Item Type | Name |
Concept
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Thyroxine
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Academic Article
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Effects of rexinoids on thyrotrope function and the hypothalamic-pituitary-thyroid axis.
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Academic Article
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Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage.
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Academic Article
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Coordination of hypothalamic and pituitary T3 production regulates TSH expression.
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Academic Article
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Type 2 deiodinase at the crossroads of thyroid hormone action.
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Academic Article
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Thyroxine 5'-deiodination mediates norepinephrine-induced lipogenesis in dispersed brown adipocytes.
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Academic Article
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[Thyroxine (T4) to 3,5,3'-triiodothyronine (T3) and 3,3',5'-triiodothyronine (reverse T3) conversion in human leukocyte suspensions. Study in hyper and hypothyroidism states].
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Academic Article
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Evidence of UCP1-independent regulation of norepinephrine-induced thermogenesis in brown fat.
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Academic Article
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Hormonal regulation of malic enzyme and glucose-6-phosphate dehydrogenase in brown adipose tissue.
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Academic Article
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Of rats and men: thyroid homeostasis in rodents and human beings - Authors' reply.
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Academic Article
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Thyroid Hormone Signaling in Male Mouse Skeletal Muscle Is Largely Independent of D2 in Myocytes.
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Academic Article
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Thyroid function disturbance and type 3 iodothyronine deiodinase induction after myocardial infarction in rats a time course study.
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Academic Article
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Systemic Thyroid Hormone Status During Levothyroxine Therapy In Hypothyroidism: A Systematic Review and Meta-Analysis.
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Academic Article
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Is a Normal TSH Synonymous With "Euthyroidism" in Levothyroxine Monotherapy?
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Academic Article
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Thyroid hormone activation by type 2 deiodinase mediates exercise-induced peroxisome proliferator-activated receptor-? coactivator-1a expression in skeletal muscle.
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Academic Article
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Optimal response of key enzymes and uncoupling protein to cold in BAT depends on local T3 generation.
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Academic Article
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Selective proteolysis of human type 2 deiodinase: a novel ubiquitin-proteasomal mediated mechanism for regulation of hormone activation.
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Academic Article
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Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling.
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Academic Article
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Ubc6p and ubc7p are required for normal and substrate-induced endoplasmic reticulum-associated degradation of the human selenoprotein type 2 iodothyronine monodeiodinase.
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Academic Article
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Thyroxine induced transformation in sarcoplasmic reticulum of rabbit soleus and psoas muscles.
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Academic Article
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Substrate-induced down-regulation of human type 2 deiodinase (hD2) is mediated through proteasomal degradation and requires interaction with the enzyme's active center.
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Academic Article
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Mice with impaired extrathyroidal thyroxine to 3,5,3'-triiodothyronine conversion maintain normal serum 3,5,3'-triiodothyronine concentrations.
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Academic Article
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Atypical expression of type 2 iodothyronine deiodinase in thyrotrophs explains the thyroxine-mediated pituitary thyrotropin feedback mechanism.
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Academic Article
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Endoplasmic reticulum-associated degradation of the human type 2 iodothyronine deiodinase (D2) is mediated via an association between mammalian UBC7 and the carboxyl region of D2.
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Academic Article
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For some, L-thyroxine replacement might not be enough: a genetic rationale.
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Academic Article
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Hypothyroidism.
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Academic Article
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Pathophysiological relevance of deiodinase polymorphism.
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Academic Article
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Neuropeptide Y1 and Y5 receptors mediate the effects of neuropeptide Y on the hypothalamic-pituitary-thyroid axis.
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Academic Article
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Triumphs of the thyroid despite lesser conversion.
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Academic Article
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Central role of brown adipose tissue thyroxine 5'-deiodinase on thyroid hormone-dependent thermogenic response to cold.
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Academic Article
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Guidelines for the treatment of hypothyroidism: prepared by the american thyroid association task force on thyroid hormone replacement.
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Academic Article
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Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation.
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Academic Article
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Coupling between Nutrient Availability and Thyroid Hormone Activation.
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Academic Article
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Intracellular conversion of thyroxine to triiodothyronine is required for the optimal thermogenic function of brown adipose tissue.
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Academic Article
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An inside job.
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Academic Article
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Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse.
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Academic Article
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Extrathyroidal conversion of thyroxine to 3,5,3'-triiodothyronine in cold-acclimated thyroxine-maintained thyroidectomized rats.
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Academic Article
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Defending plasma T3 is a biological priority.
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Academic Article
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Conversion of thyroxine (T4) to T3 and rT3 in human leucocyte suspension: its application to clinical investigation.
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Academic Article
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Deiodinase-mediated thyroid hormone inactivation minimizes thyroid hormone signaling in the early development of fetal skeleton.
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Academic Article
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[Basedow-Graves' disease: analysis of various parameters in the prognosis of remission after clinical treatment].
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Academic Article
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Thyroid function in critically ill patients.
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Academic Article
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New insights into the variable effectiveness of levothyroxine monotherapy for hypothyroidism.
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Academic Article
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Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine.
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Academic Article
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Spared bone mass in rats treated with thyroid hormone receptor TR beta-selective compound GC-1.
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Academic Article
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Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eIF2a-mediated decrease in type 2 deiodinase synthesis.
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Academic Article
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Effects of thyroid hormone administration and estrogen deficiency on bone mass of female rats.
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Academic Article
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Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain.
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Academic Article
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Severe and mild neonatal hypothyroidism mediate opposite effects on Leydig cells of rats.
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Academic Article
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Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells.
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Academic Article
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Possible mechanism of action of cholesterol enriched diet on the thyroid.
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Academic Article
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An Online Survey of Hypothyroid Patients Demonstrates Prominent Dissatisfaction.
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Academic Article
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Cracking the code for thyroid hormone signaling.
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Academic Article
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Adenosine 3',5'-monophosphate and thyroid hormone control of uncoupling protein messenger ribonucleic acid in freshly dispersed brown adipocytes.
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Academic Article
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3,5,3'-Triiodothyronine actively stimulates UCP in brown fat under minimal sympathetic activity.
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Academic Article
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The role of glucocorticoids in the stress-induced reduction of extrathyroidal 3,5,3'-triiodothyronine generation in rats.
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Academic Article
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Higher Caloric Exposure in Critically Ill Patients Transiently Accelerates Thyroid Hormone Activation.
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Academic Article
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Levothyroxine treatment and cholesterol in hypothyroidism.
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Academic Article
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Individualized Therapy for Hypothyroidism: Is T4 Enough for Everyone?
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Academic Article
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Iodine Deficiency Increases Fat Contribution to Energy Expenditure in Male Mice.
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Academic Article
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Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidism: A Consensus Document.
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Academic Article
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Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidism: A Consensus Document.
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Academic Article
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Use of Statins Among Patients Taking Levothyroxine: an Observational Drug Utilization Study Across Sites.
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Academic Article
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Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism.
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Academic Article
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Neonatal thyroxine activation modifies epigenetic programming of the liver.
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Academic Article
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Response to Letter to the Editor From Bonnema et al: "Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine + Liothyronine in Hypothyroidism".
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Academic Article
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Brain Fog in Hypothyroidism: Understanding the Patient's Perspective.
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Academic Article
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Primary hypothyroidism and quality of life.
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Academic Article
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The relevance of T3 in the management of hypothyroidism.
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Academic Article
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Selpercatinib-Induced Hypothyroidism Through Off-Target Inhibition of Type 2 Iodothyronine Deiodinase.
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Academic Article
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Multisensory Stimulation Improves Cognition and Behavior in Adult Male Rats Born to LT4-treated Thyroidectomized Dams.
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Academic Article
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T3 levels and thyroid hormone signaling.
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Academic Article
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Serum Thyrotropin and Triiodothyronine Levels in Levothyroxine-treated Patients.
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Grant
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Selenodeiodinase processing by the proteasome system
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Grant
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Selenodeidinase Processing by the Proteasome System
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Academic Article
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Are We Restoring Thyroid Hormone Signaling in Levothyroxine-Treated Patients With Residual Symptoms of Hypothyroidism?
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Academic Article
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Demographic, Healthcare Access, and Dietary Factors Associated With Thyroid Hormone Treatments for Hypothyroidism.
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Academic Article
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Levothyroxine Treatment Adequacy and Formulation Changes in Patients with Hypothyroidism: A Retrospective Study of Real-World Data from the United States.
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Academic Article
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The Effects of Patient Characteristics on the Management of Subclinical Hypothyroidism: A Survey of Faculty and Trainees.
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Academic Article
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Emerging Therapies in Hypothyroidism.
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Academic Article
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A Cross-Sectional Analysis of Cardiovascular and Bone Health Care Utilization During Treatment With Thyroid Hormone.
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Academic Article
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Sustained Pituitary T3 Production Explains the T4-mediated TSH Feedback Mechanism.
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Academic Article
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Thyroid hormone homeostasis in levothyroxine-treated patients: Findings from ELSA-Brasil.
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