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overview Daniel J. Haraf, MD, is an expert in the treatment of lung, esophageal and head and neck cancer. He was instrumental in pioneering the use of intensity modulated radiation therapy (IMRT)--a highly precise form of three-dimensional conformal radiotherapy. IMRT uses computers to accurately plan and deliver radiation with the fewest possible side effects for patients. He has become a nationally recognized leader in the treatment of head and neck cancer (HNC). Dr. Haraf has been a major force in developing a program using chemotherapy together with IMRT in the treatment of patients with HNC--reducing or eliminating the need for extensive, debilitating, or mutilating surgery. This program has a long track record curing cancer with preservation of normal organ function as documented in the medical literature. Dr. Haraf is proud that we can actually discuss the expected results with our patients based on detailed analyses of our own treatment program. Dr. Haraf has also pioneered re-irradiation for patients with recurrent cancer of the head and neck. People with recurrent cancer after radiation often have limited treatment options and little chance of cure. Most radiation oncologists will not consider offering a second round of radiation treatment. Dr. Haraf has found that re-irradiation is possible and offers these people their only chance of cure. He is active in developing new methods of radiation delivery for patients with lung and esophageal cancer. Cancers in the chest can move while people breathe during treatment. We now have the technology to time the delivery of radiation to a specific part of respiration. The result is greater accuracy in treating the cancer while limiting the amount of normal lung tissue exposed to radiation.

One or more keywords matched the following items that are connected to Haraf, Daniel J.

Item TypeName
Concept Head and Neck Neoplasms
Academic Article Re-irradiation with concomitant chemotherapy of unresectable recurrent head and neck cancer: a potentially curable disease.
Academic Article Continuous infusion paclitaxel, 5-fluorouracil, and hydroxyurea with concomitant radiotherapy in patients with advanced or recurrent head and neck cancer.
Academic Article Favorable long-term survival following induction chemotherapy with cisplatin, fluorouracil, and leucovorin and concomitant chemoradiotherapy for locally advanced head and neck cancer.
Academic Article Cisplatin, fluorouracil, and leucovorin augmented by interferon alfa-2b in head and neck cancer: a clinical and pharmacologic analysis.
Academic Article Pharmacodynamics of fluorouracil-based induction chemotherapy in advanced head and neck cancer.
Academic Article The Performance Status Scale for Head and Neck Cancer Patients and the Functional Assessment of Cancer Therapy-Head and Neck Scale. A study of utility and validity.
Academic Article Perspectives on combination chemotherapy with concomitant radiotherapy for poor-prognosis head and neck cancer.
Academic Article Radiation therapy with concomitant hydroxyurea and fluorouracil in stage II and III head and neck cancer.
Academic Article Phase I study of concomitant chemoradiotherapy with paclitaxel, fluorouracil, and hydroxyurea with granulocyte colony-stimulating factor support for patients with poor-prognosis cancer of the head and neck.
Academic Article Induction chemotherapy followed by concurrent chemoradiation for advanced head and neck cancer: improved disease control and survival.
Academic Article Performance and quality of life outcome in patients completing concomitant chemoradiotherapy protocols for head and neck cancer.
Academic Article Osteoradionecrosis of the jaws as a risk factor in radiotherapy: a report of an eight-year retrospective review.
Academic Article Neoadjuvant PFL augmented by methotrexate and piritrexim followed by concomitant chemoradiotherapy for advanced head and neck cancer: a feasible and active approach.
Academic Article Concomitant chemoradiotherapy as primary therapy for locoregionally advanced head and neck cancer.
Academic Article A phase I-II study of concomitant chemoradiotherapy with paclitaxel (one-hour infusion), 5-fluorouracil and hydroxyurea with granulocyte colony stimulating factor support for patients with poor prognosis head and neck cancer.
Academic Article Concomitant chemoradiotherapy with cisplatin, 5-fluorouracil and hydroxyurea in poor-prognosis head and neck cancer.
Academic Article Quality of life and performance in advanced head and neck cancer patients on concomitant chemoradiotherapy: a prospective examination.
Academic Article Phase I study of eniluracil, a dihydropyrimidine dehydrogenase inactivator, and oral 5-fluorouracil with radiation therapy in patients with recurrent or advanced head and neck cancer.
Academic Article Volumetric visualization of head and neck CT data for treatment planning.
Academic Article Oral 5-FU alternatives for the treatment of head and neck cancer.
Academic Article How Do head and neck cancer patients prioritize treatment outcomes before initiating treatment?
Academic Article Paclitaxel, 5-fluorouracil, hydroxyurea, and concomitant radiation therapy for poor-prognosis head and neck cancer.
Academic Article 5-Fluorouracil, leucovorin, hydroxyurea, and escalating doses of continuous-infusion cisplatin with concomitant radiotherapy: a clinical and pharmacologic study.
Academic Article Initial clinical experience with a video-based patient positioning system.
Academic Article The role of cervical lymphadenectomy after aggressive concomitant chemoradiotherapy: the feasibility of selective neck dissection.
Academic Article Hydroxyurea with concomitant radiotherapy for locally advanced head and neck cancer.
Academic Article The use of concurrent chemotherapy and radiotherapy for locoregionally advanced head and neck cancer.
Academic Article Weekly carboplatin and paclitaxel followed by concomitant paclitaxel, fluorouracil, and hydroxyurea chemoradiotherapy: curative and organ-preserving therapy for advanced head and neck cancer.
Academic Article Survival and analysis of failure following hydroxyurea, 5-fluorouracil and concomitant radiation therapy in poor prognosis head and neck cancer.
Academic Article Intensive concurrent chemoradiotherapy for head and neck cancer with 5-Fluorouracil- and hydroxyurea-based regimens: reversing a pattern of failure.
Academic Article Reirradiation: a potentially curative approach to locally or regionally recurrent head and neck cancer.
Academic Article Reirradiation of recurrent and second primary head and neck malignancies: a comprehensive review.
Academic Article Induction chemotherapy followed by concomitant TFHX chemoradiotherapy with reduced dose radiation in advanced head and neck cancer.
Academic Article Concurrent chemoradiotherapy for N2 or N3 squamous cell carcinoma of the head and neck from an occult primary.
Academic Article Swallowing dysfunction--preventative and rehabilitation strategies in patients with head-and-neck cancers treated with surgery, radiotherapy, and chemotherapy: a critical review.
Academic Article Competing causes of death and second primary tumors in patients with locoregionally advanced head and neck cancer treated with chemoradiotherapy.
Academic Article Neck dissection in the combined-modality therapy of patients with locoregionally advanced head and neck cancer.
Academic Article Is patient travel distance associated with survival on phase II clinical trials in oncology?
Academic Article Twice-daily reirradiation for recurrent and second primary head-and-neck cancer with gemcitabine, paclitaxel, and 5-fluorouracil chemotherapy.
Academic Article Phase I study of concomitant chemoradiotherapy with paclitaxel, fluorouracil, gemcitabine, and twice-daily radiation in patients with poor-prognosis cancer of the head and neck.
Academic Article Multicenter randomized Phase II study of paclitaxel (1-hour infusion), fluorouracil, hydroxyurea, and concomitant twice daily radiation with or without erythropoietin for advanced head and neck cancer.
Academic Article Long-term outcome of concurrent chemotherapy and reirradiation for recurrent and second primary head-and-neck squamous cell carcinoma.
Academic Article Intensity-modulated radiation therapy in advanced head and neck patients treated with intensive chemoradiotherapy: preliminary experience and future directions.
Academic Article Phase I trial of tirapazamine, cisplatin, and concurrent accelerated boost reirradiation in patients with recurrent head and neck cancer.
Academic Article Patterns of failure, prognostic factors and survival in locoregionally advanced head and neck cancer treated with concomitant chemoradiotherapy: a 9-year, 337-patient, multi-institutional experience.
Academic Article A phase I trial of docetaxel based induction and concomitant chemotherapy in patients with locally advanced head and neck cancer.
Academic Article Aspiration in chemoradiated patients with head and neck cancer.
Academic Article Phase I study of bevacizumab added to fluorouracil- and hydroxyurea-based concomitant chemoradiotherapy for poor-prognosis head and neck cancer.
Academic Article Phase I study of concomitant chemoradiotherapy with irinotecan, 5-FU, and hydroxyurea for patients with advanced and/or recurrent head and neck cancer.
Academic Article Characteristics associated with swallowing changes after concurrent chemotherapy and radiotherapy in patients with head and neck cancer.
Academic Article Pilot study examining tumor expression of RAD51 and clinical outcomes in human head cancers.
Academic Article High survival and organ function rates after primary chemoradiotherapy for intermediate-stage squamous cell carcinoma of the head and neck treated in a multicenter phase II trial.
Academic Article Epidermal growth factor receptor inhibitor gefitinib added to chemoradiotherapy in locally advanced head and neck cancer.
Academic Article Factors associated with long-term speech and swallowing outcomes after chemoradiotherapy for locoregionally advanced head and neck cancer.
Academic Article Prior chemoradiotherapy adversely impacts outcomes of recurrent and second primary head and neck cancer treated with concurrent chemotherapy and reirradiation.
Academic Article A randomized phase II study of 5-fluorouracil, hydroxyurea, and twice-daily radiotherapy compared with bevacizumab plus 5-fluorouracil, hydroxyurea, and twice-daily radiotherapy for intermediate-stage and T4N0-1 head and neck cancers.
Academic Article Phase II trial of pemetrexed-based induction chemotherapy followed by concomitant chemoradiotherapy in previously irradiated patients with squamous cell carcinoma of the head and neck.
Academic Article Free-flap reconstruction in the doubly irradiated patient population.
Academic Article Swallowing function following multispecialty organ preservation treatment of advanced head and neck-cancer.
Academic Article Intensified concomitant chemoradiotherapy with and without filgrastim for poor-prognosis head and neck cancer.
Academic Article Induction chemotherapy followed by concomitant chemoradiotherapy for advanced head and neck cancer: impact on the natural history of the disease.
Academic Article Predictors of competing mortality in advanced head and neck cancer.
Academic Article Planned post-chemoradiation neck dissection: significance of radiation dose.
Academic Article Occurrence of p53 gene deletions and human papilloma virus infection in human head and neck cancer.
Academic Article The role of paclitaxel in the treatment of head and neck cancer.
Academic Article Hydroxyurea with continuous infusion paclitaxel, 5-fluorouracil, and concomitant radiotherapy for poor-prognosis head and neck cancer.
Academic Article Surgical management of the head and neck cancer patient following concomitant multimodality therapy.
Academic Article Radiation therapy in head and neck cancer: indications and limitations.
Academic Article Neck response to chemoradiotherapy: complete radiographic response correlates with pathologic complete response in locoregionally advanced head and neck cancer.
Academic Article Human papilloma virus and p53 in head and neck cancer: clinical correlates and survival.
Academic Article Swallowing function in patients with head and neck cancer prior to treatment.
Academic Article Concomitant infusional paclitaxel and fluorouracil, oral hydroxyurea, and hyperfractionated radiation for locally advanced squamous head and neck cancer.
Academic Article Site of disease and treatment protocol as correlates of swallowing function in patients with head and neck cancer treated with chemoradiation.
Academic Article Induction chemotherapy and concurrent chemoradiotherapy for locoregionally advanced head and neck cancer: a multi-institutional phase II trial investigating three radiotherapy dose levels.
Academic Article Adjuvant chemotherapy prior to postoperative concurrent chemoradiotherapy for locoregionally advanced head and neck cancer.
Academic Article Time-dose relationship for local tumor control following alternate week concomitant radiation and chemotherapy of advanced head and neck cancer.
Academic Article p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines.
Academic Article A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFeradeā„¢ Biologic) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer undergoing reirradiation.
Academic Article Survival and selected outcomes of older adults with locally advanced head/neck cancer treated with chemoradiation therapy.
Academic Article Comparison of outcomes of locoregionally advanced oropharyngeal and non-oropharyngeal squamous cell carcinoma over two decades.
Academic Article Race and competing mortality in advanced head and neck cancer.
Academic Article Phase III randomized trial of induction chemotherapy in patients with N2 or N3 locally advanced head and neck cancer.
Academic Article Lymph node density--prognostic value in head and neck cancer.
Academic Article Reply to s. Chakraborty et al.
Academic Article Response-adapted volume de-escalation (RAVD) in locally advanced head and neck cancer.
Academic Article Final Results of a Randomized Phase 2 Trial Investigating the Addition of Cetuximab to Induction Chemotherapy and Accelerated or Hyperfractionated Chemoradiation for Locoregionally Advanced Head and Neck Cancer.
Academic Article A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFerade) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer (HNC).
Academic Article Integration of gefitinib (G), into a concurrent chemoradiation (CRT) regimen followed by G adjuvant therapy in patients with locally advanced head and neck cancer (HNC) - a Phase II Trial.
Academic Article Phase II trial pemetrexed-based induction chemotherapy followed by concomitant chemoradiotherapy in previously irradiated head and neck cancer patients.
Academic Article Management of Early Head and Neck Cancer in Elderly Patients.
Academic Article Baseline Computed Tomography Radiomic and Genomic Assessment of Head and Neck Squamous Cell Carcinoma.

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  • Head and Neck Neoplasms