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Godley, Lucy
One or more keywords matched the following items that are connected to Godley, Lucy
Item TypeName
Concept 5-Methylcytosine
Academic Article Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
Academic Article Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Academic Article Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors.
Academic Article Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia.
Academic Article 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
Academic Article Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis.
Academic Article 2-Hydroxyglutarate in IDH mutant acute myeloid leukemia: predicting patient responses, minimal residual disease and correlations with methylcytosine and hydroxymethylcytosine levels.
Academic Article Perturbations of 5-hydroxymethylcytosine patterning in hematologic malignancies.
Academic Article Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
Academic Article TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.
Academic Article Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.
Academic Article New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine.
Academic Article DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Academic Article Large conserved domains of low DNA methylation maintained by Dnmt3a.
Academic Article 5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy.
Academic Article TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer.
Academic Article Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways.
Academic Article 5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma.
Academic Article MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia.
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  • 5 Methylcytosine