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One or more keywords matched the following properties of Bader, Kenneth
keywords Diagnostic ultrasound
overview The focus of the Biomedical Acoustics Development and Engineering Research Laboratory (BADER Lab) is the translation of therapeutic ultrasound for non- or minimally invasive treatment of cardiovascular and cancerous disease. Specifically, we utilize acoustic cavitation for combinatorial ablation and enhanced drug delivery treatment strategies of pathologies resistant to standard interventional techniques. To assess bubble activity and the resultant changes in tissue structure, we are developing multi-modal imaging approaches via diagnostic ultrasound and magnetic resonance imaging. Analytic and numerical bubble dynamics models are also utilized to gain insight into the mechanism of action of our therapeutic approaches. Current research topics include: • Chronic thrombus ablation with histotripsy and thrombolytic drugs • Passive cavitation and MR imaging to assess histotripsy-induced liquefaction • In vitro assessment of histotripsy-enhanced drug delivery • Histotripsy-induced sonochemical reactions for the treatment of cancer • Numeric and analytic models of bubble dynamics • Magnetic Resonance-guided transurethral prostate ablation For more information, visit our laboratory website:
One or more keywords matched the following items that are connected to Bader, Kenneth
Item TypeName
Concept Ultrasonography
Concept Ultrasonography, Doppler
Academic Article Thrombolytic efficacy and enzymatic activity of rt-PA-loaded echogenic liposomes.
Academic Article Relationship between cavitation and loss of echogenicity from ultrasound contrast agents.
Academic Article Experimental validation of a finite-difference model for the prediction of transcranial ultrasound fields based on CT images.
Academic Article Broadband attenuation measurements of phospholipid-shelled ultrasound contrast agents.
Academic Article Quantitative Frequency-Domain Passive Cavitation Imaging.
Academic Article In vitro thrombolytic efficacy of echogenic liposomes loaded with tissue plasminogen activator and octafluoropropane gas.
Academic Article Assessment of histotripsy-induced liquefaction with diagnostic ultrasound and magnetic resonance imaging in vitro and ex vivo.
Academic Article Observation and modulation of the dissolution of histotripsy-induced bubble clouds with high-frame rate plane wave imaging.
Academic Article Ultrasound for Aesthetic Applications: A Review of Biophysical Mechanisms and Safety.
Academic Article Assessment of histological characteristics, imaging markers, and rt-PA susceptibility of ex vivo venous thrombi.
Academic Article Histotripsy Bubble Cloud Contrast With Chirp-Coded Excitation in Preclinical Models.
Academic Article Corrigendum: Assessment of histotripsy-induced liquefaction with diagnostic ultrasound and magnetic resonance imagingin vitroandex vivo(2019Phys. Med. Biol.64095023).
Academic Article Assessment of bubble activity generated by histotripsy combined with echogenic liposomes.
Academic Article Contrast-Enhanced Imaging of Histotripsy Bubble Clouds Using Chirp-Coded Excitation and Volterra Filtering.
Academic Article Development of Convolutional Neural Network to Segment Ultrasound Images of Histotripsy Ablation.
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