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overview Our group focuses on computational approaches to discover and characterize context-specific genetic effects on complex disorders. This includes polygenic methods for gene-environment interaction, gene-gene interaction, and genetic subtypes of disease. We are particularly interested in applications to asthma, major depressive disorder, single cell omics, and cross-population portability of genetic predictions. Our long-term goal is to advance equitable precision treatment by embracing the full diversity of human contexts.
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  • Gene Environment Interaction