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Histone Deacetylase Inhibitors
Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines.
The use of hypomethylating agents in the treatment of hematologic malignancies.
Gene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet?
The histone code and treatments for acute myeloid leukemia.
Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation.
Histone-lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, cell invasion, and DNA methylation of human neuroblastoma cells.
Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
A phase I and pharmacodynamic study of the histone deacetylase inhibitor belinostat plus azacitidine in advanced myeloid neoplasia.
Large conserved domains of low DNA methylation maintained by Dnmt3a.
Linking the genetic architecture of cytosine modifications with human complex traits.
Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma.
Mutant RUNX1 and histone tales.
Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways.
(R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers.
The Role of DNMT3B in the DNA Methylation of Cancer Cells