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One or more keywords matched the following items that are connected to Koya, Richard
Item TypeName
Concept Acute Disease
Concept Actins
Concept Adenocarcinoma
Concept Atractyloside
Concept Adaptation, Physiological
Concept Biphenyl Compounds
Concept Bone Marrow Cells
Concept Aging
Concept Antineoplastic Agents
Concept Carcinoma, Squamous Cell
Concept Aminopyridines
Concept Antineoplastic Combined Chemotherapy Protocols
Concept Analysis of Variance
Concept Antibodies, Monoclonal
Concept Histocompatibility Antigens Class II
Concept Base Sequence
Concept DNA Damage
Concept Azacitidine
Concept Carcinoma, Renal Cell
Concept Biopsy
Concept Carbonic Anhydrases
Concept Cell Division
Concept Cell Separation
Concept Chromosomes, Human, Pair 15
Concept Colonic Neoplasms
Concept Chromosome Mapping
Concept Genetic Vectors
Concept Dacarbazine
Concept Complement C3
Concept Imidazoles
Concept Cysteine Endopeptidases
Concept Cytochrome c Group
Concept Cytological Techniques
Concept Dendritic Cells
Concept Cytotoxicity, Immunologic
Concept Chemotaxis, Leukocyte
Concept Kidney Neoplasms
Concept Exons
Concept Cost-Benefit Analysis
Concept Diagnostic Imaging
Concept Cytomegalovirus
Concept Drug Evaluation, Preclinical
Concept Fibrinogen
Concept Enzyme Activation
Concept Microtubule-Associated Proteins
Concept Gene Expression Regulation
Concept Glioma
Concept Nucleic Acid Hybridization
Concept Genetic Engineering
Concept T-Lymphocytes, Helper-Inducer
Concept Hematopoietic Stem Cells
Concept Drug Combinations
Concept Liposomes
Concept Enzyme-Linked Immunosorbent Assay
Concept Hydroxamic Acids
Concept Flow Cytometry
Concept Gene Amplification
Concept Granulocytes
Concept Leukocytes, Mononuclear
Concept Macrophages
Concept Membrane Glycoproteins
Concept Lymphocyte Culture Test, Mixed
Concept Hydrolysis
Concept Mice, Transgenic
Concept Models, Genetic
Concept Neutropenia
Concept Markov Chains
Concept Extracellular Matrix
Concept Immunohistochemistry
Concept Mice, Inbred BALB C
Concept Mice, Inbred C57BL
Concept Mice, Nude
Concept Mutation
Concept HeLa Cells
Concept Neutrophils
Concept Phosphatidylinositols
Concept Ovarian Neoplasms
Concept Lipopolysaccharides
Concept Lung Neoplasms
Concept Major Histocompatibility Complex
Concept NAD
Concept Porphyrins
Concept Prostatic Neoplasms
Concept Piperazines
Concept Frozen Sections
Concept Histocompatibility Antigens
Concept Repressor Proteins
Concept Genes, ras
Concept HLA-A2 Antigen
Concept Sensitivity and Specificity
Concept Humans
Concept Listeria monocytogenes
Concept Cluster Analysis
Concept Tomography, X-Ray Computed
Concept Transcription, Genetic
Concept Protein Biosynthesis
Concept Interferon Type I
Concept Intracellular Membranes
Concept Gram-Positive Bacterial Infections
Concept Tumor Necrosis Factor-alpha
Concept Testis
Concept Genetic Variation
Concept Protein Engineering
Concept HLA-A Antigens
Concept Vaccination
Concept CD28 Antigens
Concept Histocompatibility Antigens Class I
Concept Leukemia, Myeloid
Concept Transduction, Genetic
Concept Herpesvirus 1, Human
Concept Hematopoietic Stem Cell Transplantation
Concept Th1 Cells
Concept Gene Library
Concept Cell Culture Techniques
Concept Drug Resistance, Neoplasm
Concept Antibodies, Blocking
Concept Intramolecular Oxidoreductases
Concept Reverse Transcriptase Polymerase Chain Reaction
Concept Caspases
Concept Tumor Cells, Cultured
Concept Mitogen-Activated Protein Kinases
Concept S Phase
Concept Transforming Growth Factor beta
Concept NF-kappa B
Concept Central Nervous System Neoplasms
Concept Cell Adhesion Molecules
Concept Up-Regulation
Concept G1 Phase
Concept PC12 Cells
Concept Muromonab-CD3
Concept Antigens, CD
Concept 3T3 Cells
Concept Mitochondria
Concept CD4-Positive T-Lymphocytes
Concept Interleukin-4
Concept Receptor, Macrophage Colony-Stimulating Factor
Concept Immunotherapy, Adoptive
Concept Lymphocytes, Tumor-Infiltrating
Concept Gene Expression
Concept Stem Cell Transplantation
Concept T-Lymphocyte Subsets
Concept Sequence Analysis, DNA
Concept Methylation
Concept Genes, Reporter
Concept Mitochondria, Liver
Concept Treatment Outcome
Concept Gene Transfer Techniques
Concept MAP Kinase Kinase 1
Concept B7-1 Antigen
Concept Mice, Knockout
Concept CD8-Positive T-Lymphocytes
Concept DNA, Complementary
Concept Cell Proliferation
Concept Antigens, CD34
Concept Thapsigargin
Concept ras Proteins
Concept Interleukin-12
Concept Apoptosis Regulatory Proteins
Concept Th2 Cells
Concept Antineoplastic Agents, Alkylating
Concept Transgenes
Concept Staurosporine
Concept Cancer Vaccines
Concept Caspase 3
Concept Fas Ligand Protein
Concept Tumor Necrosis Factor Receptor Superfamily, Member 9
Concept MAP Kinase Kinase Kinases
Concept Genes, T-Cell Receptor
Concept eIF-2 Kinase
Concept Mutation, Missense
Concept Lymphocyte Count
Concept Lipopolysaccharide Receptors
Concept Jurkat Cells
Concept In Situ Hybridization, Fluorescence
Concept Lab-On-A-Chip Devices
Concept Myofibroblasts
Concept Single-Cell Analysis
Concept Exome
Concept Clonal Evolution
Concept Positron-Emission Tomography
Concept Proteomics
Concept bcl-2-Associated X Protein
Concept Proto-Oncogene Proteins c-bcl-2
Concept Amino Acid Substitution
Concept Proto-Oncogene Proteins B-raf
Concept Indoleamine-Pyrrole 2,3,-Dioxygenase
Concept Oligonucleotide Array Sequence Analysis
Concept Adoptive Transfer
Concept Mitogen-Activated Protein Kinase Kinases
Concept CD40 Ligand
Concept Gene Expression Profiling
Concept Antineoplastic Protocols
Concept bcl-X Protein
Concept Photochemotherapy
Concept Promoter Regions, Genetic
Concept Mice
Concept Caspase 8
Concept Pyrimidinones
Concept Pyrroles
Concept Chemokine CCL1
Concept Saccharomyces cerevisiae
Concept Unfolded Protein Response
Concept HEK293 Cells
Concept Molecular Targeted Therapy
Concept Rats
Concept Natural Killer T-Cells
Concept Cell Engineering
Concept Antibodies, Monoclonal, Humanized
Concept CTLA-4 Antigen
Concept Spleen
Concept Vancomycin
Concept T-Lymphocytes, Cytotoxic
Concept Blotting, Western
Concept Monitoring, Immunologic
Concept Down-Regulation
Concept PTEN Phosphohydrolase
Concept Survival Analysis
Concept Hepacivirus
Concept DNA Copy Number Variations
Concept Molecular Imaging
Concept Open Reading Frames
Concept Transfection
Concept Blotting, Northern
Concept Electrophoresis, Gel, Two-Dimensional
Concept Reproducibility of Results
Concept Genetic Therapy
Concept Genome, Human
Concept Killer Cells, Lymphokine-Activated
Concept Survival Rate
Concept Polymerase Chain Reaction
Concept Amyloid beta-Peptides
Concept HL-60 Cells
Concept Chemokine CCL2
Concept DNA Methylation
Concept Receptors, CCR2
Concept Interleukin-17
Concept Gene Silencing
Concept Imaging, Three-Dimensional
Concept Xenograft Model Antitumor Assays
Concept Hematologic Neoplasms
Concept Histone Deacetylase Inhibitors
Concept Phosphatidylinositol 3-Kinases
Concept K562 Cells
Concept Genes, Transgenic, Suicide
Concept Extracellular Signal-Regulated MAP Kinases
Concept T-Lymphocytes, Regulatory
Concept gp100 Melanoma Antigen
Concept B7-2 Antigen
Concept TNF-Related Apoptosis-Inducing Ligand
Concept Granzymes
Concept NK Cell Lectin-Like Receptor Subfamily A
Concept Precision Medicine
Concept Tumor Microenvironment
Concept Lectins, C-Type
Concept Programmed Cell Death 1 Receptor
Concept Cell Line, Tumor
Concept T Cell Transcription Factor 1
Concept MART-1 Antigen
Concept Alzheimer Disease
Concept Antibodies
Concept Brain Neoplasms
Concept Calcium
Concept Cell Line
Concept Cell Survival
Concept Cells, Cultured
Concept Clinical Trials as Topic
Concept Cloning, Molecular
Concept Disease Models, Animal
Concept DNA Restriction Enzymes
Concept DNA, Single-Stranded
Concept Drug Resistance, Microbial
Concept Drug Screening Assays, Antitumor
Concept Fever
Concept Histidine
Concept Immunoglobulins
Concept Kinetics
Concept Lymphocyte Activation
Concept Lymphocytes
Concept Membrane Potentials
Concept Monocytes
Concept Nitrophenols
Concept Protoporphyrins
Concept Pyridones
Concept Recombinant Fusion Proteins
Concept Retrospective Studies
Concept T-Lymphocytes
Concept Thymus Gland
Concept Uveal Neoplasms
Concept Gene Expression Regulation, Neoplastic
Concept Immunophenotyping
Concept Granulocyte-Macrophage Colony-Stimulating Factor
Concept Cytokines
Concept Mice, SCID
Concept Mice, Inbred NOD
Concept Sequence Analysis, RNA
Concept DNA Primers
Concept Gelsolin
Concept Coculture Techniques
Concept Computational Biology
Concept Complementarity Determining Regions
Concept MicroRNAs
Concept Intracellular Space
Concept Epigenesis, Genetic
Concept Protein Kinase Inhibitors
Concept Caspase 9
Academic Article A novel AKT1 mutant amplifies an adaptive melanoma response to BRAF inhibition.
Academic Article Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy.
Academic Article MHC-I-restricted melanoma antigen specific TCR-engineered human CD4+ T cells exhibit multifunctional effector and helper responses, in vitro.
Academic Article Active Immunotherapy of Cancer.
Academic Article CTLA4 blockade broadens the peripheral T-cell receptor repertoire.
Academic Article Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma.
Academic Article Exposure to a histone deacetylase inhibitor has detrimental effects on human lymphocyte viability and function.
Academic Article The oncogenic BRAF kinase inhibitor PLX4032/RG7204 does not affect the viability or function of human lymphocytes across a wide range of concentrations.
Academic Article Efficient identification of neoantigen-specific T-cell responses in advanced human ovarian cancer.
Academic Article A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells.
Academic Article WHSC1/NSD2 regulates immune infiltration in prostate cancer.
Academic Article CTLA4 blockade increases Th17 cells in patients with metastatic melanoma.
Academic Article Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation.
Academic Article Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance.
Academic Article A rare population of tumor antigen-specific CD4+CD8+ double-positive aß T lymphocytes uniquely provide CD8-independent TCR genes for engineering therapeutic T cells.
Academic Article Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy.
Academic Article HSV-sr39TK positron emission tomography and suicide gene elimination of human hematopoietic stem cells and their progeny in humanized mice.
Academic Article Cellular Immunotherapy in the Treatment of Hematopoietic Malignancies.
Academic Article The impact of ex vivo clinical grade activation protocols on human T-cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy.
Academic Article Modulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanoma.
Academic Article Rapid Construction of Antitumor T-cell Receptor Vectors from Frozen Tumors for Engineered T-cell Therapy.
Academic Article BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy.
Academic Article Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment.
Academic Article Natural killer T cells in advanced melanoma patients treated with tremelimumab.
Academic Article Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses.
Academic Article Dendritic cell-based immunotherapy in prevention and treatment of renal cell carcinoma: efficacy, safety, and activity of Ad-GM·CAIX in immunocompetent mouse models.
Academic Article CTLA4 blockade induces frequent tumor infiltration by activated lymphocytes regardless of clinical responses in humans.
Academic Article Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell lines.
Academic Article Transduction of acute myeloid leukemia cells with third generation self-inactivating lentiviral vectors expressing CD80 and GM-CSF: effects on proliferation, differentiation, and stimulation of allogeneic and autologous anti-leukemia immune responses.
Academic Article Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy.
Academic Article Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
Academic Article Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.
Academic Article A cloning method for caspase substrates that uses the yeast two-hybrid system: cloning of the antiapoptotic gene gelsolin.
Academic Article Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release.
Academic Article Human antigen-specific regulatory T cells generated by T cell receptor gene transfer.
Academic Article Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines.
Academic Article Lentiviral vectors with CMV or MHCII promoters administered in vivo: immune reactivity versus persistence of expression.
Academic Article Measurement and Quantitative Characterization of Whole-Body Pharmacokinetics of Exogenously Administered T Cells in Mice.
Academic Article Distinct immunological mechanisms of CTLA-4 and PD-1 blockade revealed by analyzing TCR usage in blood lymphocytes.
Academic Article Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma.
Academic Article A novel series of conferences tackling the hurdles confronting the translation of novel cancer immunotherapies.
Academic Article Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC.
Academic Article CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model.
Academic Article The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity.
Academic Article Gelsolin functions as a metastasis suppressor in B16-BL6 mouse melanoma cells and requirement of the carboxyl-terminus for its effect.
Academic Article Potent maturation of monocyte-derived dendritic cells after CD40L lentiviral gene delivery.
Academic Article siRNA knockdown of ribonucleotide reductase inhibits melanoma cell line proliferation alone or synergistically with temozolomide.
Academic Article Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas ligand pathway.
Academic Article The use of lentiviral vectors in gene therapy of leukemia: combinatorial gene delivery of immunomodulators into leukemia cells by state-of-the-art vectors.
Academic Article Analysis of the value of empiric vancomycin administration in febrile neutropenia occurring after autologous peripheral blood stem cell transplants.
Academic Article Preexisting MEK1 exon 3 mutations in V600E/KBRAF melanomas do not confer resistance to BRAF inhibitors.
Academic Article RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.
Academic Article Monocytes transduced with lentiviral vectors expressing hepatitis C virus non-structural proteins and differentiated into dendritic cells stimulate multi-antigenic CD8(+) T cell responses.
Academic Article Synthesis, Tumor Specificity, and Photosensitizing Efficacy of Erlotinib-Conjugated Chlorins and Bacteriochlorins: Identification of a Highly Effective Candidate for Photodynamic Therapy of Cancer.
Academic Article T cell receptor (TCR)-transgenic CD8 lymphocytes rendered insensitive to transforming growth factor beta (TGFß) signaling mediate superior tumor regression in an animal model of adoptive cell therapy.
Academic Article Immune rejection in a humanized model of murine prostate cancer.
Academic Article Molecular mechanism of MART-1+/A*0201+ human melanoma resistance to specific CTL-killing despite functional tumor-CTL interaction.
Academic Article Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
Academic Article Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.
Academic Article Immunosensitization with a Bcl-2 small molecule inhibitor.
Academic Article Neoantigens retention in patient derived xenograft models mediates autologous T cells activation in ovarian cancer.
Academic Article Tunable-combinatorial mechanisms of acquired resistance limit the efficacy of BRAF/MEK cotargeting but result in melanoma drug addiction.
Academic Article Inhibition of Alzheimer's amyloid-beta peptide-induced reduction of mitochondrial membrane potential and neurotoxicity by gelsolin.
Academic Article Adoptive cell transfer of T-cell receptor-engineered lymphocytes: lessons from recent modeling.
Academic Article Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition.
Academic Article Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
Academic Article Modular nucleic acid assembled p/MHC microarrays for multiplexed sorting of antigen-specific T cells.
Academic Article Frequent expression of new cancer/testis gene D40/AF15q14 in lung cancers of smokers.
Academic Article Making dendritic cells from the inside out: lentiviral vector-mediated gene delivery of granulocyte-macrophage colony-stimulating factor and interleukin 4 into CD14+ monocytes generates dendritic cells in vitro.
Academic Article Engineered microenvironment for the study of myofibroblast mechanobiology.
Academic Article CXCR6 by increasing retention of memory CD8+ T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer.
Academic Article Engineering tumor stromal mechanics for improved T cell therapy.
Academic Article Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses.
Academic Article Tcf-1 protects anti-tumor TCR-engineered CD8+ T-cells from GzmB mediated self-destruction.
Academic Article Correction to: Tcf-1 protects anti-tumor TCR-engineered CD8+ T-cells from GzmB mediated self-destruction.
Academic Article Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses.
Academic Article pH Sensitive Erythrocyte-Derived Membrane for Acute Systemic Retention and Increased Infectivity of Coated Oncolytic Vaccinia Virus.
Concept Erlotinib Hydrochloride
Concept Carbonic Anhydrase IX
Academic Article Implementation of a gene therapy education initiative by the ASGCT and Muhimbili University of Health and Allied Sciences.
Academic Article Host immunity contributes to the anti-melanoma activity of BRAF inhibitors.
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