPN, a susceptibility gene for osteoarthritis.
|
Academic Article
|
[S-1/CDDP combined neoadjuvant chemotherapy and surgical resection for advanced gastric cancer. Analysis of 12 patients with lymph node metastasis in Saitama Red Cross Hospital].
|
Academic Article
|
Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
|
Academic Article
|
Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.
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Academic Article
|
Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population.
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Academic Article
|
Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.
|
Academic Article
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HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study.
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[BioBank Japan project].
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The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort.
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A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population.
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Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles.
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Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappaB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure.
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Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.
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HLA-A SNPs and amino acid variants are associated with nasopharyngeal carcinoma in Malaysian Chinese.
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A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese.
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A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
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A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells.
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Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.
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A functional polymorphism in MMP-9 is associated with childhood atopic asthma.
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A single nucleotide polymorphism in KCNQ1 is associated with susceptibility to diabetic nephropathy in japanese subjects with type 2 diabetes.
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Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population.
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A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.
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Serial analysis of gene expression in progressing and regressing mouse tumors implicates the involvement of RANTES and TARC in antitumor immune responses.
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Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis.
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A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5' flanking region of SMYD3 is a risk factor for human cancers.
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FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.
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A phase ?I study of five peptides combination with oxaliplatin-based chemotherapy as a first-line therapy for advanced colorectal cancer (FXV study).
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Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor.
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Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome.
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Quantitative characterization of T-cell repertoire in allogeneic hematopoietic stem cell transplant recipients.
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Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy.
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Identification of CDCA1-derived long peptides bearing both CD4+ and CD8+ T-cell epitopes: CDCA1-specific CD4+ T-cell immunity in cancer patients.
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Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.
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Germline PARP4 mutations in patients with primary thyroid and breast cancers.
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Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway.
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Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens.
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Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population.
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Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer.
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Characterization of T-cell Receptor Repertoire in Inflamed Tissues of Patients with Crohn's Disease Through Deep Sequencing.
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Recurrence in regional pulmonary lymph nodes after surgery for isolated pulmonary metastasis from hepatocellular carcinoma.
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Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
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Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors.
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Clonal expansion of antitumor T?cells in breast cancer correlates with response to neoadjuvant chemotherapy.
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Deep-sequencing of the T-cell receptor repertoire in patients with haplo-cord and matched-donor transplants.
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Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.
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Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.
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Anti-myeloma activity of MELK inhibitor OTS167: effects on drug-resistant myeloma cells and putative myeloma stem cell replenishment of malignant plasma cells.
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Pharmacogenomics and drug toxicity.
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Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy.
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Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study.
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Cancer Precision Medicine: From Cancer Screening to Drug Selection and Personalized Immunotherapy.
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T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer.
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TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.
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Risk prediction models for mortality in patients with cardiovascular disease: The BioBank Japan project.
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Predicting response of bladder cancers to gemcitabine and carboplatin neoadjuvant chemotherapy through genome-wide gene expression profiling.
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Identification of immunogenic LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes and eliciting CD4+ T-cell immunity in patients with malignant disease.
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Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection.
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Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases.
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Overview of BioBank Japan follow-up data in 32 diseases.
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Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
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Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort.
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Multiple therapeutic peptide vaccines for patients with advanced gastric cancer.
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SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+?breast cancer: genome-wide association studies of the estrone pathway.
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Case of malignant melanoma that developed the ability to secrete granulocyte colony-stimulating factor.
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Toxic epidermal necrolysis in a child 6 months post-hematopoietic stem cell transplantation.
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[A case of inoperable gastric small cell carcinoma effectively treated by chemotherapy and radiotherapy].
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Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophageal cancer patients.
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Development of small molecular compounds targeting cancer stem cells.
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A prospective study to examine the accuracies and efficacies of prediction systems for response to neoadjuvant chemotherapy for muscle invasive bladder cancer.
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The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
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Immunotherapy with cancer peptides in combination with intravesical bacillus Calmette-Guerin for patients with non-muscle invasive bladder cancer.
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Critical roles of protein methyltransferases and demethylases in the regulation of embryonic stem cell fate.
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GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.
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Immunoglobulin profiling identifies unique signatures in patients with Kawasaki disease during intravenous immunoglobulin treatment.
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The era of immunogenomics/immunopharmacogenomics.
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Free-floating cancer cells in lymph node sinuses of hilar lymph node-positive patients with non-small cell lung cancer.
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Breast cancer: The translation of big genomic data to cancer precision medicine.
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Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21.
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MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
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Tamoxifen Metabolism and Breast Cancer Recurrence: A Question Unanswered by CYPTAM.
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Importance of gastric cancer for the diagnosis and surveillance of Japanese Lynch syndrome patients.
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Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.
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Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population.
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Dose escalation prophylactic donor lymphocyte infusion after T-cell depleted matched related donor allogeneic hematopoietic cell transplantation is feasible and results in higher donor chimerism, faster immune re-constitution, and prolonged progression-free survival.
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WHSC1 monomethylates histone H1 and induces stem-cell like features in squamous cell carcinoma of the head and neck.
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Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.
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Phase II Adjuvant Cancer-specific Vaccine Therapy for Esophageal Cancer Patients Curatively Resected After Preoperative Therapy With Pathologically Positive Nodes; Possible Significance of Tumor Immune Microenvironment in its Clinical Effects.
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Anti-cancer immunotherapy using cancer-derived multiple epitope-peptides cocktail vaccination clinical studies in patients with refractory/persistent disease of uterine cervical cancer and ovarian cancer [phase 2].
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Genome-wide association study of epilepsy in a Japanese population identified an associated region at chromosome 12q24.
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Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome.
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A cross-population atlas of genetic associations for 220 human phenotypes.
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Tumor-informed or tumor-agnostic circulating tumor DNA as a biomarker for risk of recurrence in resected colorectal cancer patients.
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