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One or more keywords matched the following properties of Awad, Issam
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overview Awad was recruited in 2010 to lead the Neurovascular Surgery Program at the University of Chicago Medicine, and is currently tenured in the Biological Sciences Division. He is the John Harper Seeley Professor of Neurological Sciences and Professor of Neurological Surgery, Neurology, the Grossman Institute of Neuroscience, Quantitative Biology and Human Behavior, and the (PhD granting) Committee on Neurobiology. He is a Senior Faculty Scholar at the Bucksbaum Institute for Clinical Excellence and directs the Safadi Program of Excellence in Clinical and Translational Neurosciences. Dr Awad is active in numerous professional and learned societies. He has served on the Executive Committee of the American Stroke Association, and on the Board of Governors of the American College of Surgeons. He was the Chairman of the Joint Cerebrovascular Section of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, he has directed the Annual Course on Research Update in Neuroscience for Neurosurgeons, and he served as the 51st President of the Congress of Neurological Surgeons. Dr Awad is the Founding past-President of the World Association of Lebanese Neurosurgeons, and the Founding Chairman of Scientific Advisory Board of the patient advocacy group Angioma Alliance. Dr Awad has authored over 350 scientific papers and book chapters, and edited twelve books dealing with cerebrovascular surgery and other aspects of neurological surgery. He has presented over 500 papers and lectures at major meetings and symposia, has been a visiting professor at numerous institutions in the United States and abroad, was recognized among America’s Best Doctors, Best Teachers, and is the recipient of the Bucy Award for Excellence in Neurosurgical Education, the Arnold Award for Mentoring at Pritzker School of Medicine, and numerous other honors. Dr Awad has made numerous scientific contributions including the characterization of subcortical ischemic lesions in the aged, advances in the understanding of the natural history and biologic behavior of vascular malformations of the brain, numerous technical advances in neurovascular and epilepsy surgery, and is a recognized expert in the treatment of neurovascular disease, hemorrhagic stroke and neurosurgical critical care. His research has been cited by other researchers more than 79,000 times (H-index 91). Current research focuses on molecular mechanisms, biomarkers and therapeutic targets in cavernous angiomas (cerebral vascular malformations), the pathobiology of brain hemorrhage, and minimally invasive techniques for treating hemorrhagic stroke. Dr. Awad's research has been funded continuously from the National Institutes of Health since 1998, including a prestigious midcareer development grant in patient-oriented research (2000-2005), and current active R01, P01 and U01 funding through 2025. From 2016 to 2020, he served on the United States National Advisory Council for Neurological Disorders and Stroke. In 2019, he was elected to the Association of American Physicians. www.issamawad.com www.uchicagomedicine.org/ccm www.uchicagomedicine.org/hht http://safadiprogram.uchicago.edu
One or more keywords matched the following items that are connected to Awad, Issam
Item TypeName
Concept Telangiectasia, Hereditary Hemorrhagic
Concept Stroke
Academic Article Misdiagnosis of symptomatic cerebral aneurysm. Prevalence and correlation with outcome at four institutions.
Academic Article Cerebral vascular malformations adjacent to sensorimotor and visual cortex. Functional magnetic resonance imaging studies before and after therapeutic intervention.
Academic Article A quality-of-life instrument for young hemorrhagic stroke patients.
Academic Article Multilocus linkage identifies two new loci for a mendelian form of stroke, cerebral cavernous malformation, at 7p15-13 and 3q25.2-27.
Academic Article Recommendations for the management of patients with unruptured intracranial aneurysms: A Statement for healthcare professionals from the Stroke Council of the American Heart Association.
Academic Article Endothelial cell culture from human cerebral cavernous malformations.
Academic Article Hemorrhagic lesion at the tentorial incisura in a patient with facial nevus.
Academic Article Stereotactic computed tomographic-guided aspiration and thrombolysis of intracerebral hematoma : protocol and preliminary experience.
Academic Article AHA Scientific Statement: Recommendations for the management of intracranial arteriovenous malformations: a statement for healthcare professionals from a special writing group of the Stroke Council, American Stroke Association.
Academic Article Biallelic somatic and germ line CCM1 truncating mutations in a cerebral cavernous malformation lesion.
Academic Article How frequently should we follow small asymptomatic intracranial aneurysms?
Academic Article Hemorrhage from cavernous malformations of the brain: definition and reporting standards. Angioma Alliance Scientific Advisory Board.
Academic Article Advances in open neurovascular surgery 2007.
Academic Article Ipsilateral leg weakness associated with carotid stenosis.
Academic Article Genomics of human intracranial aneurysm wall.
Academic Article Prostacyclin in experimental ischemic models.
Academic Article Resolution of intraventricular hemorrhage varies by ventricular region and dose of intraventricular thrombolytic: the Clot Lysis: Evaluating Accelerated Resolution of IVH (CLEAR IVH) program.
Academic Article Periventricular lesions on MRI. Facts and theories.
Academic Article Treatment of acute focal cerebral ischemia with prostacyclin.
Academic Article Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease.
Academic Article Clinical vasospasm after subarachnoid hemorrhage: response to hypervolemic hemodilution and arterial hypertension.
Academic Article Focal parenchymal lesions in transient ischemic attacks: correlation of computed tomography and magnetic resonance imaging.
Academic Article Incidental subcortical lesions identified on magnetic resonance imaging in the elderly. I. Correlation with age and cerebrovascular risk factors.
Academic Article Incidental subcortical lesions identified on magnetic resonance imaging in the elderly. II. Postmortem pathological correlations.
Academic Article Intravenous digital subtraction angiography: an index of collateral cerebral blood flow in internal carotid artery occlusion.
Academic Article Intracranial hypertension after resection of cerebral arteriovenous malformations. Predisposing factors and management strategy.
Academic Article Sensitivity of magnetic resonance diffusion-weighted imaging and regional relationship between the apparent diffusion coefficient and cerebral blood flow in rat focal cerebral ischemia.
Academic Article Reporting terminology for brain arteriovenous malformation clinical and radiographic features for use in clinical trials.
Academic Article Coronary risk evaluation in patients with transient ischemic attack and ischemic stroke: a scientific statement for healthcare professionals from the Stroke Council and the Council on Clinical Cardiology of the American Heart Association/American Stroke Association.
Academic Article Pathogenesis of subcortical hyperintense lesions on magnetic resonance imaging of the brain. Observations in patients undergoing controlled therapeutic internal carotid artery occlusion.
Academic Article Immune response in human cerebral cavernous malformations.
Academic Article Biology of vascular malformations of the brain.
Academic Article Patch angioplasty in carotid endarterectomy. Advantages, concerns, and controversies.
Academic Article Low-dose recombinant tissue-type plasminogen activator enhances clot resolution in brain hemorrhage: the intraventricular hemorrhage thrombolysis trial.
Academic Article Intensive care management of acute hemorrhagic leukoencephalitis with favorable neurologic outcome.
Academic Article Ischemic stroke and intracranial multifocal cerebral arteriopathy in Williams syndrome.
Academic Article Exceptional multiplicity of cerebral arteriovenous malformations associated with hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome).
Academic Article Magnetic resonance diffusion-weighted imaging: sensitivity and apparent diffusion constant in stroke.
Academic Article Recommendations for the management of intracranial arteriovenous malformations: a statement for healthcare professionals from a special writing group of the Stroke Council, American Stroke Association.
Academic Article MR of hereditary hemorrhagic telangiectasia: prevalence and spectrum of cerebrovascular malformations.
Academic Article Protocols and critical pathways for stroke care.
Academic Article [Etiologic spectrum of intracerebral hemorrhage in young patients].
Academic Article Advances in the genetics of cerebrovascular disease and stroke.
Academic Article [Genetic factors related to intracranial arteriovenous malformations].
Academic Article The Modified Graeb Score: an enhanced tool for intraventricular hemorrhage measurement and prediction of functional outcome.
Academic Article Primary intracerebral hemorrhage and subarachnoid hemorrhage.
Academic Article Coronary risk evaluation in patients with transient ischemic attack and ischemic stroke: a scientific statement for healthcare professionals from the Stroke Council and the Council on Clinical Cardiology of the American Heart Association/American Stroke Association.
Academic Article What genes can teach us about human cerebrovascular malformations.
Academic Article Update on current registries and trials of carotid artery angioplasty and stent placement.
Academic Article Minimally invasive surgery plus recombinant tissue-type plasminogen activator for intracerebral hemorrhage evacuation decreases perihematomal edema.
Academic Article Hemorrhagic stroke: introduction.
Academic Article Surgical trials in intracerebral hemorrhage.
Academic Article Recommendations for the management of patients with unruptured intracranial aneurysms: A statement for healthcare professionals from the Stroke Council of the American Heart Association.
Academic Article Guidelines for the prevention of stroke in women: a statement for healthcare professionals from the American Heart Association/American Stroke Association.
Academic Article A multicenter, randomized, double-blinded, placebo-controlled phase III study of Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III).
Academic Article Dynamic permeability and quantitative susceptibility: related imaging biomarkers in cerebral cavernous malformations.
Academic Article Accuracy of the ABC/2 Score for Intracerebral Hemorrhage: Systematic Review and Analysis of MISTIE, CLEAR-IVH, and CLEAR III.
Academic Article RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations.
Academic Article Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III trial.
Academic Article Symptomatic Hemorrhagic Complications in Clot Lysis: Evaluation of Accelerated Resolution of Intraventricular Hemorrhage Phase III Clinical Trial (CLEAR III): A Posthoc Root-Cause Analysis.
Academic Article Plasma Biomarkers of Inflammation Reflect Seizures and Hemorrhagic Activity of Cerebral Cavernous Malformations.
Academic Article Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.
Academic Article A randomized 500-subject open-label phase 3 clinical trial of minimally invasive surgery plus alteplase in intracerebral hemorrhage evacuation (MISTIE III).
Academic Article A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease.
Academic Article Primary intraventricular hemorrhage outcomes in the CLEAR III trial.
Academic Article Impact of Intracranial Pressure Monitor-Guided Therapy on Neurologic Outcome After Spontaneous Nontraumatic Intracranial Hemorrhage.
Academic Article Temporal Evolution and Outcomes of Non-Traumatic Intracerebral Hemorrhage in Hospitalized Patients.
Academic Article Post-Trial Enhanced Deployment and Technical Performance with the MISTIE Procedure per Lessons Learned.
Academic Article Post-Stroke Depression in Patients with Large Spontaneous Intracerebral Hemorrhage.
Academic Article COVID-19 in a Hemorrhagic Neurovascular Disease, Cerebral Cavernous Malformation.
Academic Article Baseline Characteristics of Patients With Cavernous Angiomas With Symptomatic Hemorrhage in Multisite Trial Readiness Project.
Academic Article Intraventricular Hemorrhage Expansion in the CLEAR III Trial: A Post Hoc Exploratory Analysis.
Academic Article Association of Intraventricular Fibrinolysis With Clinical Outcomes in Intracerebral Hemorrhage: An Individual Participant Data Meta-Analysis.
Academic Article Circulating Plasma miRNA Homologs in Mice and Humans Reflect Familial Cerebral Cavernous Malformation Disease.
Academic Article One-Year Outcome Trajectories and Factors Associated with Functional Recovery Among Survivors of Intracerebral and Intraventricular Hemorrhage With Initial Severe Disability.
Academic Article Evidence-based interconversion of the Glasgow Outcome and modified Rankin scales: pitfalls and best practices.
Academic Article Multidisciplinary coordinated care of hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease).
Grant Rock Inhibition as Therapy for Cerebral Cavernous Malformation
Grant IMMUNE RESPONSE IN HUMAN CEREBRAL CAVERNOUS MALFORMATIONS
Grant PHENOTYPE-GENOTYPE IN GEREBRAL VASCULAR MALFORMATIOINS
Grant Genesis and Progression of Cerebral Cavernous Malformations
Grant Development of BA-1049 for treatment of cerebral cavernous malformation
Grant BIOMARKERS OF BRAIN PERMEABILITY IN HUMAN CEREBRAL CAVERNOUS MALFORMATIONS
Academic Article Impact of socioeconomics and race on clinical follow-up and trial enrollment and adherence in cerebral cavernous malformation.
Academic Article Underlying intracranial atherosclerotic disease is associated with worse outcomes in acute large vessel occlusion undergoing endovascular thrombectomy.
Academic Article mTORC1 Inhibitor Rapamycin Inhibits Growth of Cerebral Cavernous Malformation in Adult Mice.
Academic Article Cerebral small vessel disease modifies outcomes after minimally invasive surgery for intracerebral haemorrhage.
Academic Article Trial Readiness of Cavernous Malformations With Symptomatic Hemorrhage, Part II: Biomarkers and Trial Modeling.
Academic Article Trial Readiness of Cavernous Malformations With Symptomatic Hemorrhage, Part I: Event Rates and Clinical Outcome.
Academic Article Association Between Hematoma Volume and Risk of Subsequent Ischemic Stroke: A MISTIE III and ATACH-2 Analysis.
Academic Article Pathologic Features of Brain Hemorrhage After Radiation Treatment: Case Series with Somatic Mutation Analysis.
Search Criteria
  • Hemorrhagic
  • stroke