| Item Type | Name |
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Concept
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Methylation
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Concept
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DNA Methylation
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Academic Article
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Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins.
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Academic Article
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Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines.
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Academic Article
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Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage.
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Academic Article
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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
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Academic Article
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The use of hypomethylating agents in the treatment of hematologic malignancies.
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Academic Article
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DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation.
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Academic Article
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Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors.
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Academic Article
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Characterization of NOL7 gene point mutations, promoter methylation, and protein expression in cervical cancer.
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Academic Article
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Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma.
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Academic Article
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Molecular biology. Preference by exclusion.
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Academic Article
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Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia.
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Academic Article
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An integrated genomic approach to the assessment and treatment of acute myeloid leukemia.
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Academic Article
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Dnmt3a is essential for hematopoietic stem cell differentiation.
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Academic Article
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Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis.
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Academic Article
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5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
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Academic Article
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DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.
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Academic Article
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Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis.
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Academic Article
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High resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis.
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Academic Article
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Genome-wide variation of cytosine modifications between European and African populations and the implications for complex traits.
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Academic Article
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Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis.
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Academic Article
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Histone-lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, cell invasion, and DNA methylation of human neuroblastoma cells.
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Academic Article
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Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
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Academic Article
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TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.
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Academic Article
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Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma.
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Academic Article
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New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine.
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Academic Article
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Large conserved domains of low DNA methylation maintained by Dnmt3a.
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Academic Article
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DNMT3B7 expression promotes tumor progression to a more aggressive phenotype in breast cancer cells.
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Academic Article
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The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide.
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Academic Article
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Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes.
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Academic Article
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The mechanistic role of DNA methylation in myeloid leukemogenesis.
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Academic Article
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TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.
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Academic Article
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5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy.
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Academic Article
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Characterization of CpG sites that escape methylation on the inactive human X-chromosome.
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Academic Article
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DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.
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Academic Article
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Increased DNA methylation of Dnmt3b targets impairs leukemogenesis.
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Academic Article
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Rigosertib versus best supportive care for patients with high-risk myelodysplastic syndromes after failure of hypomethylating drugs (ONTIME): a randomised, controlled, phase 3 trial.
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Academic Article
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MBD4: guardian of the epigenetic galaxy.
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Academic Article
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Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4+ and CD8+ T-lymphocytes.
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Academic Article
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5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma.
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Academic Article
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Regulation of telomeric function by DNA methylation differs between humans and mice.
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Academic Article
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RBL2 bi-allelic truncating variants cause severe motor and cognitive impairment without evidence for abnormalities in DNA methylation or telomeric function.
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Academic Article
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MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia.
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Academic Article
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(R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers.
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Grant
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The Role of DNMT3B in the DNA Methylation of Cancer Cells
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Grant
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A chemical crosslinking strategy to determine DNA methylating protein complexes
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Grant
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Epigenetic and Genetic Dissection of Drug Response
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