Item Type | Name |
Concept
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DNA Damage
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Concept
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DNA-Binding Proteins
|
Concept
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DNA Mutational Analysis
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Concept
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DNA, Neoplasm
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Concept
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DNA
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Concept
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DNA Topoisomerases, Type II
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Concept
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DNA-Directed DNA Polymerase
|
Concept
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DNA Viruses
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Concept
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DNA, Viral
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Concept
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DNA-Directed RNA Polymerases
|
Concept
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Sequence Analysis, DNA
|
Concept
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DNA, Complementary
|
Concept
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DNA-Activated Protein Kinase
|
Concept
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DNA Fragmentation
|
Concept
|
DNA, Single-Stranded
|
Concept
|
DNA Primers
|
Academic Article
|
Redefining virology.
|
Academic Article
|
Bcl-2 blocks a caspase-dependent pathway of apoptosis activated by herpes simplex virus 1 infection in HEp-2 cells.
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Academic Article
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Molecular targeting of gene therapy and radiotherapy.
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Academic Article
|
An early regulatory function required in a cell type-dependent manner is expressed by the genomic but not the cDNA copy of the herpes simplex virus 1 gene encoding infected cell protein 0.
|
Academic Article
|
E2F proteins are posttranslationally modified concomitantly with a reduction in nuclear binding activity in cells infected with herpes simplex virus 1.
|
Academic Article
|
RNAs extracted from herpes simplex virus 1 virions: apparent selectivity of viral but not cellular RNAs packaged in virions.
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Academic Article
|
The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins.
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Academic Article
|
cdc2 cyclin-dependent kinase binds and phosphorylates herpes simplex virus 1 U(L)42 DNA synthesis processivity factor.
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Academic Article
|
Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts.
|
Academic Article
|
Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes.
|
Academic Article
|
Engineered herpes simplex virus 1 is dependent on IL13Ralpha 2 receptor for cell entry and independent of glycoprotein D receptor interaction.
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Academic Article
|
Requirements for the nuclear-cytoplasmic translocation of infected-cell protein 0 of herpes simplex virus 1.
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Academic Article
|
The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific.
|
Academic Article
|
STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.
|
Academic Article
|
Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites.
|
Academic Article
|
Receiver operating characteristic analysis: a general tool for DNA array data filtration and performance estimation.
|
Academic Article
|
Herpes simplex virus 1 ICP22 regulates the accumulation of a shorter mRNA and of a truncated US3 protein kinase that exhibits altered functions.
|
Academic Article
|
The first 30 minutes in the life of a virus: unREST in the nucleus.
|
Academic Article
|
Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses.
|
Academic Article
|
Herpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAs.
|
Academic Article
|
State and role of SRC family kinases in replication of herpes simplex virus 1.
|
Academic Article
|
Proteolytic cleavage of VP1-2 is required for release of herpes simplex virus 1 DNA into the nucleus.
|
Academic Article
|
Temperature-sensitive mutations in the putative herpes simplex virus type 1 terminase subunits pUL15 and pUL33 preclude viral DNA cleavage/packaging and interaction with pUL28 at the nonpermissive temperature.
|
Academic Article
|
Replication-competent herpes simplex virus 1 isolates selected from cells transfected with a bacterial artificial chromosome DNA lacking only the UL49 gene vary with respect to the defect in the UL41 gene encoding host shutoff RNase.
|
Academic Article
|
An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer.
|
Academic Article
|
Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus.
|
Academic Article
|
Components of the REST/CoREST/histone deacetylase repressor complex are disrupted, modified, and translocated in HSV-1-infected cells.
|
Academic Article
|
Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling.
|
Academic Article
|
Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNase.
|
Academic Article
|
Interwoven roles of cyclin D3 and cdk4 recruited by ICP0 and ICP4 in the expression of herpes simplex virus genes.
|
Academic Article
|
Herpes simplex virus-infected cell protein 0 blocks the silencing of viral DNA by dissociating histone deacetylases from the CoREST-REST complex.
|
Academic Article
|
The histone acetyltransferase CLOCK is an essential component of the herpes simplex virus 1 transcriptome that includes TFIID, ICP4, ICP27, and ICP22.
|
Academic Article
|
Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth.
|
Academic Article
|
The two functions of herpes simplex virus 1 ICP0, inhibition of silencing by the CoREST/REST/HDAC complex and degradation of PML, are executed in tandem.
|
Academic Article
|
Circadian CLOCK histone acetyl transferase localizes at ND10 nuclear bodies and enables herpes simplex virus gene expression.
|
Academic Article
|
Overexpression of the ubiquitin-specific protease 7 resulting from transfection or mutations in the ICP0 binding site accelerates rather than depresses herpes simplex virus 1 gene expression.
|
Academic Article
|
During its nuclear phase the multifunctional regulatory protein ICP0 undergoes proteolytic cleavage characteristic of polyproteins.
|
Academic Article
|
The disappearance of cyclins A and B and the increase in activity of the G(2)/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the alpha22/U(S)1.5 and U(L)13 viral genes.
|
Academic Article
|
Identification of a novel expressed open reading frame situated between genes U(L)20 and U(L)21 of the herpes simplex virus 1 genome.
|
Academic Article
|
Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1.
|
Academic Article
|
Post-transcriptional processing of cellular RNAs in herpes simplex virus-infected cells.
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Academic Article
|
Nuclear retention of ICP0 in cells exposed to HDAC inhibitor or transfected with DNA before infection with herpes simplex virus 1.
|
Academic Article
|
Engagement of the lysine-specific demethylase/HDAC1/CoREST/REST complex by herpes simplex virus 1.
|
Academic Article
|
ICP0 enables and monitors the function of D cyclins in herpes simplex virus 1 infected cells.
|
Academic Article
|
Use of biotinylated plasmid DNA as a surrogate for HSV DNA to identify proteins that repress or activate viral gene expression.
|
Academic Article
|
Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein.
|
Academic Article
|
Interaction of herpes simplex virus ICP0 with ND10 bodies: a sequential process of adhesion, fusion, and retention.
|
Academic Article
|
Role of activating transcription factor 3 in the synthesis of latency-associated transcript and maintenance of herpes simplex virus 1 in latent state in ganglia.
|
Grant
|
MOLECULAR BIOLOGY OF HERPES SIMPLEX VIRUSES
|
Grant
|
FUNCTIONS FOR HERPES SIMPLEX VIRUS ICP22 AND US1.5
|
Grant
|
The functions of the US3 protein kinase of herpes simplex virus
|
Grant
|
Dissection of the Functions of Herpes Simplex Virus ICPO
|
Grant
|
MECHANISMS OF VIRAL INFECTION IN RELATION TO CANCER
|
Grant
|
CONFERENCE ON CONTROL OF VIRAL LATENCY AND PERSISTENCE
|
Grant
|
MECHANISMS OF VIRAL INFECTION IN RELATION TO CANCER
|
Grant
|
HERPES SIMPLEX VIRUS MULTIPLICATION
|