| Item Type | Name |
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Concept
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American Heart Association
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Concept
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Genetic Association Studies
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Concept
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Genome-Wide Association Study
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Academic Article
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Hypertriglyceridemia and the apolipoprotein CIII gene locus: lack of association with the variant insulin response element in Italian school children.
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Academic Article
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Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom.
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Academic Article
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Association of the calpain-10 gene with type 2 diabetes mellitus in a Mexican population.
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Academic Article
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Findings in an independent sample support an association between bipolar affective disorder and the G72/G30 locus on chromosome 13q33.
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Academic Article
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Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder.
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Academic Article
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Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses.
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Academic Article
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Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects.
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Academic Article
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SNPs meet CNVs in genome-wide association studies: HGV2007 meeting report.
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Academic Article
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Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1.
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Academic Article
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Population-specific GSTM1 copy number variation.
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Academic Article
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Finding the missing heritability of complex diseases.
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Academic Article
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The neutrophil alloantigen HNA-3a (5b) is located on choline transporter-like protein 2 and appears to be encoded by an R>Q154 amino acid substitution.
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Academic Article
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The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population.
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Academic Article
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SCAN: SNP and copy number annotation.
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Academic Article
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Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS.
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Academic Article
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Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci.
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Academic Article
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Disease associations. Chance, artifact, or susceptibility genes?
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Academic Article
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Spoiling the whole bunch: quality control aimed at preserving the integrity of high-throughput genotyping.
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Academic Article
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Are genome-wide association studies all that we need to dissect the genetic component of complex human diseases?
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Academic Article
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Genetic variations in GRIA1 on chromosome 5q33 related to asparaginase hypersensitivity.
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Academic Article
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The missing association: sequencing-based discovery of novel SNPs in VKORC1 and CYP2C9 that affect warfarin dose in African Americans.
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Academic Article
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Genetic Analysis in Translational Medicine: The 2010 GOLDEN HELIX Symposium.
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Academic Article
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Population differences in microRNA expression and biological implications.
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Academic Article
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Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients.
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Academic Article
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Lack of association between common single nucleotide polymorphisms in the TERT-CLPTM1L locus and breast cancer in women of African ancestry.
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Academic Article
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Genome-wide meta-analysis for severe diabetic retinopathy.
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Academic Article
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Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry.
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Academic Article
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Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue.
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Academic Article
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Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects.
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Academic Article
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Replication analysis for severe diabetic retinopathy.
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Academic Article
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On sharing quantitative trait GWAS results in an era of multiple-omics data and the limits of genomic privacy.
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Academic Article
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Maternal transmission of a rare GABRB3 signal peptide variant is associated with autism.
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Academic Article
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PACdb: a database for cell-based pharmacogenomics.
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Academic Article
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Comprehensive evaluation of the contribution of X chromosome genes to platinum sensitivity.
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Academic Article
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Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County, Texas.
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Academic Article
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Power and sample size calculations for SNP association studies with censored time-to-event outcomes.
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Academic Article
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Copy number polymorphisms and anticancer pharmacogenomics.
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Academic Article
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Next generation analytic tools for large scale genetic epidemiology studies of complex diseases.
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Academic Article
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Association of attention-deficit disorder and the dopamine transporter gene.
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Academic Article
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Genome-wide association study to identify novel loci associated with therapy-related myeloid leukemia susceptibility.
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Academic Article
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A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose.
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Academic Article
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Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study: common genetic variants in GCK and TCF7L2 are associated with fasting and postchallenge glucose levels in pregnancy and with the new consensus definition of gestational diabetes mellitus from the International Association of Diabetes and Pregnancy Study Groups.
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Academic Article
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Identification of Diabetic Retinopathy Genes through a Genome-Wide Association Study among Mexican-Americans from Starr County, Texas.
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Academic Article
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A study of CNVs as trait-associated polymorphisms and as expression quantitative trait loci.
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Academic Article
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The use of genomic information to optimize cancer chemotherapy.
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Academic Article
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Identification of novel germline polymorphisms governing capecitabine sensitivity.
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Academic Article
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The importance of genealogy in determining genetic associations with complex traits.
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Academic Article
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Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies.
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Academic Article
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Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers.
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Academic Article
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Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
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Academic Article
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Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans.
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Academic Article
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Genetic architecture of microRNA expression: implications for the transcriptome and complex traits.
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Academic Article
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Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia.
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Academic Article
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[The association of non-insulin-dependent diabetes mellitus with the genes responsible for carbohydrate and lipid metabolism in the Chinese].
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Academic Article
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Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.
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Academic Article
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Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
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Academic Article
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Fine mapping of breast cancer genome-wide association studies loci in women of African ancestry identifies novel susceptibility markers.
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Academic Article
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Genome-wide association study of Tourette's syndrome.
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Academic Article
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Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations.
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Academic Article
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A genome-wide association study of breast cancer in women of African ancestry.
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Academic Article
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Cancer pharmacogenomics: strategies and challenges.
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Academic Article
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Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases.
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Academic Article
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An exponential combination procedure for set-based association tests in sequencing studies.
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Academic Article
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Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients.
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Academic Article
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A genome-wide integrative study of microRNAs in human liver.
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Academic Article
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Genome-wide association study of obsessive-compulsive disorder.
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Academic Article
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SCAN: a systems biology approach to pharmacogenomic discovery.
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Academic Article
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Genome-wide interrogation of longitudinal FEV1 in children with asthma.
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Academic Article
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Integrative analyses of genetic variation, epigenetic regulation, and the transcriptome to elucidate the biology of platinum sensitivity.
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Academic Article
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A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk.
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Academic Article
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A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.
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Academic Article
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Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.
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Academic Article
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Genetic association signal near NTN4 in Tourette syndrome.
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Academic Article
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Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.
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Academic Article
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Genome-wide association studies in pharmacogenomics: successes and lessons.
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Academic Article
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A haplotype-based framework for group-wise transmission/disequilibrium tests for rare variant association analysis.
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Academic Article
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The chromosome 3q25 genomic region is associated with measures of adiposity in newborns in a multi-ethnic genome-wide association study.
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Academic Article
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Identification of a variant in KDR associated with serum VEGFR2 and pharmacodynamics of Pazopanib.
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Academic Article
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Structural architecture of SNP effects on complex traits.
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Academic Article
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Cross-tissue and tissue-specific eQTLs: partitioning the heritability of a complex trait.
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Academic Article
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Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.
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Academic Article
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Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.
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Academic Article
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Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.
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Academic Article
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Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium.
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Academic Article
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Genome-wide identification of microRNA expression quantitative trait loci.
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Academic Article
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Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.
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Academic Article
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Quantitative allelic test--a fast test for very large association studies.
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Academic Article
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Identifying plausible genetic models based on association and linkage results: application to type 2 diabetes.
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Academic Article
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Chemotherapy-induced peripheral neurotoxicity and ototoxicity: new paradigms for translational genomics.
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Academic Article
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Integrating cell-based and clinical genome-wide studies to identify genetic variants contributing to treatment failure in neuroblastoma patients.
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Academic Article
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Genome wide association studies for diabetes: perspective on results and challenges.
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Academic Article
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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
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Academic Article
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A genome-wide sib-pair scan for quantitative language traits reveals linkage to chromosomes 10 and 13.
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Academic Article
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A gene-based association method for mapping traits using reference transcriptome data.
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Academic Article
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Ethnic variation of TET2 SNP rs2454206 and association with clinical outcome in childhood AML: a report from the Children's Oncology Group.
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Academic Article
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Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.
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Academic Article
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A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology.
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Academic Article
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Pharmacogenomic variants have larger effect sizes than genetic variants associated with other dichotomous complex traits.
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Academic Article
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The genetic architecture of type 2 diabetes.
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Academic Article
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Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms.
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Academic Article
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STAMS: STRING-assisted module search for genome wide association studies and application to autism.
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Academic Article
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Variants in WFS1 and Other Mendelian Deafness Genes Are Associated with Cisplatin-Associated Ototoxicity.
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Academic Article
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Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer.
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Academic Article
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Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal.
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Academic Article
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Clinical and Genome-Wide Analysis of Cisplatin-Induced Peripheral Neuropathy in Survivors of Adult-Onset Cancer.
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Academic Article
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Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome.
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Academic Article
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Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record.
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Academic Article
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Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation.
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Academic Article
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Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.
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Academic Article
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Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees.
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Academic Article
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Integrative genetic analysis suggests that skin color modifies the genetic architecture of melanoma.
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Academic Article
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Phenotype risk scores identify patients with unrecognized Mendelian disease patterns.
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Academic Article
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Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
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Academic Article
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An integrative functional genomics framework for effective identification of novel regulatory variants in genome-phenome studies.
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Academic Article
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LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins.
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Academic Article
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Up For A Challenge (U4C): Stimulating innovation in breast cancer genetic epidemiology.
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Academic Article
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Reaching for the next branch on the biobank tree of knowledge.
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Academic Article
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Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
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Academic Article
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Evidence of selection on splicing-associated loci in human populations and relevance to disease loci mapping.
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Academic Article
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Sex-specific genetic predictors of Alzheimer's disease biomarkers.
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Academic Article
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Critical Evaluation of Data Requires Rigorous but Broadly Based Statistical Inference.
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Academic Article
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Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies.
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Academic Article
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Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.
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Academic Article
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Clinical and Genome-wide Analysis of Cisplatin-induced Tinnitus Implicates Novel Ototoxic Mechanisms.
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Academic Article
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A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data.
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Academic Article
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Multi-tissue transcriptome analyses identify genetic mechanisms underlying neuropsychiatric traits.
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Academic Article
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Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
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Academic Article
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Sex differences in the genetic predictors of Alzheimer's pathology.
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Academic Article
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Genetic risk for major depressive disorder and loneliness in sex-specific associations with coronary artery disease.
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Academic Article
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APOE e4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease.
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Academic Article
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Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies.
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Academic Article
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Combining clinical and candidate gene data into a risk score for azathioprine-associated leukopenia in routine clinical practice.
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Academic Article
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Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis: A Phenome-Wide Association Study and Inverse Variance-Weighted Meta-Analysis.
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Academic Article
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Genetic variants and functional pathways associated with resilience to Alzheimer's disease.
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Academic Article
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A Transcriptome-Wide Association Study Identifies Candidate Susceptibility Genes for Pancreatic Cancer Risk.
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Academic Article
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PheMap: a multi-resource knowledge base for high-throughput phenotyping within electronic health records.
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Academic Article
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A unified framework for joint-tissue transcriptome-wide association and Mendelian randomization analysis.
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Academic Article
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Host genetic effects in pneumonia.
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Academic Article
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Synaptic processes and immune-related pathways implicated in Tourette syndrome.
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Academic Article
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Alcohol and cigarette smoking consumption as genetic proxies for alcohol misuse and nicotine dependence.
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Academic Article
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Fate or coincidence: do COPD and major depression share genetic risk factors?
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Academic Article
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Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis.
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Academic Article
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Recommendations for Statistical Reporting in Cardiovascular Medicine: A Special Report From the American Heart Association.
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Academic Article
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High-throughput framework for genetic analyses of adverse drug reactions using electronic health records.
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Academic Article
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Association Between a Common, Benign Genotype and Unnecessary Bone Marrow Biopsies Among African American Patients.
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Academic Article
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Analyses of biomarker traits in diverse UK biobank participants identify associations missed by European-centric analysis strategies.
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Academic Article
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A transcriptome-wide association study identifies novel blood-based gene biomarker candidates for Alzheimer's disease risk.
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Academic Article
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A transcriptome-wide association study of Alzheimer's disease using prediction models of relevant tissues identifies novel candidate susceptibility genes.
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Academic Article
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A transcriptome-wide association study identifies novel candidate susceptibility genes for prostate cancer risk.
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Academic Article
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Discovery and implications of polygenicity of common diseases.
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Academic Article
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Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.
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Academic Article
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Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults.
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Academic Article
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Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries.
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Academic Article
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Pharmacogenomics of cisplatin-induced neurotoxicities: Hearing loss, tinnitus, and peripheral sensory neuropathy.
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Academic Article
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Two polymorphic gene loci associated with treprostinil dose in pulmonary arterial hypertension.
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Academic Article
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Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.
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Academic Article
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Improving the computation efficiency of polygenic risk score modeling: faster in Julia.
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Academic Article
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Association of Genetically Predicted Fibroblast Growth Factor-23 with Heart Failure: A Mendelian Randomization Study.
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Academic Article
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Comprehensive association analysis of speech recognition thresholds after cisplatin-based chemotherapy in survivors of adult-onset cancer.
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Academic Article
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Best practices for multi-ancestry, meta-analytic transcriptome-wide association studies: Lessons from the Global Biobank Meta-analysis Initiative.
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Academic Article
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Discerning asthma endotypes through comorbidity mapping.
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Academic Article
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Interactive network-based clustering and investigation of multimorbidity association matrices with associationSubgraphs.
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Academic Article
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Genome-wide association analyses of common infections in a large practice-based biobank.
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Academic Article
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Obesity and Overweight: Probing Causes, Consequences, and Novel Therapeutic Approaches Through the American Heart Association's Strategically Focused Research Network.
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Academic Article
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Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes.
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Academic Article
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Cross-talks between gut microbiota and tobacco smoking: a two-sample Mendelian randomization study.
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Academic Article
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Genetic Variants Associated With Hidradenitis Suppurativa.
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Academic Article
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Genetic examination of hematological parameters in SARS-CoV-2 infection and COVID-19.
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Academic Article
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Association between APOL1 risk variants and the occurrence of sepsis in Black patients hospitalized with infections: a retrospective cohort study.
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Academic Article
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Association between APOL1 risk variants and the occurrence of sepsis in Black patients hospitalized with infections: a retrospective cohort study.
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Academic Article
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Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing.
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Academic Article
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The high-dimensional space of human diseases built from diagnosis records and mapped to genetic loci.
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Academic Article
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Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-differential effects via GAUDI.
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