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Search Results to Chuan He

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One or more keywords matched the following properties of He, Chuan

keywords DNA methylation
overview Chuan He is the John T. Wilson Distinguished Service Professor in the Department of Chemistry and Department of Biochemistry and Molecular Biology at the University of Chicago.He received his B.S. (1994) from the University of Science and Technology of China. He received his Ph. D. degree from Massachusetts Institute of Technology in chemistry in 2000. After being trained as a Damon-Runyon postdoctoral fellow at Harvard University from 2000-2002, he joined the University of Chicago as an Assistant Professor, and was promoted to Associate Professor in 2008, Professor in 2010 and John T. Wilson Distinguished Service Professor in 2014. He is also a member of the Cancer Research Center at the University of Chicago. His research spans a broad range of chemical biology, RNA biology, epigenetics, biochemistry, molecular biology, and genomics. His recent research concerns reversible RNA and DNA methylation in biological regulation. His research group discovered the first RNA demethylase and showed that reversible RNA methylation significantly affects gene expression regulation.

One or more keywords matched the following items that are connected to He, Chuan

Item TypeName
Concept DNA Methylation
Academic Article Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.
Academic Article Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
Academic Article Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing.
Academic Article Potential functional roles of DNA demethylation intermediates.
Academic Article Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA.
Academic Article Nonenzymatic labeling of 5-hydroxymethylcytosine in nanopore sequencing.
Academic Article Detection of mismatched 5-hydroxymethyluracil in DNA by selective chemical labeling.
Academic Article Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics.
Academic Article A non-heme iron-mediated chemical demethylation in DNA and RNA.
Academic Article Nucleic acid oxidation in DNA damage repair and epigenetics.
Academic Article Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system.
Academic Article Decoding the transcriptome and DNA methylome of human primordial germ cells.
Academic Article High-Resolution Mapping of N6-Methyladenosine in Transcriptome and Genome Using a Photo-Crosslinking-Assisted Strategy.
Academic Article DNA N(6)-methyladenine: a new epigenetic mark in eukaryotes?
Academic Article Detecting hepatocellular carcinoma in blood.
Academic Article Nucleic Acid Modifications in Regulation of Gene Expression.
Academic Article Characterization of eukaryotic DNA N(6)-methyladenine by a highly sensitive restriction enzyme-assisted sequencing.
Academic Article A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations.
Academic Article Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig.
Academic Article m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.
Academic Article 5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma.
Academic Article DNA 5-Methylcytosine-Specific Amplification and Sequencing.
Academic Article N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA.
Academic Article LEAD-m6 A-seq for Locus-Specific Detection of N6 -Methyladenosine and Quantification of Differential Methylation.
Academic Article A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation.

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  • DNA Methylation