| Item Type | Name |
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Concept
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Triiodothyronine
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Concept
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Triiodothyronine, Reverse
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Academic Article
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Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis.
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Academic Article
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Thyroid hormone--sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform--specific.
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Academic Article
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Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats.
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Academic Article
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Cold exposure rapidly induces virtual saturation of brown adipose tissue nuclear T3 receptors.
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Academic Article
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Coordination of hypothalamic and pituitary T3 production regulates TSH expression.
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Academic Article
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Type 2 deiodinase at the crossroads of thyroid hormone action.
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Academic Article
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Early Developmental Disruption of Type 2 Deiodinase Pathway in Mouse Skeletal Muscle Does Not Impair Muscle Function.
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Academic Article
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[Thyroxine (T4) to 3,5,3'-triiodothyronine (T3) and 3,3',5'-triiodothyronine (reverse T3) conversion in human leukocyte suspensions. Study in hyper and hypothyroidism states].
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Academic Article
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Evidence of UCP1-independent regulation of norepinephrine-induced thermogenesis in brown fat.
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Academic Article
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Hormonal regulation of malic enzyme and glucose-6-phosphate dehydrogenase in brown adipose tissue.
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Academic Article
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Of rats and men: thyroid homeostasis in rodents and human beings - Authors' reply.
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Academic Article
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Thyroid Hormone Signaling in Male Mouse Skeletal Muscle Is Largely Independent of D2 in Myocytes.
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Academic Article
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The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue.
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Academic Article
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Thyroid function disturbance and type 3 iodothyronine deiodinase induction after myocardial infarction in rats a time course study.
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Academic Article
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Is a Normal TSH Synonymous With "Euthyroidism" in Levothyroxine Monotherapy?
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Academic Article
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Thyroid hormone activation by type 2 deiodinase mediates exercise-induced peroxisome proliferator-activated receptor-? coactivator-1a expression in skeletal muscle.
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Academic Article
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Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway.
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Academic Article
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Optimal response of key enzymes and uncoupling protein to cold in BAT depends on local T3 generation.
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Academic Article
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Selective proteolysis of human type 2 deiodinase: a novel ubiquitin-proteasomal mediated mechanism for regulation of hormone activation.
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Academic Article
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Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling.
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Academic Article
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Induction of Type 2 Iodothyronine Deiodinase After Status Epilepticus Modifies Hippocampal Gene Expression in Male Mice.
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Academic Article
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Ubc6p and ubc7p are required for normal and substrate-induced endoplasmic reticulum-associated degradation of the human selenoprotein type 2 iodothyronine monodeiodinase.
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Academic Article
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Substrate-induced down-regulation of human type 2 deiodinase (hD2) is mediated through proteasomal degradation and requires interaction with the enzyme's active center.
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Academic Article
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Mice with impaired extrathyroidal thyroxine to 3,5,3'-triiodothyronine conversion maintain normal serum 3,5,3'-triiodothyronine concentrations.
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Academic Article
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Thyroid hormone-related regulation of gene expression in human fatty liver.
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Academic Article
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Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.
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Academic Article
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Atypical expression of type 2 iodothyronine deiodinase in thyrotrophs explains the thyroxine-mediated pituitary thyrotropin feedback mechanism.
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Academic Article
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Endoplasmic reticulum-associated degradation of the human type 2 iodothyronine deiodinase (D2) is mediated via an association between mammalian UBC7 and the carboxyl region of D2.
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Academic Article
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For some, L-thyroxine replacement might not be enough: a genetic rationale.
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Academic Article
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Maternal inheritance of an inactive type III deiodinase gene allele affects mouse pancreatic ß-cells and disrupts glucose homeostasis.
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Academic Article
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Pathophysiological relevance of deiodinase polymorphism.
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Academic Article
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Neuropeptide Y1 and Y5 receptors mediate the effects of neuropeptide Y on the hypothalamic-pituitary-thyroid axis.
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Academic Article
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Triumphs of the thyroid despite lesser conversion.
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Academic Article
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Central role of brown adipose tissue thyroxine 5'-deiodinase on thyroid hormone-dependent thermogenic response to cold.
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Academic Article
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Impaired metabolic effects of a thyroid hormone receptor beta-selective agonist in a mouse model of diet-induced obesity.
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Academic Article
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Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation.
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Academic Article
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Coupling between Nutrient Availability and Thyroid Hormone Activation.
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Academic Article
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Intracellular conversion of thyroxine to triiodothyronine is required for the optimal thermogenic function of brown adipose tissue.
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Academic Article
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Triiodothyronine amplifies norepinephrine stimulation of uncoupling protein gene transcription by a mechanism not requiring protein synthesis.
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Academic Article
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Myocardial Inactivation of Thyroid Hormones in Patients with Aortic Stenosis.
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Academic Article
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An inside job.
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Academic Article
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Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse.
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Academic Article
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The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure.
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Academic Article
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Extrathyroidal conversion of thyroxine to 3,5,3'-triiodothyronine in cold-acclimated thyroxine-maintained thyroidectomized rats.
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Academic Article
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Defending plasma T3 is a biological priority.
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Academic Article
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Conversion of thyroxine (T4) to T3 and rT3 in human leucocyte suspension: its application to clinical investigation.
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Academic Article
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The small polyphenolic molecule kaempferol increases cellular energy expenditure and thyroid hormone activation.
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Academic Article
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Metal Coordinated Poly-Zinc-Liothyronine Provides Stable Circulating Triiodothyronine Levels in Hypothyroid Rats.
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Academic Article
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A TRbeta-selective agonist confers resistance to diet-induced obesity.
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Academic Article
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Deiodinase-mediated thyroid hormone inactivation minimizes thyroid hormone signaling in the early development of fetal skeleton.
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Academic Article
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Nuclear 3,5,3'-triiodothyronine (T3) in brown adipose tissue: receptor occupancy and sources of T3 as determined by in vivo techniques.
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Academic Article
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[Basedow-Graves' disease: analysis of various parameters in the prognosis of remission after clinical treatment].
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Academic Article
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New insights into the variable effectiveness of levothyroxine monotherapy for hypothyroidism.
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Academic Article
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Spared bone mass in rats treated with thyroid hormone receptor TR beta-selective compound GC-1.
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Academic Article
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Type 2 Deiodinase Disruption in Astrocytes Results in Anxiety-Depressive-Like Behavior in Male Mice.
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Academic Article
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Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eIF2a-mediated decrease in type 2 deiodinase synthesis.
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Academic Article
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Transcriptional and posttranscriptional mechanisms in uncoupling protein mRNA response to cold.
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Academic Article
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Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain.
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Academic Article
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Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells.
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Academic Article
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Possible mechanism of action of cholesterol enriched diet on the thyroid.
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Academic Article
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Cardiac expression of human type 2 iodothyronine deiodinase increases glucose metabolism and protects against doxorubicin-induced cardiac dysfunction in male mice.
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Academic Article
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Cracking the code for thyroid hormone signaling.
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Academic Article
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Adenosine 3',5'-monophosphate and thyroid hormone control of uncoupling protein messenger ribonucleic acid in freshly dispersed brown adipocytes.
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Academic Article
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Thyroid hormone receptor beta-specific agonist GC-1 increases energy expenditure and prevents fat-mass accumulation in rats.
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Academic Article
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3,5,3'-Triiodothyronine actively stimulates UCP in brown fat under minimal sympathetic activity.
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Academic Article
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The role of glucocorticoids in the stress-induced reduction of extrathyroidal 3,5,3'-triiodothyronine generation in rats.
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Academic Article
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Higher Caloric Exposure in Critically Ill Patients Transiently Accelerates Thyroid Hormone Activation.
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Academic Article
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Liothyronine and Desiccated Thyroid Extract in the Treatment of Hypothyroidism.
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Academic Article
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Thyroid hormone stimulation of osteocalcin gene expression in ROS 17/2.8 cells is mediated by transcriptional and post-transcriptional mechanisms.
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Academic Article
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Individualized Therapy for Hypothyroidism: Is T4 Enough for Everyone?
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Academic Article
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Human Type 1 Iodothyronine Deiodinase (DIO1) Mutations Cause Abnormal Thyroid Hormone Metabolism.
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Academic Article
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Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidism: A Consensus Document.
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Academic Article
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Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidism: A Consensus Document.
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Academic Article
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Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism.
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Academic Article
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Neonatal thyroxine activation modifies epigenetic programming of the liver.
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Academic Article
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Extended Absorption of Liothyronine from Poly-Zinc-Liothyronine: Results from a Phase 1, Double-Blind, Randomized, and Controlled Study in Humans.
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Academic Article
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Deiodinase-3 is a thyrostat to regulate podocyte homeostasis.
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Academic Article
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Response to Letter to the Editor From Bonnema et al: "Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine + Liothyronine in Hypothyroidism".
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Academic Article
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Primary hypothyroidism and quality of life.
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Academic Article
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Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse.
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Academic Article
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The relevance of T3 in the management of hypothyroidism.
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Academic Article
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T3 levels and thyroid hormone signaling.
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Academic Article
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Serum Thyrotropin and Triiodothyronine Levels in Levothyroxine-treated Patients.
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Grant
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Metabolic and Xenobiotic Control of Thyroid Hormone Metabolism
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Academic Article
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Are We Restoring Thyroid Hormone Signaling in Levothyroxine-Treated Patients With Residual Symptoms of Hypothyroidism?
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Academic Article
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Demographic, Healthcare Access, and Dietary Factors Associated With Thyroid Hormone Treatments for Hypothyroidism.
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Academic Article
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Emerging Therapies in Hypothyroidism.
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Academic Article
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A Cross-Sectional Analysis of Cardiovascular and Bone Health Care Utilization During Treatment With Thyroid Hormone.
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Academic Article
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Sustained Pituitary T3 Production Explains the T4-mediated TSH Feedback Mechanism.
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Academic Article
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Editorial: (Re)defining hypothyroidism: the key to patient-centered treatment.
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