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Barreiro, Luis
One or more keywords matched the following properties of Barreiro, Luis
PropertyValue
keywords Functional Genomics, Population Genetics, Natural Selection, Innate Immunity, Population Variation
overview Our lab aims to understand how natural selection has contributed to the evolution of our species and to which extent past selection events impact present-day susceptibility to disease. Specifically, our group studies the genetic basis of differences in immune response among different individuals and human populations as well as the phenotypic evolution of immune responses in primates. Most projects in the lab are multidisciplinary and combine the use of cutting edge genomic techniques with immunological and evolutionary genetic tools.
One or more keywords matched the following items that are connected to Barreiro, Luis
Item TypeName
Concept Genetics, Population
Concept Population Groups
Concept Population Dynamics
Concept Population
Academic Article Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations.
Academic Article The epigenomic landscape of African rainforest hunter-gatherers and farmers.
Academic Article Evolutionary genetics evidence of an essential, nonredundant role of the IFN-? pathway in protective immunity.
Academic Article Inferring the demographic history of African farmers and pygmy hunter-gatherers using a multilocus resequencing data set.
Academic Article The contribution of admixture to primate evolution.
Academic Article The heritage of pathogen pressures and ancient demography in the human innate-immunity CD209/CD209L region.
Academic Article DC-SIGNR neck-region polymorphisms and HIV-1 susceptibility: From population stratification to a possible advantage of the 7/5 heterozygous genotype.
Academic Article Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America.
Academic Article Natural selection has driven population differentiation in modern humans.
Academic Article From evolutionary genetics to human immunology: how selection shapes host defence genes.
Academic Article The demographic history and mutational load of African hunter-gatherers and farmers.
Academic Article Functional characterization of naturally occurring genetic variants in the human TLR1-2-6 gene family.
Academic Article DC-SIGN interacts with Mycobacterium leprae but sequence variation in this lectin is not associated with leprosy in the Pakistani population.
Academic Article Formulating a historical and demographic model of recent human evolution based on resequencing data from noncoding regions.
Academic Article Exploring the occurrence of classic selective sweeps in humans using whole-genome sequencing data sets.
Academic Article Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense.
Academic Article Genetic and evolutionary determinants of human population variation in immune responses.
Academic Article Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens.
Academic Article Signatures of purifying and local positive selection in human miRNAs.
Academic Article Polygenic adaptation and convergent evolution on growth and cardiac genetic pathways in African and Asian rainforest hunter-gatherers.
Academic Article Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes.
Academic Article Evolutionary and population (epi)genetics of immunity to infection.
Grant Stress and the Genome: Testing the Impact of Social Effects on Gene Regulation
Academic Article Shaping immunity: The influence of natural selection on population immune diversity.
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  • Population