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Concept
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Bacterial Outer Membrane Proteins
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Concept
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Bacterial Proteins
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Concept
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Fungal Proteins
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Concept
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DNA-Binding Proteins
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Concept
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Iron-Sulfur Proteins
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Concept
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Membrane Proteins
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Concept
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Nerve Tissue Proteins
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Concept
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Proto-Oncogene Proteins
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Concept
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Proteins
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Concept
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Repressor Proteins
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Concept
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Zebrafish Proteins
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Concept
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Proto-Oncogene Proteins c-myc
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Concept
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RNA-Binding Proteins
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Concept
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Nonheme Iron Proteins
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Concept
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Multidrug Resistance-Associated Proteins
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Concept
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Mitochondrial Proteins
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Concept
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Periplasmic Binding Proteins
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Concept
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S-Phase Kinase-Associated Proteins
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Concept
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Cell Cycle Proteins
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Concept
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Nucleocytoplasmic Transport Proteins
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Concept
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Arabidopsis Proteins
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Concept
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Saccharomyces cerevisiae Proteins
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Concept
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Recombinant Proteins
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Concept
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Ribosomal Proteins
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Concept
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Cullin Proteins
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Concept
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Homeodomain Proteins
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Concept
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Caenorhabditis elegans Proteins
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Concept
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Mutant Proteins
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Concept
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Escherichia coli Proteins
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Concept
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Fimbriae Proteins
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Concept
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Intracellular Signaling Peptides and Proteins
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Concept
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Suppressor of Cytokine Signaling Proteins
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Concept
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Pore Forming Cytotoxic Proteins
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Concept
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Chloroplast Proteins
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Concept
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Carrier Proteins
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Concept
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Luminescent Proteins
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Concept
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Neoplasm Proteins
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Concept
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Nuclear Proteins
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Concept
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Membrane Transport Proteins
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Concept
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Proto-Oncogene Proteins c-akt
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Academic Article
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Spectroscopic insights into lead(II) coordination by the selective lead(II)-binding protein PbrR691.
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Academic Article
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Intramolecular amide bonds stabilize pili on the surface of bacilli.
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Academic Article
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Isopeptide bonds of the major pilin protein BcpA influence pilus structure and bundle formation on the surface of Bacillus cereus.
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Academic Article
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A selective fluorescent probe for carbon monoxide imaging in living cells.
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Academic Article
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The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis.
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Academic Article
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Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus.
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Academic Article
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A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus.
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Academic Article
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Expression of multidrug resistance efflux pump gene norA is iron responsive in Staphylococcus aureus.
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Academic Article
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Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.
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Academic Article
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Binding of ReO4(-) with an engineered MoO4(2-)-binding protein: towards a new approach in radiopharmaceutical applications.
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Academic Article
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N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.
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Academic Article
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An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus.
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Academic Article
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Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
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Academic Article
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FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA.
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Academic Article
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HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis.
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Academic Article
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TET1 plays an essential oncogenic role in MLL-rearranged leukemia.
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Academic Article
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Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR.
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Academic Article
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N6-methyladenosine-dependent regulation of messenger RNA stability.
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Academic Article
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ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility.
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Academic Article
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The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism.
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Academic Article
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Preparation and characterization of the native iron(II)-containing DNA repair AlkB protein directly from Escherichia coli.
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Academic Article
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Molecular mechanisms of two-component system RhpRS regulating type III secretion system in Pseudomonas syringae.
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Academic Article
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Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases.
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Academic Article
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Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing.
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Academic Article
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An exceptionally selective lead(II)-regulatory protein from Ralstonia metallidurans: development of a fluorescent lead(II) probe.
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Academic Article
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Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
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Academic Article
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Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria.
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Academic Article
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Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO.
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Academic Article
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AirSR, a [2Fe-2S] cluster-containing two-component system, mediates global oxygen sensing and redox signaling in Staphylococcus aureus.
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Academic Article
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Staphylococcus aureus CymR is a new thiol-based oxidation-sensing regulator of stress resistance and oxidative response.
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Academic Article
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Engineering a uranyl-specific binding protein from NikR.
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Academic Article
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Aureusimines in Staphylococcus aureus are not involved in virulence.
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Academic Article
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Using the bias from flow to elucidate single DNA repair protein sliding and interactions with DNA.
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Academic Article
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Design of an emission ratiometric biosensor from MerR family proteins: a sensitive and selective sensor for Hg2+.
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Academic Article
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High-resolution N(6) -methyladenosine (m(6) A) map using photo-crosslinking-assisted m(6) A sequencing.
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Academic Article
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The Pseudomonas aeruginosa global regulator VqsR directly inhibits QscR to control quorum-sensing and virulence gene expression.
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Academic Article
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A highly sensitive and genetically encoded fluorescent reporter for ratiometric monitoring of quinones in living cells.
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Academic Article
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The tightly regulated copper window in yeast.
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Academic Article
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TET family proteins: oxidation activity, interacting molecules, and functions in diseases.
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Academic Article
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Quorum-sensing agr mediates bacterial oxidation response via an intramolecular disulfide redox switch in the response regulator AgrA.
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Academic Article
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Highly sensitive and selective gold(I) recognition by a metalloregulator in Ralstonia metallidurans.
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Academic Article
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How do DNA repair proteins locate potential base lesions? a chemical crosslinking method to investigate O6-alkylguanine-DNA alkyltransferases.
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Academic Article
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Crystal structures of SlyA protein, a master virulence regulator of Salmonella, in free and DNA-bound states.
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Academic Article
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Probing the structure and function of the Escherichia coli DNA alkylation repair AlkB protein through chemical cross-linking.
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Academic Article
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Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins.
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Academic Article
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A non-heme iron-mediated chemical demethylation in DNA and RNA.
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Academic Article
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Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins.
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Academic Article
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Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance.
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Academic Article
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A general strategy to convert the MerR family proteins into highly sensitive and selective fluorescent biosensors for metal ions.
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Academic Article
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Selective recognition of metal ions by metalloregulatory proteins.
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Academic Article
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Direct reversal of DNA alkylation damage.
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Academic Article
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A TET homologue protein from Coprinopsis cinerea (CcTET) that biochemically converts 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxylcytosine.
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Academic Article
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Reversible RNA adenosine methylation in biological regulation.
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Academic Article
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Crystal structure of the RNA demethylase ALKBH5 from zebrafish.
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Academic Article
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Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection.
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Academic Article
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Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2.
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Academic Article
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In the Staphylococcus aureus two-component system sae, the response regulator SaeR binds to a direct repeat sequence and DNA binding requires phosphorylation by the sensor kinase SaeS.
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Academic Article
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Interaction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies.
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Academic Article
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Reading RNA methylation codes through methyl-specific binding proteins.
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Academic Article
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Synthesis of a FTO inhibitor with anticonvulsant activity.
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Academic Article
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Targeting MgrA-mediated virulence regulation in Staphylococcus aureus.
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Academic Article
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Dynamic copper(I) imaging in mammalian cells with a genetically encoded fluorescent copper(I) sensor.
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Academic Article
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Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine.
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Academic Article
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Modeling non-heme iron proteins.
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Academic Article
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A protein engineered to bind uranyl selectively and with femtomolar affinity.
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Academic Article
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Engineering bacterial two-component system PmrA/PmrB to sense lanthanide ions.
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Academic Article
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N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency.
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Academic Article
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Preparation of Human Nuclear RNA m6A Methyltransferases and Demethylases and Biochemical Characterization of Their Catalytic Activity.
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Academic Article
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Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation.
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Academic Article
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Base-resolution detection of N4-methylcytosine in genomic DNA using 4mC-Tet-assisted-bisulfite- sequencing.
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Academic Article
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Identification of MLL-fusion/MYC?miR-26?TET1 signaling circuit in MLL-rearranged leukemia.
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Academic Article
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Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus.
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Academic Article
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Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing.
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Academic Article
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A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations.
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Academic Article
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FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase.
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Academic Article
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Developing drugs targeting transition metal homeostasis.
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Academic Article
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YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.
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Academic Article
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Chromate Binding and Removal by the Molybdate-Binding Protein ModA.
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Academic Article
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m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition.
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Academic Article
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m6A facilitates hippocampus-dependent learning and memory through YTHDF1.
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Academic Article
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FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function.
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Academic Article
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RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia.
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Academic Article
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m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.
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Academic Article
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YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs.
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Academic Article
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Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation.
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Academic Article
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Kinetic gating mechanism of DNA damage recognition by Rad4/XPC.
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Grant
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Mechanisms of Pancreatic Cancer Inhibition by SPARC
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Grant
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Mechanism of SPARC peptide FSEC inhibition of angiogenesis in neuroblastoma
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Academic Article
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Inhibition of Copper Transport Induces Apoptosis in Triple-Negative Breast Cancer Cells and Suppresses Tumor Angiogenesis.
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Academic Article
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Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis.
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Academic Article
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METTL14 is essential for ß-cell survival and insulin secretion.
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Academic Article
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N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA.
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Academic Article
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YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators.
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Academic Article
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Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation.
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Academic Article
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N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation.
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Academic Article
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N6 -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness.
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Academic Article
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ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing.
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Academic Article
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METTL14 facilitates global genome repair and suppresses skin tumorigenesis.
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Academic Article
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N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis.
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Academic Article
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The mechanism underlying redundant functions of the YTHDF proteins.
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Concept
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RNA Recognition Motif Proteins
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Concept
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Pancreatitis-Associated Proteins
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Concept
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Poly-ADP-Ribose Binding Proteins
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Grant
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Discovering the epigenetics of RNA modifications
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Grant
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RNA methylation and regulatory T cells
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Grant
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Recognition and mechanism of N6-methyl adenosine modifications
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Grant
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Global Cysteine Modifications in Human Pathogens
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Grant
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Direct Oxidative Nucleic Acids Demethylation
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Grant
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Base-resolution sequencing of m6A in RNA
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Grant
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Direct Oxidative Nucleic Acids Demethylation
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Academic Article
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YTHDF2 inhibition potentiates radiotherapy antitumor efficacy.
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Academic Article
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6mA-METL-9 axis regulates innate immunity in C. elegans.
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Academic Article
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RBFOX2 recognizes N6-methyladenosine to suppress transcription and block myeloid leukaemia differentiation.
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Academic Article
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FMRP phosphorylation modulates neuronal translation through YTHDF1.
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Academic Article
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Light-induced LLPS of the CRY2/SPA1/FIO1 complex regulating mRNA methylation and chlorophyll homeostasis in Arabidopsis.
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Academic Article
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Profiling of RNA-binding protein binding sites by in situ reverse transcription-based sequencing.
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Academic Article
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Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells.
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