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Pincus, David
One or more keywords matched the following items that are connected to Pincus, David
Item TypeName
Concept Saccharomyces cerevisiae Proteins
Concept Saccharomyces cerevisiae
Academic Article Hsf1 Phosphorylation Generates Cell-to-Cell Variation in Hsp90 Levels and Promotes Phenotypic Plasticity.
Academic Article Engineering allosteric regulation in protein kinases.
Academic Article Genetic and epigenetic determinants establish a continuum of Hsf1 occupancy and activity across the yeast genome.
Academic Article Hsf1 and Hsp70 constitute a two-component feedback loop that regulates the yeast heat shock response.
Academic Article Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation.
Academic Article BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response.
Academic Article Translocon Declogger Ste24 Protects against IAPP Oligomer-Induced Proteotoxicity.
Academic Article tRNA thiolation links translation to stress responses in Saccharomyces cerevisiae.
Academic Article Formation of subnuclear foci is a unique spatial behavior of mating MAPKs during hyperosmotic stress.
Academic Article Specificity in endoplasmic reticulum-stress signaling in yeast entails a step-wise engagement of HAC1 mRNA to clusters of the stress sensor Ire1.
Academic Article Size doesn't matter in the heat shock response.
Academic Article Unrestrained AMPylation targets cytosolic chaperones and activates the heat shock response.
Academic Article Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis.
Academic Article Assigning quantitative function to post-translational modifications reveals multiple sites of phosphorylation that tune yeast pheromone signaling output.
Academic Article Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range.
Academic Article Negative feedback that improves information transmission in yeast signalling.
Academic Article Lipidomic Analysis of a-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment.
Academic Article Heat Shock Factor 1 Drives Intergenic Association of Its Target Gene Loci upon Heat Shock.
Academic Article Proteotoxicity from aberrant ribosome biogenesis compromises cell fitness.
Academic Article Messenger RNA targeting to endoplasmic reticulum stress signalling sites.
Academic Article m6A modification of a 3' UTR site reduces RME1 mRNA levels to promote meiosis.
Academic Article Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses.
Academic Article Multi-kinase control of environmental stress responsive transcription.
Academic Article Subcellular localization of the J-protein Sis1 regulates the heat shock response.
Academic Article Primordial super-enhancers: heat shock-induced chromatin organization in yeast.
Academic Article Inducible transcriptional condensates drive 3D genome reorganization in the heat shock response.
Academic Article Transcriptional regulation of Sis1 promotes fitness but not feedback in the heat shock response.
Academic Article Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates.
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  • Saccharomyces