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A system for the continuous directed evolution of proteases rapidly reveals drug-resistance mutations.
A Panel of Protease-Responsive RNA Polymerases Respond to Biochemical Signals by Production of Defined RNA Outputs in Live Cells.
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays.
Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors.
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2.
Antiviral evaluation of hydroxyethylamine analogs: Inhibitors of SARS-CoV-2 main protease (3CLpro), a virtual screening and simulation approach.